The scientist’s investigation covers issues in Cell biology, Heart development, Genetics, Transcription factor and Endocrinology. His Cell biology research includes themes of Embryonic stem cell, MEF2C, Lateral plate mesoderm and Cellular differentiation. His studies in Cellular differentiation integrate themes in fields like Myocyte, Chromatin, Epigenetics and Computational biology.
His work deals with themes such as Ventricle, Anatomy, Heart disease and Bioinformatics, which intersect with Heart development. The Transcription factor study combines topics in areas such as Heterochromatin, Heart formation and TBX20. His work focuses on many connections between Endocrinology and other disciplines, such as Internal medicine, that overlap with his field of interest in Repressor and Cardiology.
Benoit G. Bruneau mostly deals with Cell biology, Transcription factor, Heart development, Genetics and Gene expression. His Cell biology study combines topics in areas such as Cellular differentiation, CTCF, Chromatin, Regulation of gene expression and Transcription. His research in Regulation of gene expression intersects with topics in Molecular biology, Epigenetics and Heart failure.
The study incorporates disciplines such as Internal medicine, Haploinsufficiency and Endocrinology in addition to Transcription factor. His studies deal with areas such as Cardiovascular physiology, Anatomy, Heart disease, Neuroscience and Gene regulatory network as well as Heart development. His Heart disease research includes elements of Disease and Bioinformatics.
Benoit G. Bruneau spends much of his time researching Cell biology, CTCF, Transcription factor, Gene and Chromatin. His Cell biology study integrates concerns from other disciplines, such as Neurodegeneration, Cohesin, Enhancer, Transcription and Regulation of gene expression. He combines subjects such as Heart failure, Ventricular remodeling and Heart development with his study of Regulation of gene expression.
His research integrates issues of Phenotype, Computational biology and DNA in his study of Transcription factor. He interconnects Adaptation, Monitor lizard and Heart disease in the investigation of issues within Gene. His Chromatin research is multidisciplinary, relying on both Genome, Genomic organization, Gene expression and Cellular differentiation.
His main research concerns Cell biology, CTCF, Genomic organization, DNA and Chromatin. The study incorporates disciplines such as Innate immune system, Neuroinflammation and Neuroprotection in addition to Cell biology. His CTCF study contributes to a more complete understanding of Transcription.
His Genomic organization study combines topics in areas such as Cellular differentiation, Protein domain, Cohesin, Zinc finger and Nucleosome. His work carried out in the field of DNA brings together such families of science as DNA-binding protein and Protein family. Many of his studies involve connections with topics such as RNA and Chromatin.
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Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors
Masaki Ieda;Ji Dong Fu;Paul Delgado-Olguin;Vasanth Vedantham.
miR-126 Regulates Angiogenic Signaling and Vascular Integrity
Jason E. Fish;Massimo M. Santoro;Sarah U. Morton;Sangho Yu.
Developmental Cell (2008)
A Murine Model of Holt-Oram Syndrome Defines Roles of the T-Box Transcription Factor Tbx5 in Cardiogenesis and Disease
Benoit G. Bruneau;Georges Nemer;Joachim P. Schmitt;Frédéric Charron.
The developmental genetics of congenital heart disease
Benoit G. Bruneau.
Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization.
Elphège P. Nora;Anton Goloborodko;Anne-Laure Valton;Johan H. Gibcus.
Dynamic and Coordinated Epigenetic Regulation of Developmental Transitions in the Cardiac Lineage
Joseph A. Wamstad;Jeffrey M. Alexander;Rebecca M. Truty;Avanti Shrikumar.
Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome
Bamshad M;Lin Rc;Law Dj;Watkins Wc.
Nature Genetics (1997)
Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors.
Jun K. Takeuchi;Benoit G. Bruneau.
Baf60c is essential for function of BAF chromatin remodelling complexes in heart development
Heiko Lickert;Jun K. Takeuchi;Ingo von Both;Johnathon R. Walls.
Chamber-Specific Cardiac Expression of Tbx5 and Heart Defects in Holt–Oram Syndrome
Benoit G. Bruneau;Malcolm Logan;Nicole Davis;Tatjana Levi;Tatjana Levi.
Developmental Biology (1999)
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