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Molecular Biology

D-Index
86
Citations
29518
World Ranking
820
National Ranking
432

Overview

Joseph Zabner is affiliated with the University of Iowa in the United States and has made significant contributions to the field of pulmonary and respiratory medicine. Their research covers a broad spectrum of topics within medicine, particularly focusing on respiratory health and diseases.

Their main fields of study include Medicine, with specialized focus on Pulmonary and Respiratory Medicine, Physiology, Molecular Biology, Endocrine and Autonomic Systems, and Cardiology and Cardiovascular Medicine.

Zabner's research interests are reflected in their work on several key topics:

  • Cystic Fibrosis Research Advances
  • Neonatal Respiratory Health Research
  • Tracheal and Airway Disorders
  • Asthma and Respiratory Diseases
  • Inhalation and Respiratory Drug Delivery
  • Long-Term Effects of COVID-19
  • COVID-19 Clinical Research Studies

Some of their recent publications include:

  • Quantitative Chest CT Assessment of Small Airways Disease in Post-Acute SARS-CoV-2 Infection (2022), published in Radiology
  • CFTR-rich ionocytes mediate chloride absorption across airway epithelia (2023), published in Journal of Clinical Investigation
  • V-Type ATPase Mediates Airway Surface Liquid Acidification in Pig Small Airway Epithelial Cells (2021), published in American Journal of Respiratory Cell and Molecular Biology
  • Chronic obstructive pulmonary disease (COPD) and COPD-like phenotypes (2024), published in Frontiers in Medicine
  • Disruption of the circadian rhythm of melatonin: A biomarker of critical illness severity (2023), published in Sleep Medicine

Zabner frequently collaborates with other researchers, including:

  • David A. Stoltz
  • Alejandro A. Pezzulo
  • Alejandro P. Comellas
  • Ian M. Thornell
  • Raul Villacreses

The scientist's work has been published repeatedly in several venues such as bioRxiv (Cold Spring Harbor Laboratory), Journal of Cystic Fibrosis, American Journal of Physiology-Lung Cellular and Molecular Physiology, American Journal of Respiratory Cell and Molecular Biology, and Radiology.

Best Publications

  • TLR4 mutations are associated with endotoxin hyporesponsiveness in humans.

    Nancy C. Arbour;Eva Lorenz;Brian C. Schutte;Joseph Zabner

  • Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid

    Joseph Zabner;Al J. Fasbender;Tom Moninger;Kristi A. Poellinger

  • Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung

    Alejandro A. Pezzulo;Xiao Xiao Tang;Mark J. Hoegger;Mahmoud H. Abou Alaiwa

  • Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.

    Christopher S. Rogers;David A. Stoltz;David K. Meyerholz;Lynda S. Ostedgaard

  • Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system

    Beverly L. Davidson;Colleen S. Stein;Jason A. Heth;Inês Martins

  • Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis

    Joseph Zabner;Larry A. Couture;Richard J. Gregory;Scott M. Graham

  • Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at Birth

    David A. Stoltz;David K. Meyerholz;Alejandro A. Pezzulo;Shyam Ramachandran

  • Adeno-Associated Virus Serotype 4 (AAV4) and AAV5 Both Require Sialic Acid Binding for Hemagglutination and Efficient Transduction but Differ in Sialic Acid Linkage Specificity

    Nikola Kaludov;Kevin E. Brown;Robert W. Walters;Joseph Zabner

  • Adenovirus Fiber Disrupts CAR-Mediated Intercellular Adhesion Allowing Virus Escape

    Robert W. Walters;Robert W. Walters;Paul Freimuth;Thomas O. Moninger;Thomas O. Moninger;Ingrid Ganske

  • An In Vitro Model of Differentiated Human Airway Epithelia

    Philip H. Karp;Thomas O. Moninger;S. Pary Weber;Tamara S. Nesselhauf

  • Basolateral localization of fiber receptors limits adenovirus infection from the apical surface of airway epithelia.

    Robert W. Walters;Teresa Grunst;Jeffrey M. Bergelson;Robert W. Finberg

  • Binding of adeno-associated virus type 5 to 2,3-linked sialic acid is required for gene transfer.

    Robert W. Walters;Su Min P. Yi;Shaf Keshavjee;Kevin E. Brown

  • Segregation of receptor and ligand regulates activation of epithelial growth factor receptor

    Paola D. Vermeer;Lisa A. Einwalter;Thomas O. Moninger;Tatiana Rokhlina

  • Adeno-Associated Virus Type 5 (AAV5) but Not AAV2 Binds to the Apical Surfaces of Airway Epithelia and Facilitates Gene Transfer

    Joseph Zabner;Michael Seiler;Robert Walters;Robert M. Kotin

  • Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis

    Mark J. Hoegger;Anthony J. Fischer;James D. McMenimen;Lynda S. Ostedgaard

  • The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia

    Alejandro Antonio Pezzulo;Timothy D. Starner;Todd E. Scheetz;Geri L. Traver

  • Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia

    Carlene K. Chun;Egon A. Ozer;Michael J. Welsh;Joseph Zabner

  • Practical reconstruction method for bioluminescence tomography

    Wenxiang Cong;Ge Wang;Durairaj Kumar;Yi Liu

  • Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats

    Joseph Zabner;Deanna M. Petersen;Aurita P. Puga;Scott M. Graham

  • Loss of CFTR Chloride Channels Alters Salt Absorption by Cystic Fibrosis Airway Epithelia In Vitro

    Joseph Zabner;Jeffrey J Smith;Philip H Karp;Jonathan H Widdicombe

Frequent Co-Authors

Michael J. Welsh
Michael J. Welsh University of Iowa
David A. Stoltz
David A. Stoltz University of Iowa
Paul B. McCray
Paul B. McCray University of Iowa
David K. Meyerholz
David K. Meyerholz University of Iowa
Beverly L. Davidson
Beverly L. Davidson Children's Hospital of Philadelphia
Alan E. Smith
Alan E. Smith Sanofi (United States)
Eric A. Hoffman
Eric A. Hoffman University of Iowa
Shaf Keshavjee
Shaf Keshavjee University Health Network
John A. Chiorini
John A. Chiorini National Institutes of Health
Randall S. Prather
Randall S. Prather University of Missouri

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