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Immunology

D-Index
75
Citations
27718
World Ranking
1958
National Ranking
959

Research.com Recognitions

  • 2006 - Hellman Fellow

Overview

Ananda W. Goldrath is affiliated with the University of California, San Diego in the United States. Their research primarily focuses on immunology and microbiology, with significant contributions in medicine. Their work spans several key subfields including immunology, molecular biology, oncology, hematology, and cancer research.

Goldrath's research topics encompass:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Single-cell and spatial transcriptomics
  • Immunotherapy and Immune Responses
  • Cancer Immunotherapy and Biomarkers
  • Immune cells in cancer
  • CAR-T cell therapy research

They have a strong publication record with frequent contributions to venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Immunology
  • Regular and Young Investigator Award Abstracts
  • Nature Immunology
  • Immunity

Recent notable papers authored or coauthored by Goldrath include:

  • "CD8+ T cell metabolism in infection and cancer," 2021, Nature Reviews Immunology
  • "The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments," 2021, Nature Communications
  • "Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy," 2020, Immunity
  • "Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses," 2020, Science Immunology
  • "Early precursors and molecular determinants of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing," 2020, Science Immunology

Frequent collaborators in their research include Maximilian Heeg, J. Justin Milner, John T. Chang, Kyla Omilusik, and Sara Quon, with publications coauthored consistently over time.

Ananda W. Goldrath received the Hellman Fellow award in 2006, recognizing their contributions in the field. Their work engages deeply with immune cell biology, particularly exploring the dynamics of T cell populations, their metabolism, and their roles in infection, cancer, and immunotherapy contexts.

Best Publications

  • The Immunological Genome Project: networks of gene expression in immune cells

    Tracy S P Heng;Michio W Painter;Kutlu Elpek;Veronika Lukacs-Kornek

  • Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

    Laurel A Monticelli;Gregory F Sonnenberg;Michael C Abt;Theresa Alenghat

  • Effector and memory CD8 + T cell fate coupled by T-bet and eomesodermin

    Andrew M Intlekofer;Naofumi Takemoto;E John Wherry;E John Wherry;Sarah A Longworth

  • HIF Transcription Factors, Inflammation, and Immunity

    Asis Palazon;Ananda W. Goldrath;Victor Nizet;Victor Nizet;Randall S. Johnson;Randall S. Johnson

  • Selecting and maintaining a diverse T-cell repertoire

    Ananda W. Goldrath;Michael J. Bevan

  • Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation.

    Ananda W. Goldrath;Lisa Y. Bogatzki;Michael J. Bevan

  • Cytokine Requirements for Acute and Basal Homeostatic Proliferation of Naive and Memory CD8+ T Cells

    Ananda W. Goldrath;Pallavur V. Sivakumar;Moira Glaccum;Mary K. Kennedy

  • Macrophage Expression of Hypoxia-Inducible Factor-1α Suppresses T-Cell Function and Promotes Tumor Progression

    Andrew L. Doedens;Christian Stockmann;Mark P. Rubinstein;Debbie Liao

  • Hypoxia-inducible factors enhance the effector responses of CD8 + T cells to persistent antigen

    Andrew L Doedens;Anthony T Phan;Martin H Stradner;Martin H Stradner;Jessica K Fujimoto

  • Runx3 programs CD8 + T cell residency in non-lymphoid tissues and tumours

    J. Justin Milner;Clara Toma;Bingfei Yu;Kai Zhang

  • Low-Affinity Ligands for the TCR Drive Proliferation of Mature CD8+ T Cells in Lymphopenic Hosts

    Ananda W Goldrath;Michael J Bevan

  • Molecular regulation of effector and memory T cell differentiation

    John T Chang;E John Wherry;Ananda W Goldrath

  • Selecting and maintaining a diverse T-cell repertoire

    Unknown

  • CD8 + T cell metabolism in infection and cancer

    Miguel Reina-Campos;Nicole E. Scharping;Ananda W. Goldrath

  • An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression

    Asis Palazon;Petros A. Tyrakis;David Macias;Pedro Veliça

  • The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets.

    Cliff Y Yang;J Adam Best;Jamie Knell;Edward Yang

  • S -2-hydroxyglutarate regulates CD8 + T-lymphocyte fate

    Petros A. Tyrakis;Asis Palazon;David Macias;Kian. L. Lee

  • Transcriptional insights into the CD8+ T cell response to infection and memory T cell formation

    J Adam Best;David A Blair;Jamie Knell;Edward Yang

  • FOXO transcription factors throughout T cell biology

    Stephen M. Hedrick;Rodrigo Hess Michelini;Andrew L. Doedens;Ananda W. Goldrath

  • Virus-mediated delivery of antigenic epitopes into dendritic cells as a means to induce CTL.

    Peter Brossart;Ananda W. Goldrath;Eric A. Butz;Stefan Martin

  • Expression profiling of constitutive mast cells reveals a unique identity within the immune system

    Daniel F Dwyer;Daniel F Dwyer;Nora A Barrett;Nora A Barrett;K Frank Austen;K Frank Austen

Frequent Co-Authors

John T. Chang
John T. Chang University of California, San Diego
Shane Crotty
Shane Crotty La Jolla Institute For Allergy & Immunology
Randall S. Johnson
Randall S. Johnson University of Cambridge
Diane Mathis
Diane Mathis Harvard University
Christophe Benoist
Christophe Benoist Harvard University
Stephen M. Hedrick
Stephen M. Hedrick University of California, San Diego
E. John Wherry
E. John Wherry University of Pennsylvania
Michael J. Bevan
Michael J. Bevan University of Washington
Gene W. Yeo
Gene W. Yeo University of California, San Diego

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