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Christine E. Seidman

Christine E. Seidman

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Best Scientists
2025
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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
168
Citations
109404
World Ranking
70
National Ranking
42

Best Scientists

D-Index
168
Citations
109404
World Ranking
945
National Ranking
560

Medicine

D-Index
169
Citations
114561
World Ranking
542
National Ranking
319

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2025 - Research.com Best Scientists Award
  • 2018 - Libin/AHFMR Prize in Cardiovascular Research
  • 2005 - Member of the National Academy of Sciences
  • 2003 - Distinguished Scientist Award, American Heart Association
  • 1999 - Fellow of the American Academy of Arts and Sciences
  • 1999 - Member of the National Academy of Medicine (NAM)
  • 1991 - Robert J. and Claire Pasarow Foundation Medical Research Award
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Christine E. Seidman is affiliated with Harvard University in the United States and has contributed extensively to research in medicine, with particular emphasis on biochemistry, genetics, and molecular biology. Their work spans several subfields, including molecular biology, cardiology and cardiovascular medicine, epidemiology, genetics, and surgery.

Their research encompasses a range of main topics focused on cardiomyopathy and myosin studies, congenital heart defects, RNA modifications and cancer, viral infections and immunology, as well as cardiovascular effects of exercise and cardiovascular function and risk factors.

Key recent publications include:

  • Cells of the adult human heart, 2020, Nature
  • Loss of epigenetic information as a cause of mammalian aging, 2023, Cell
  • Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy, 2020, Circulation
  • Complement genes contribute sex-biased vulnerability in diverse disorders, 2020, Nature
  • Genomic frontiers in congenital heart disease, 2021, Nature Reviews Cardiology

The scientist has collaborated frequently with several co-authors, including Jonathan G. Seidman, Joshua Gorham, Sarah U. Morton, Bruce D. Gelb, and Steven R. DePalma.

Their work has appeared predominantly in venues such as Circulation, bioRxiv (Cold Spring Harbor Laboratory), Circulation Research, Circulation Genomic and Precision Medicine, and the Proceedings of the National Academy of Sciences.

Awards recognizing their contributions include the Libin/AHFMR Prize in Cardiovascular Research (2018), membership in the National Academy of Sciences (2005), Distinguished Scientist Award from the American Heart Association (2003), membership in the National Academy of Medicine (1999), fellowship in the American Academy of Arts and Sciences (1999), the Robert J. and Claire Pasarow Foundation Medical Research Award (1991), and membership in the Association of American Physicians.

Best Publications

  • Contemporary Definitions and Classification of the Cardiomyopathies An American Heart Association Scientific Statement From the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention

    Barry J. Maron;Jeffrey A. Towbin;Gaetano Thiene;Charles Antzelevitch

  • 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.

    Bernard J. Gersh;Barry J. Maron;Robert O. Bonow;Joseph A. Dearani;Joseph A. Dearani

  • American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European Society of Cardiology Committee for Practice Guidelines

    Barry J. Maron;William J. McKenna;Gordon K. Danielson;Lukas J. Kappenberger

  • Fulminant Myocarditis with Combination Immune Checkpoint Blockade

    Douglas B. Johnson;Justin M. Balko;Margaret L. Compton;Spyridon Chalkias

  • A molecular basis for familial hypertrophic cardiomyopathy: A β cardiac myosin heavy chain gene missense mutation

    Anja A.T. Geisterfer-Lowrance;Susan Kass;Gary Tanigawa;Hans-Peter Vosberg

  • 2011 ACCF/AHA Guideline for the Diagnosis and Treatment of Hypertrophic Cardiomyopathy: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in Collaboration With the American Association for Thoracic Surgery, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Failure Society of America, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons

    Bernard J. Gersh;Barry J. Maron;Robert O. Bonow;Joseph A. Dearani

  • Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome.

    Craig T. Basson;David R. Bachinsky;Robert C. Lin;Tatjana Levi

  • Congenital Heart Disease Caused by Mutations in the Transcription Factor NKX2-5

    Jean Jacques Schott;D. Woodrow Benson;Craig T. Basson;William Pease

  • Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease.

    Diane Fatkin;Calum MacRae;Takeshi Sasaki;Matthew R. Wolff

  • The Genetic Basis for Cardiomyopathy: from Mutation Identification to Mechanistic Paradigms

    J.G. Seidman;Christine Seidman

  • Truncations of Titin Causing Dilated Cardiomyopathy

    Daniel S. Herman;Lien Lam;Matthew R.G. Taylor;Libin Wang

  • Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere.

    Ludwig Thierfelder;Ludwig Thierfelder;Hugh Watkins;Hugh Watkins;Calum MacRae;Calum MacRae;Roger Lamas

  • The management of hypertrophic cardiomyopathy.

    Paolo Spirito;Christine E. Seidman;William J. McKenna;Barry J. Maron

  • Mutations in the genes for cardiac troponin T and alpha-tropomyosin in hypertrophic cardiomyopathy.

    Watkins H;McKenna Wj;Thierfelder L;Suk Hj

  • A Murine Model of Holt-Oram Syndrome Defines Roles of the T-Box Transcription Factor Tbx5 in Cardiogenesis and Disease

    Benoit G. Bruneau;Georges Nemer;Joachim P. Schmitt;Frédéric Charron

  • Cells of the adult human heart.

    Monika Litviňuková;Monika Litviňuková;Carlos Talavera-López;Carlos Talavera-López;Henrike Maatz;Daniel Reichart;Daniel Reichart

  • Mutations in the human Ca2+-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism

    Martin R. Pollak;Edward M. Brown;Yah-Huei Wu Chou;Steven C. Hebert

  • De novo mutations in histone-modifying genes in congenital heart disease

    Samir Zaidi;Murim Choi;Hiroko Wakimoto;Lijiang Ma

  • Mutations in the gene for cardiac myosin-binding protein C and late-onset familial hypertrophic cardiomyopathy.

    H Niimura;L L Bachinski;S Sangwatanaroj;H Watkins

  • A human MSX1 homeodomain missense mutation causes selective tooth agenesis

    Heleni Vastardis;Nadeem Karimbux;Symon W. Guthua;J.G. Seidman

Frequent Co-Authors

Jonathan G. Seidman
Jonathan G. Seidman Harvard University
Hugh Watkins
Hugh Watkins University of Oxford
Calum A. MacRae
Calum A. MacRae Brigham and Women's Hospital
Stuart A. Cook
Stuart A. Cook Duke NUS Graduate Medical School
Bruce D. Gelb
Bruce D. Gelb Icahn School of Medicine at Mount Sinai
Wendy K. Chung
Wendy K. Chung Columbia University
Barry J. Maron
Barry J. Maron University of Massachusetts Chan Medical School
Benoit G. Bruneau
Benoit G. Bruneau Gladstone Institutes
Heidi L. Rehm
Heidi L. Rehm Brigham and Women's Hospital
Alexandre C. Pereira
Alexandre C. Pereira Universidade de São Paulo

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