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Immunology

D-Index
77
Citations
21909
World Ranking
1820
National Ranking
895

Medicine

D-Index
77
Citations
21909
World Ranking
18423
National Ranking
9191

Research.com Recognitions

  • 1940 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

John T. Harty is affiliated with the University of Iowa in the United States. Their research activity spans multiple areas within immunology and medicine, with a focus on immune cell function, T-cell and B-cell immunology, and neuroinflammation mechanisms.

Their main fields of study include:

  • Immunology and Microbiology
  • Medicine

More specific subfields of their research cover:

  • Immunology
  • Public Health, Environmental and Occupational Health
  • Neurology
  • Molecular Biology
  • Infectious Diseases

The primary topics addressed in their work are:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Malaria Research and Control
  • Immunotherapy and Immune Responses
  • Mosquito-borne diseases and control
  • Immune Response and Inflammation

John T. Harty has published in several venues with notable frequency. These include:

  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • Cell Reports
  • Proceedings of the National Academy of Sciences

Frequent co-authors collaborating with John T. Harty are:

  • Vladimir P. Badovinac
  • Lecia L. Pewe
  • Stephanie van de Wall
  • Mohammad Heidarian
  • Isaac J. Jensen

Selected recent papers authored or co-authored by John T. Harty include:

  • Peripherally induced brain tissue-resident memory CD8+ T cells mediate protection against CNS infection, 2020, Nature Immunology
  • Expeditious recruitment of circulating memory CD8 T cells to the liver facilitates control of malaria, 2021, Cell Reports
  • Protective function and durability of mouse lymph node-resident memory CD8+ T cells, 2021, eLife
  • Tissue resident memory T cells- A new benchmark for the induction of vaccine-induced mucosal immunity, 2022, Frontiers in Immunology
  • NK Cell-Derived IL-10 Supports Host Survival during Sepsis, 2021, The Journal of Immunology

John T. Harty was awarded the title of Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • CD8+ T cell effector mechanisms in resistance to infection.

    John T. Harty;Amy R. Tvinnereim;Douglas W. White

  • Programmed contraction of CD8(+) T cells after infection.

    Vladimir P. Badovinac;Brandon B. Porter;John T. Harty

  • Shaping and reshaping CD8+ T-cell memory.

    John T. Harty;Vladimir P. Badovinac

  • Differentiation and persistence of memory CD8+ T cells depend on T cell factor 1

    Xinyuan Zhou;Shuyang Yu;Dong-Mei Zhao;John T. Harty

  • Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection

    Noah S Butler;Jacqueline Moebius;Lecia L Pewe;Boubacar Traore

  • Regulation of Antigen-Specific CD8 + T Cell Homeostasis by Perforin and Interferon-γ

    Vladimir P. Badovinac;Amy R. Tvinnereim;John T. Harty

  • Precise prediction of a dominant class I MHC-restricted epitope of Listeria monocytogenes

    Eric G. Pamer;John T. Harty;Michael J. Bevan

  • Accelerated CD8 + T-cell memory and prime-boost response after dendritic-cell vaccination

    Vladimir P Badovinac;Kelly A N Messingham;Ali Jabbari;Jodie S Haring

  • Initial T Cell Receptor Transgenic Cell Precursor Frequency Dictates Critical Aspects of the CD8+ T Cell Response to Infection

    Vladimir P. Badovinac;Jodie S. Haring;John T. Harty

  • Specific immunity to listeria monocytogenes in the absence of IFNγ

    John T. Harty;Michael J. Bevant

  • CpG DNA Induces Sustained IL-12 Expression In Vivo and Resistance to Listeria monocytogenes Challenge

    Arthur M. Krieg;Laurie Love-Homan;Ae-Kyung Yi;John T. Harty

  • CD8+ T cell contraction is controlled by early inflammation

    Vladimir P Badovinac;Brandon B Porter;John T Harty

  • Inflaming the CD8+ T cell response.

    Jodie S. Haring;Vladimir P. Badovinac;John T. Harty

  • Repetitive Antigen Stimulation Induces Stepwise Transcriptome Diversification but Preserves a Core Signature of Memory CD8+ T Cell Differentiation

    Thomas C. Wirth;Hai-Hui Xue;Deepa Rai;Jaime T. Sabel

  • CD8+ T cells specific for a single nonamer epitope of Listeria monocytogenes are protective in vivo.

    John T. Harty;Michael J. Bevan

  • Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria.

    Nathan W. Schmidt;Rebecca L. Podyminogin;Noah S. Butler;Vladimir P. Badovinac

  • Dynamics of influenza-induced lung-resident memory T cells underlie waning heterosubtypic immunity

    Bram Slütter;Bram Slütter;Natalija Van Braeckel-Budimir;Georges Abboud;Steven M. Varga

  • Superior Antimalarial Immunity after Vaccination with Late Liver Stage-Arresting Genetically Attenuated Parasites

    Noah S. Butler;Nathan W. Schmidt;Ashley M. Vaughan;Ahmed S. Aly

  • Compartmentalization of Bacterial Antigens: Differential Effects on Priming of CD8 T Cells and Protective Immunity

    Hao Shen;Jeff F Miller;Xin Fan;David Kolwyck

  • Interactions of the Invasive Pathogens Salmonella typhimurium, Listeria monocytogenes, and Shigella flexneri with M Cells and Murine Peyer’s Patches

    V. Behrana Jensen;John T. Harty;Bradley D. Jones

  • Impaired Assembly yet Normal Trafficking of MHC Class I Molecules in Tapasin Mutant Mice

    Andres G Grandea;Tatiana N Golovina;Sara E Hamilton;Venkataraman Sriram

Frequent Co-Authors

Vladimir P. Badovinac
Vladimir P. Badovinac University of Iowa
Steven M. Varga
Steven M. Varga University of Iowa
Peter G.W. Plagemann
Peter G.W. Plagemann University of Minnesota
Michael J. Bevan
Michael J. Bevan University of Washington
Stefan H. I. Kappe
Stefan H. I. Kappe University of Washington
Thomas S. Griffith
Thomas S. Griffith University of Minnesota
Frank M. Faraci
Frank M. Faraci University of Iowa
David K. Meyerholz
David K. Meyerholz University of Iowa
Bradley D. Jones
Bradley D. Jones University of Iowa
Warren J. Leonard
Warren J. Leonard National Institutes of Health

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