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Best Female Scientists

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Molecular Biology

D-Index
108
Citations
34356
World Ranking
402
National Ranking
230

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2017 - Distinguished Scientist Award, American Heart Association
  • 2016 - Fellow, National Academy of Inventors
  • 2014 - Fellow of the American Academy of Arts and Sciences
  • 2005 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Leslie A. Leinwand is affiliated with the University of Colorado Boulder in the United States. Their research spans multiple fields within medicine and biochemistry, genetics, and molecular biology, with a strong focus on cardiology and cardiovascular medicine. Their primary subfields of study include cardiology and cardiovascular medicine, molecular biology, infectious diseases, biomedical engineering, and physiology.

The main topics covered in Leinwand's work involve:

  • Cardiomyopathy and myosin studies
  • Cardiovascular effects of exercise
  • Muscle physiology and disorders
  • SARS-CoV-2 detection and testing
  • Cardiac fibrosis and remodeling
  • RNA research and splicing
  • Physiological and biochemical adaptations

Leslie A. Leinwand's recent notable publications include:

  • "Just 2% of SARS-CoV-2−positive individuals carry 90% of the virus circulating in communities" (2021) published in Proceedings of the National Academy of Sciences
  • "Nuclear mechanosensing drives chromatin remodelling in persistently activated fibroblasts" (2021) published in Nature Biomedical Engineering
  • "Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential" (2023) published in Nature Reviews Cardiology
  • "Targeting the sarcomere in inherited cardiomyopathies" (2022) published in Nature Reviews Cardiology
  • "Associations Between Female Sex, Sarcomere Variants, and Clinical Outcomes in Hypertrophic Cardiomyopathy" (2020) published in Circulation Genomic and Precision Medicine

Key frequent co-authors working with Leinwand include:

  • Thomas G. Martin
  • Christopher D. Ozeroff
  • Claudia Crocini
  • Roy Parker
  • Dakota R. Hunt

Leinwand's research is regularly published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • Proceedings of the National Academy of Sciences
  • Circulation Research
  • Nature Reviews Cardiology

Their contributions to science have been recognized through awards including:

  • Distinguished Scientist Award, American Heart Association (2017)
  • Fellow, National Academy of Inventors (2016)
  • Fellow of the American Academy of Arts and Sciences (2014)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2005)

Best Publications

  • Right Ventricular Function and Failure Report of a National Heart, Lung, and Blood Institute Working Group on Cellular and Molecular Mechanisms of Right Heart Failure

    Norbert F. Voelkel;Robert A. Quaife;Leslie A. Leinwand;Robyn J. Barst

  • Gene for von Recklinghausen neurofibromatosis is in the pericentromeric region of chromosome 17

    D. Barker;E. Wright;K. Nguyen;L. Cannon

  • Cells: a laboratory manual

    David L. Spector;Robert D. Goldman;Leslie A. Leinwand

  • A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy.

    Jorge L. Ruas;James P. White;Rajesh Rajesh R Rao;Sandra Kleiner

  • Using mini-prep plasmid DNA for sequencing double stranded templates with Sequenase.

    R Kraft;J Tardiff;K S Krauter;L A Leinwand

  • Ubiquitous, interspersed repeated sequences in mammalian genomes

    Warren R. Jelinek;Thomas P. Toomey;Leslie Leinwand;Craig H. Duncan

  • A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice

    Eric M. Green;Hiroko Wakimoto;Robert L. Anderson;Marc J. Evanchik

  • Evidence that opioids may have toll-like receptor 4 and MD-2 effects

    Mark R. Hutchinson;Yingning Zhang;Mitesh Shridhar;John H. Evans

  • Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle

    V. Smerdu;I. Karsch-Mizrachi;M. Campione;L. Leinwand

  • Myosin heavy chain gene expression in human heart failure.

    Koichi Nakao;Wayne Minobe;Robert Roden;Michael R. Bristow

  • Hepatocyte proliferation in vitro: its dependence on the use of serum-free hormonally defined medium and substrata of extracellular matrix.

    Rafael Enat;Douglas M. Jefferson;Nelson Ruiz-Opazo;Zenaida Gatmaitan

  • A Role for Proinflammatory Cytokines and Fractalkine in Analgesia, Tolerance, and Subsequent Pain Facilitation Induced by Chronic Intrathecal Morphine

    Ian N. Johnston;Erin D. Milligan;Julie Wieseler-Frank;Matthew G. Frank

  • THE MAMMALIAN MYOSIN HEAVY CHAIN GENE FAMILY

    Allison Weiss;Leslie A. Leinwand

  • Developmental myosins: expression patterns and functional significance

    Stefano Schiaffino;Alberto C. Rossi;Vika Smerdu;Leslie A. Leinwand

  • Cardiac and skeletal muscle adaptations to voluntary wheel running in the mouse

    David L. Allen;Brooke C. Harrison;Alexander Maass;Matthew L. Bell

  • Cellular mechanisms of cardiomyopathy

    Pamela A. Harvey;Leslie A. Leinwand

  • Adenovirus Type 5 and 7 Capsid Chimera: Fiber Replacement Alters Receptor Tropism without Affecting Primary Immune Neutralization Epitopes

    J Gall;A Kass-Eisler;L Leinwand;E Falck-Pedersen

  • The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity

    Jayakrishnan Nandakumar;Jayakrishnan Nandakumar;Caitlin F. Bell;Caitlin F. Bell;Caitlin F. Bell;Ina Weidenfeld;Arthur J. Zaug;Arthur J. Zaug

  • Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats.

    Annemarie Ledeboer;Brian M. Jekich;Evan M. Sloane;John H. Mahoney

  • Corrigenda for vol. Cardiac and skeletal muscle adaptations to voluntary wheel running in the mouse (vol 90, pg 1900, 2001)

    DL Allan;BC Harrison;A Maass;ML Bell

Frequent Co-Authors

Kristi S. Anseth
Kristi S. Anseth University of Colorado Boulder
Linda R. Watkins
Linda R. Watkins University of Colorado Boulder
Erin D. Milligan
Erin D. Milligan University of New Mexico
James A. Spudich
James A. Spudich Stanford University
Michael A. Geeves
Michael A. Geeves University of Kent
Michael R. Bristow
Michael R. Bristow University of Colorado Anschutz Medical Campus
Steven F. Maier
Steven F. Maier University of Colorado Boulder
Elizabeth M. McNally
Elizabeth M. McNally Northwestern University
Frank H. Ruddle
Frank H. Ruddle Yale University
Stephen M. Factor
Stephen M. Factor Albert Einstein College of Medicine

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