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Molecular Biology

D-Index
80
Citations
29588
World Ranking
986
National Ranking
522

Overview

Benoit G. Bruneau is affiliated with the Gladstone Institutes in the United States. Their research primarily focuses on topics within biochemistry, genetics, and molecular biology, with a particular emphasis on molecular biology. Their work extends to subfields including epidemiology, cardiology and cardiovascular medicine, surgery, and plant science.

Their scientific output covers a broad range of research areas. These include congenital heart defects research, genomics and chromatin dynamics, renal and related cancers, congenital heart disease studies, single-cell and spatial transcriptomics, RNA research and splicing, as well as RNA modifications and cancer.

Among their recent published papers are:

  • Cardiac natriuretic peptides, 2020, Nature Reviews Cardiology
  • Regulation of single-cell genome organization into TADs and chromatin nanodomains, 2020, Nature Genetics
  • Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation, 2020, Nature Immunology
  • Molecular basis of CTCF binding polarity in genome folding, 2020, Nature Communications
  • WAPL maintains a cohesin loading cycle to preserve cell-type-specific distal gene regulation, 2020, Nature Genetics

Frequent co-authors collaborating with Benoit G. Bruneau are:

  • Reuben Thomas
  • Katherine S. Pollard
  • Brian L. Black
  • Irfan S. Kathiriya
  • Andrew P. Blair

They have published extensively in several venues, with multiple publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Genetics
  • Nature Communications
  • Cell
  • Circulation Research

Best Publications

  • Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

    Masaki Ieda;Ji Dong Fu;Paul Delgado-Olguin;Vasanth Vedantham

  • miR-126 regulates angiogenic signaling and vascular integrity

    Jason E. Fish;Massimo M. Santoro;Sarah U. Morton;Sangho Yu

  • Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization.

    Elphège P. Nora;Anton Goloborodko;Anne-Laure Valton;Johan H. Gibcus

  • A Murine Model of Holt-Oram Syndrome Defines Roles of the T-Box Transcription Factor Tbx5 in Cardiogenesis and Disease

    Benoit G. Bruneau;Georges Nemer;Joachim P. Schmitt;Frédéric Charron

  • The developmental genetics of congenital heart disease

    Benoit G. Bruneau

  • Dynamic and Coordinated Epigenetic Regulation of Developmental Transitions in the Cardiac Lineage

    Joseph A. Wamstad;Jeffrey M. Alexander;Rebecca M. Truty;Avanti Shrikumar

  • Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

    M Bamshad;R C Lin;D J Law;W C Watkins

  • Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors.

    Jun K. Takeuchi;Benoit G. Bruneau

  • Baf60c is essential for function of BAF chromatin remodelling complexes in heart development

    Heiko Lickert;Jun K. Takeuchi;Ingo von Both;Johnathon R. Walls

  • Chamber-Specific Cardiac Expression of Tbx5 and Heart Defects in Holt–Oram Syndrome

    Benoit G. Bruneau;Malcolm Logan;Nicole Davis;Tatjana Levi;Tatjana Levi

  • Mechanical and neuroendocrine regulation of the endocrine heart

    A J de Bold;B G Bruneau;M L Kuroski de Bold

  • Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract.

    Huansheng Xu;Masae Morishima;John N. Wylie;Robert J. Schwartz

  • Single-Cell Resolution of Temporal Gene Expression during Heart Development.

    Daniel M. DeLaughter;Alexander G. Bick;Hiroko Wakimoto;David McKean

  • Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state.

    Ji Dong Fu;Nicole R. Stone;Lei Liu;C. Ian Spencer

  • Transcriptional Regulation of Vertebrate Cardiac Morphogenesis

    Benoit G. Bruneau

  • The functional landscape of mouse gene expression

    Wen-Wen Zhang;Quaid D. Morris;Richard Chang;Ofer Shai

  • Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated α-synuclein gene mutations precede central nervous system changes

    Yien-Ming Kuo;Zhishan Li;Yun Jiao;Nathalie Gaborit

  • The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage

    H. Bradley Shaffer;Patrick Minx;Daniel E. Warren;Andrew M. Shedlock;Andrew M. Shedlock

  • Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart.

    Fiona A Stennard;Mauro W Costa;David Anthony Elliott;Scott Rankin

  • Regulation of Chamber-Specific Gene Expression in the Developing Heart by Irx4

    Zheng-Zheng Bao;Benoit G. Bruneau;J. G. Seidman;Christine E. Seidman

Frequent Co-Authors

Christine E. Seidman
Christine E. Seidman Harvard University
Jonathan G. Seidman
Jonathan G. Seidman Harvard University
Katherine S. Pollard
Katherine S. Pollard University of California, San Francisco
Deepak Srivastava
Deepak Srivastava King's College London
Janet Rossant
Janet Rossant University of Toronto
Brian L. Black
Brian L. Black University of California, San Francisco
Didier Y. R. Stainier
Didier Y. R. Stainier Max Planck Society
Peter H. Backx
Peter H. Backx York University
Len A. Pennacchio
Len A. Pennacchio Lawrence Berkeley National Laboratory
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco

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