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David K. Meyerholz

David K. Meyerholz

D-Index & Metrics

Microbiology

D-Index
77
Citations
26383
World Ranking
1331
National Ranking
586

Overview

David K. Meyerholz is affiliated with the University of Iowa in the United States. Their research focuses primarily on medicine, with significant contributions in the fields of infectious diseases, pulmonary and respiratory medicine, molecular biology, neurology, and epidemiology.

The scientist has contributed extensively to the study of SARS-CoV-2 and COVID-19, including clinical research and the long-term effects of COVID-19. Their research topics also include cystic fibrosis advances, neonatal respiratory health, viral gastroenteritis research and epidemiology, and tracheal and airway disorders.

Among their recent papers are:

  • COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice (2020, Nature)
  • Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment (2020, Cell)
  • 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice (2020, Science Translational Medicine)
  • Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract (2020, EBioMedicine)
  • Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19 (2022, Nature)

The scientist has collaborated frequently with several coauthors, including Stanley Perlman, Paul B. McCray, Alejandro A. Pezzulo, Jian Zheng, and Mariah Leidinger.

David K. Meyerholz has published in a variety of scientific venues, with notable numbers of publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Investigation
  • Journal of Cystic Fibrosis
  • Veterinary Pathology
  • mBio

Best Publications

  • Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

    Rudragouda Channappanavar;Anthony R. Fehr;Rahul Vijay;Matthias Mack

  • Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2.

    Jason Netland;David K. Meyerholz;Steven Moore;Martin Cassell

  • Lethal Infection of K18-hACE2 Mice Infected with Severe Acute Respiratory Syndrome Coronavirus

    Paul B. McCray;Lecia Pewe;Christine Wohlford-Lenane;Melissa Hickey

  • Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection.

    Rudragouda Channappanavar;Craig Fett;Matthias Mack;Patrick P. Ten Eyck

  • Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.

    Christopher S. Rogers;David A. Stoltz;David K. Meyerholz;Lynda S. Ostedgaard

  • Origins of Cystic Fibrosis Lung Disease

    David A. Stoltz;David K. Meyerholz;Michael J. Welsh

  • Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

    Justin P Dassie;Xiu-ying Liu;Gregory S Thomas;Ryan M Whitaker

  • Principles for Valid Histopathologic Scoring in Research

    Katherine N. Gibson-Corley;Alicia K. Olivier;David K. Meyerholz

  • IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes

    Rudragouda Channappanavar;Anthony R. Fehr;Jian Zheng;Christine Wohlford-Lenane

  • Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at Birth

    David A. Stoltz;David K. Meyerholz;Alejandro A. Pezzulo;Shyam Ramachandran

  • Airway Memory CD4+ T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses

    Jincun Zhao;Jincun Zhao;Jingxian Zhao;Ashutosh K. Mangalam;Rudragouda Channappanavar

  • Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4

    Kun Li;Christine Wohlford-Lenane;Stanley Perlman;Jincun Zhao

  • COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice.

    Jian Zheng;Lok-Yin Roy Wong;Kun Li;Abhishek Kumar Verma

  • Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment.

    Jing Sun;Zhen Zhuang;Jian Zheng;Kun Li

  • Virus-specific memory CD8 T cells provide substantial protection from lethal severe acute respiratory syndrome coronavirus infection.

    Rudragouda Channappanavar;Craig Fett;Jincun Zhao;David K. Meyerholz

  • T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus

    Andrew S Kondratowicz;Nicholas J Lennemann;Patrick L Sinn;Robert A Davey

  • Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis

    Xingshen Sun;Hongshu Sui;John T. Fisher;Ziying Yan

  • Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae

    Barry R. O'Keefe;Barbara Giomarelli;Dale L. Barnard;Shilpa R. Shenoy

  • Airway acidification initiates host defense abnormalities in cystic fibrosis mice

    Viral S. Shah;Viral S. Shah;David K. Meyerholz;Xiao Xiao Tang;Xiao Xiao Tang;Leah Reznikov

  • The porcine lung as a potential model for cystic fibrosis.

    Christopher S. Rogers;William M. Abraham;Kim A. Brogden;John F. Engelhardt

  • Foxp3+ CD4 Regulatory T Cells Limit Pulmonary Immunopathology by Modulating the CD8 T Cell Response during Respiratory Syncytial Virus Infection

    Ross B. Fulton;David K. Meyerholz;Steven M. Varga

Frequent Co-Authors

David A. Stoltz
David A. Stoltz University of Iowa
Paul B. McCray
Paul B. McCray University of Iowa
Michael J. Welsh
Michael J. Welsh University of Iowa
Stanley Perlman
Stanley Perlman University of Iowa
Joseph Zabner
Joseph Zabner University of Iowa
Steven M. Varga
Steven M. Varga University of Iowa
Jincun Zhao
Jincun Zhao Guangzhou Medical University
Rajesh Khanna
Rajesh Khanna University of Florida
John F. Engelhardt
John F. Engelhardt University of Iowa
Randall S. Prather
Randall S. Prather University of Missouri

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