D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 110 Citations 52,147 227 World Ranking 297 National Ranking 185

Research.com Recognitions

Awards & Achievements

2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Mutation

His scientific interests lie mostly in Genetics, Enhancer, Gene, Genome and Human genome. Genetics and Apolipoprotein B are commonly linked in his work. His Enhancer research incorporates themes from Regulation of gene expression, Reporter gene and Conserved sequence.

Len A. Pennacchio combines subjects such as Computational biology and Binding site with his study of Gene. His Genome study incorporates themes from Homeobox and Hox gene. His Human genome study combines topics from a wide range of disciplines, such as Disease and Genomics.

His most cited work include:

  • Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease (1951 citations)
  • Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease (1951 citations)
  • ChIP-seq accurately predicts tissue-specific activity of enhancers (1335 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Genetics, Gene, Enhancer, Computational biology and Regulation of gene expression. Genetics is a component of his Human genome, Allele, Transgene, Regulatory sequence and Mutation studies. His studies in Allele integrate themes in fields like Internal medicine, Single-nucleotide polymorphism, Genetic association and Genetic variation.

The various areas that Len A. Pennacchio examines in his Enhancer study include Chromatin, Epigenomics, Conserved sequence and Cell biology. His biological study spans a wide range of topics, including Genome, Genomics, Function, Sequence and DNA sequencing. Len A. Pennacchio has included themes like Enhancer RNAs, Histone and Gene expression profiling in his Regulation of gene expression study.

He most often published in these fields:

  • Genetics (93.85%)
  • Gene (68.16%)
  • Enhancer (75.42%)

What were the highlights of his more recent work (between 2018-2021)?

  • Enhancer (75.42%)
  • Gene (68.16%)
  • Transcription factor (26.26%)

In recent papers he was focusing on the following fields of study:

Len A. Pennacchio mostly deals with Enhancer, Gene, Transcription factor, Chromatin and Cell biology. Len A. Pennacchio studied Enhancer and Histone that intersect with Epigenome. His Gene research entails a greater understanding of Genetics.

His Transcription factor research includes themes of Gene knockout, Epigenomics, Penetrance and Cardiac neural crest cells. His Chromatin study integrates concerns from other disciplines, such as Sinoatrial node, Gene expression, DNA methylation and Computational biology. Len A. Pennacchio has researched Computational biology in several fields, including ENCODE, Epigenetics and Genome.

Between 2018 and 2021, his most popular works were:

  • Expanded encyclopaedias of DNA elements in the human and mouse genomes (141 citations)
  • Expanded encyclopaedias of DNA elements in the human and mouse genomes (141 citations)
  • An atlas of dynamic chromatin landscapes in mouse fetal development. (37 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Mutation

His primary areas of investigation include Enhancer, Chromatin, Computational biology, Regulation of gene expression and Gene. His Enhancer research includes elements of Mutation, Sonic hedgehog, Reporter gene, Cell biology and Genome editing. In his study, Methylation, Genomics and Functional genomics is strongly linked to DNA methylation, which falls under the umbrella field of Chromatin.

The Computational biology study combines topics in areas such as Transcription factor, Epigenomics, ENCODE and Promoter. His study looks at the relationship between Regulation of gene expression and fields such as Histone, as well as how they intersect with chemical problems. His biological study focuses on CRISPR.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

Stefano Romeo;Julia Kozlitina;Julia Kozlitina;Chao Xing;Alexander Pertsemlidis.
Nature Genetics (2008)

2182 Citations

The amphioxus genome and the evolution of the chordate karyotype

Nicholas H. Putnam;Nicholas H. Putnam;Thomas Butts;David E. K. Ferrier;Rebecca F. Furlong.
Nature (2008)

2022 Citations

ChIP-seq accurately predicts tissue-specific activity of enhancers

Axel Visel;Matthew J. Blow;Matthew J. Blow;Zirong Li;Tao Zhang.
Nature (2009)

1700 Citations

Metagenomic discovery of biomass-degrading genes and genomes from cow rumen.

Matthias Hess;Matthias Hess;Alexander Sczyrba;Alexander Sczyrba;Rob Egan;Rob Egan;Tae Wan Kim.
Science (2011)

1205 Citations

In vivo enhancer analysis of human conserved non-coding sequences

Len A. Pennacchio;Len A. Pennacchio;Nadav Ahituv;Alan M. Moses;Shyam Prabhakar.
Nature (2006)

1194 Citations

An Apolipoprotein Influencing Triglycerides in Humans and Mice Revealed by Comparative Sequencing

Len A. Pennacchio;Michael Olivier;Jaroslav A. Hubacek;Jonathan C. Cohen.
Science (2001)

1193 Citations

Guidelines for investigating causality of sequence variants in human disease

D G MacArthur;T A Manolio;D P Dimmock;H L Rehm.
Nature (2014)

1039 Citations

VISTA Enhancer Browser—a database of tissue-specific human enhancers

Axel Visel;Simon Minovitsky;Inna Dubchak;Inna Dubchak;Len A. Pennacchio;Len A. Pennacchio.
Nucleic Acids Research (2007)

907 Citations

Dicer, Drosha, and outcomes in patients with ovarian cancer

William M. Merritt;Yvonne G. Lin;Liz Y. Han;Aparna A. Kamat.
The New England Journal of Medicine (2008)

798 Citations

A common allele on chromosome 9 associated with coronary heart disease

Ruth Mcpherson;Alexander Pertsemlidis;Nihan Kavaslar;Alexandre Stewart.
Obstetrical & Gynecological Survey (2007)

677 Citations

Best Scientists Citing Len A. Pennacchio

Stefano Romeo

Stefano Romeo

University of Gothenburg

Publications: 120

Sekar Kathiresan

Sekar Kathiresan

Harvard University

Publications: 99

Luca Valenti

Luca Valenti

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Publications: 97

Eric Boerwinkle

Eric Boerwinkle

The University of Texas Health Science Center at Houston

Publications: 92

Bing Ren

Bing Ren

University of California, San Diego

Publications: 89

Mark I. McCarthy

Mark I. McCarthy

University of Oxford

Publications: 85

Axel Visel

Axel Visel

Lawrence Berkeley National Laboratory

Publications: 78

Eric S. Lander

Eric S. Lander

Office of Science and Technology Policy

Publications: 69

Jay Shendure

Jay Shendure

University of Washington

Publications: 66

Mark J. Daly

Mark J. Daly

University of Helsinki

Publications: 64

Manolis Kellis

Manolis Kellis

MIT

Publications: 62

Evan E. Eichler

Evan E. Eichler

University of Washington

Publications: 59

Jose M. Ordovas

Jose M. Ordovas

Tufts University

Publications: 59

Denis Duboule

Denis Duboule

Collège de France

Publications: 59

Boris Lenhard

Boris Lenhard

Imperial College London

Publications: 58

Ross C. Hardison

Ross C. Hardison

Pennsylvania State University

Publications: 56

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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