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Shannon J. Turley

Shannon J. Turley

D-Index & Metrics

Medicine

D-Index
84
Citations
41086
World Ranking
14843
National Ranking
7504

Overview

Shannon J. Turley is affiliated with Genentech in the United States and focuses their research within immunology, oncology, and molecular biology. Their work intersects multiple fields including immunology and microbiology, medicine, and biochemistry, genetics, and molecular biology, with a substantial number of publications reflecting expertise and ongoing contributions.

The scientist's research spans several specialized subfields such as immunology, oncology, molecular biology, cancer research, and surgery. Major thematic areas of study include immune cells in cancer, cancer immunotherapy and biomarkers, cancer cells and metastasis, immunotherapy and immune responses, single-cell and spatial transcriptomics, immune cell function and interaction, and CAR-T cell therapy research.

Among their recent papers are the following:

  • Cross-tissue organization of the fibroblast lineage, 2021, Nature
  • TGFβ biology in cancer progression and immunotherapy, 2020, Nature Reviews Clinical Oncology
  • The cancer-immunity cycle: Indication, genotype, and immunotype, 2023, Immunity
  • Fibroblasts as immune regulators in infection, inflammation and cancer, 2021, Nature Reviews Immunology
  • Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer, 2022, Cancer Cell

Frequent co-authors collaborating with Shannon J. Turley encompass:

  • Sören Müller
  • Rachana Pradhan
  • Matthew B. Buechler
  • Zora Modrušan
  • Akshay T. Krishnamurty

Key publication venues for Turley's work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Immunity
  • Nature Immunology
  • Regular and Young Investigator Award Abstracts
  • Nature

Best Publications

  • TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.

    Sanjeev Mariathasan;Shannon J. Turley;Dorothee Nickles;Alessandra Castiglioni

  • Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein

    Mark S. Anderson;Emily S. Venanzi;Ludger Klein;Zhibin Chen

  • Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

    Emmanuel L Gautier;Tal Shay;Tal Shay;Jennifer Miller;Melanie Greter

  • The Immunological Genome Project: networks of gene expression in immune cells

    Tracy S P Heng;Michio W Painter;Kutlu Elpek;Veronika Lukacs-Kornek

  • The induction of tolerance by dendritic cells that have captured apoptotic cells.

    Ralph M. Steinman;Shannon Turley;Ira Mellman;Kayo Inaba

  • Immunological hallmarks of stromal cells in the tumour microenvironment

    Shannon J. Turley;Viviana Cremasco;Viviana Cremasco;Jillian L. Astarita

  • Cross-tissue organization of the fibroblast lineage.

    Matthew B. Buechler;Rachana N. Pradhan;Akshay T. Krishnamurty;Christian Cox

  • Developmental regulation of MHC class II transport in mouse dendritic cells

    Philippe Pierre;Shannon J. Turley;Evelina Gatti;Michael Hull

  • Deciphering the transcriptional network of the dendritic cell lineage

    Jennifer C Miller;Brian D Brown;Tal Shay;Emmanuel L Gautier;Emmanuel L Gautier

  • Efficient Presentation of Phagocytosed Cellular Fragments on the Major Histocompatibility Complex Class II Products of Dendritic Cells

    Kayo Inaba;Shannon Turley;Fumiya Yamaide;Tomonori Iyoda

  • Transport of Peptide-MHC Class II Complexes in Developing Dendritic Cells

    Shannon J. Turley;Kayo Inaba;Wendy S. Garrett;Melanie Ebersold

  • TGFβ biology in cancer progression and immunotherapy.

    Rik Derynck;Shannon J. Turley;Rosemary J. Akhurst

  • Developmental Control of Endocytosis in Dendritic Cells by Cdc42

    Wendy S Garrett;Li-Mei Chen;Ruth Kroschewski;Ruth Kroschewski;Melanie Ebersold;Melanie Ebersold

  • The Formation of Immunogenic Major Histocompatibility Complex Class II-Peptide Ligands in Lysosomal Compartments of Dendritic Cells Is Regulated by Inflammatory Stimuli

    Kayo Inaba;Shannon J. Turley;Tomonori Iyoda;Fumiya Yamaide

  • Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy

    Claudia X. Dominguez;Sören Müller;Shilpa Keerthivasan;Hartmut Koeppen

  • Th17 Cells Induce Ectopic Lymphoid Follicles in Central Nervous System Tissue Inflammation

    Anneli Peters;Lisa A. Pitcher;Jenna M. Sullivan;Meike Mitsdoerffer

  • Physiological β Cell Death Triggers Priming of Self-reactive T Cells by Dendritic Cells in a Type-1 Diabetes Model

    Shannon Turley;Laurent Poirot;Masakazu Hattori;Christophe Benoist

  • Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks

    Deepali Malhotra;Anne L Fletcher;Jillian Astarita;Veronika Lukacs-Kornek

  • Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self.

    Je-Wook Lee;Mathieu Epardaud;Mathieu Epardaud;Jing Sun;Jessica E Becker

  • Podoplanin: emerging functions in development, the immune system, and cancer

    Jillian Leigh Astarita;Sophie E Acton;Sophie E Acton;Shannon J Turley

Frequent Co-Authors

Michael C. Carroll
Michael C. Carroll Boston Children's Hospital
Ananda W. Goldrath
Ananda W. Goldrath University of California, San Diego
Miriam Merad
Miriam Merad Icahn School of Medicine at Mount Sinai
Gwendalyn J. Randolph
Gwendalyn J. Randolph Washington University in St. Louis
Michael B. Brenner
Michael B. Brenner Harvard Medical School
Kai W. Wucherpfennig
Kai W. Wucherpfennig Harvard University
Amy J. Wagers
Amy J. Wagers Harvard University
Brian D. Brown
Brian D. Brown Icahn School of Medicine at Mount Sinai
Daphne Koller
Daphne Koller insitro Inc.
Diane Mathis
Diane Mathis Harvard University

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