2026 Susan M. Kaech: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	95	875	797	487	436	240	49418
Medicine	95	9877	9267	5081	4694	242	49433

Research.com Recognitions

2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Susan M. Kaech is affiliated with the Salk Institute for Biological Studies in the United States and has conducted extensive research in immunology and microbiology, with a particular focus on immune responses within cancer contexts. Their work spans multiple subfields including immunology, oncology, molecular biology, cancer research, and epidemiology.

The main topics Susan M. Kaech has explored include:

Immune cells in cancer
Immune Cell Function and Interaction
T-cell and B-cell Immunology
Immunotherapy and Immune Responses
Cancer Immunotherapy and Biomarkers
CAR-T cell therapy research
Cytokine Signaling Pathways and Interactions

Major research outputs include a number of peer-reviewed papers published in prominent journals. Some recent publications are:

"Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors" (2021, Immunity)
"Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses" (2020, The Journal of Experimental Medicine)
"A Phase I Study of APX005M and Cabiralizumab with or without Nivolumab in Patients with Melanoma, Kidney Cancer, or Non-Small Cell Lung Cancer Resistant to Anti-PD-1/PD-L1" (2021, Clinical Cancer Research)
"Immunoediting instructs tumor metabolic reprogramming to support immune evasion" (2023, Cell Metabolism)
"The architectural design of CD8+ T cell responses in acute and chronic infection: Parallel structures with divergent fates" (2021, The Journal of Experimental Medicine)

Frequent co-authors collaborating with Susan M. Kaech include:

Bryan McDonald
Ziyan Xu
Siva Karthik Varanasi
Yagmur Farsakoglu
Omkar Chaudhary

Notable publication venues where they have frequently contributed are:

The Journal of Immunology
bioRxiv (Cold Spring Harbor Laboratory)
The Journal of Experimental Medicine
Cancer Research
Immunity

Susan M. Kaech's research integrates insights from immunology and oncology to better understand the functional dynamics of immune cells in cancer and related therapies. Their contributions include topics on T cell behavior, immune checkpoints, and cellular metabolism in the tumor microenvironment.

Recognition of their scientific contributions includes being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2020.

Best Publications

Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection

E. John Wherry;Sang Jun Ha;Susan M. Kaech;W. Nicholas Haining

2492
Citations
Effector and memory T-cell differentiation: implications for vaccine development

Susan M. Kaech;E. John Wherry;Rafi Ahmed

2404
Citations
Lineage relationship and protective immunity of memory CD8 T cell subsets.

E. John Wherry;Volker Teichgräber;Todd C. Becker;David Masopust

2339
Citations
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells

Susan M Kaech;Joyce T Tan;E John Wherry;Bogumila T Konieczny

2315
Citations
Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor.

Nikhil S. Joshi;Weiguo Cui;Anmol Chandele;Heung Kyu Lee

2192
Citations
Mitochondrial DNA Stress Primes the Antiviral Innate Immune Response

A. Phillip West;William Khoury-Hanold;Matthew Staron;Michal C. Tal

1845
Citations
Transcriptional control of effector and memory CD8 + T cell differentiation

Susan M. Kaech;Weiguo Cui

1807
Citations
Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells.

Susan M. Kaech;Rafi Ahmed

1645
Citations
Effector and memory CD8 + T cell fate coupled by T-bet and eomesodermin

Andrew M Intlekofer;Naofumi Takemoto;E John Wherry;E John Wherry;Sarah A Longworth

1506
Citations
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

Ping Chih Ho;Jessica Dauz Bihuniak;Andrew N. MacIntyre;Matthew Staron

1459
Citations
Molecular and Functional Profiling of Memory CD8 T Cell Differentiation

Susan M. Kaech;Scott Hemby;Ellen Kersh;Rafi Ahmed

1238
Citations
Metabolic Instruction of Immunity

Michael D. Buck;Michael D. Buck;Ryan T. Sowell;Susan M. Kaech;Erika L. Pearce

1154
Citations
Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection.

Susan M. Kaech;E. John Wherry

809
Citations
Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells

Joseph N. Blattman;Rustom Antia;David J.D. Sourdive;Xiaochi Wang

794
Citations
Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties.

Rachel L. Rutishauser;Gislâine A. Martins;Sergey Kalachikov;Anmol Chandele

750
Citations
Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes

Rachel J. Perry;João Paulo G Camporez;Romy Kursawe;Paul M. Titchenell

746
Citations
Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer

Scott Gettinger;Jungmin Choi;Katherine Hastings;Anna Truini

736
Citations
Heterologous immunity provides a potent barrier to transplantation tolerance.

Andrew B. Adams;Matthew A. Williams;Thomas R. Jones;Nozomu Shirasugi

714
Citations
The multifaceted role of CD4 + T cells in CD8 + T cell memory

Brian J. Laidlaw;Joseph E. Craft;Susan M. Kaech;Susan M. Kaech

702
Citations
Antigen-independent memory CD8 T cells do not develop during chronic viral infection.

E. John Wherry;Daniel L. Barber;Susan M. Kaech;Susan M. Kaech;Joseph N. Blattman;Joseph N. Blattman

629
Citations
Effector and memory T-cell differentiation: implications for vaccine development. Nat Rev Immunol.

SM Kaech;EJ Wherry;R Ahmed

231
Citations
Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection (DOI:10.1016/j.immuni.2007.09.006)

E. John Wherry;Sang Jun Ha;Susan M. Kaech;W. Nicholas Haining

62
Citations

Frequent Co-Authors

Rafi Ahmed Emory University

E. John Wherry University of Pennsylvania

Joe Craft Yale University

Steven H. Kleinstein Yale University

Katerina Politi Yale University

Richard A. Flavell Yale University

Kurt A. Schalper Yale University

Marcus Bosenberg Yale University

Todd R. Golub Harvard University

Roy S. Herbst Yale University

External Links

Personal website of Susan M. Kaech

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