John T. Chang

Best Publications

• Pathophysiology of Inflammatory Bowel Diseases

  Unknown

  1166
  Citations

• Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

  John T. Chang;Vikram R. Palanivel;Ichiko Kinjyo;Felix Schambach

  1061
  Citations

• A gp130-Src-YAP Module Links Inflammation to Epithelial Regeneration

  Koji Taniguchi;Koji Taniguchi;Koji Taniguchi;Li Wha Wu;Li Wha Wu;Sergei I. Grivennikov;Sergei I. Grivennikov;Petrus R. De Jong

  657
  Citations

• Molecular regulation of effector and memory T cell differentiation

  John T Chang;E John Wherry;Ananda W Goldrath

  653
  Citations

• Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy.

  J. Justin Milner;Clara Toma;Zhaoren He;Nadia S. Kurd

  271
  Citations

• Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses

  Brigid S. Boland;Zhaoren He;Matthew S. Tsai;Jocelyn G. Olvera

  260
  Citations

• Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing

  Boyko Kakaradov;Janilyn Arsenio;Christella E Widjaja;Zhaoren He

  259
  Citations

• Epigenetic landscapes reveal transcription factors that regulate CD8 + T cell differentiation

  Bingfei Yu;Kai Zhang;J Justin Milner;Clara Toma

  253
  Citations

• Asymmetric Proteasome Segregation as a Mechanism for Unequal Partitioning of the Transcription Factor T-bet during T Lymphocyte Division

  John T. Chang;Maria L. Ciocca;Ichiko Kinjyo;Vikram R. Palanivel

  249
  Citations

• Early specification of CD8+ T lymphocyte fates during adaptive immunity revealed by single-cell gene-expression analyses

  Janilyn Arsenio;Boyko Kakaradov;Patrick J Metz;Stephanie H Kim

  243
  Citations

• CpG Oligonucleotides Are Potent Adjuvants for the Activation of Autoreactive Encephalitogenic T Cells In Vivo

  Benjamin M. Segal;John T. Chang;John T. Chang;Ethan M. Shevach

  234
  Citations

• The costimulatory effect of IL-18 on the induction of antigen-specific IFN-γ production by resting T cells is IL-12 dependent and is mediated by up-regulation of the IL-12 receptor β2 subunit

  John T. Chang;Benjamin M. Segal;Kenji Nakanishi;Haruki Okamura

  230
  Citations

• Tissue-resident memory CD8+ T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments

  Unknown

  216
  Citations

• Early precursors and molecular determinants of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing

  Nadia S. Kurd;Zhaoren He;Tiani L. Louis;J. Justin Milner

  207
  Citations

• Requirements for the Maintenance of Th1 Immunity In Vivo Following DNA Vaccination: A Potential Immunoregulatory Role for CD8+ T Cells

  S Gurunathan;L Stobie;C Prussin;D L Sacks

  184
  Citations

• Inducible MHC class II expression by mast cells supports effector and regulatory T cell activation.

  Taku Kambayashi;Eric J. Allenspach;John T. Chang;Tao Zou

  174
  Citations

• Asymmetric Cell Division of T Cells upon Antigen Presentation Uses Multiple Conserved Mechanisms

  Jane Oliaro;Vanessa Van Ham;Faruk Sacirbegovic;Anupama Pasam

  159
  Citations

• Regulation of Interleukin (IL)-12 Receptor β2 Subunit Expression by Endogenous IL-12: A Critical Step in the Differentiation of Pathogenic Autoreactive T Cells

  John T. Chang;Ethan M. Shevach;Benjamin M. Segal

  145
  Citations

• Elevated A20 promotes TNF-induced and RIPK1-dependent intestinal epithelial cell death.

  Ricard Garcia-Carbonell;Jerry Wong;Ju Youn Kim;Lisa Abernathy Close

  135
  Citations

• The TRPA1 ion channel is expressed in CD4+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1

  Samuel Bertin;Yukari Aoki-Nonaka;Yukari Aoki-Nonaka;Jihyung Lee;Petrus R de Jong

  130
  Citations