What is he best known for?
The fields of study he is best known for:
Alan E. Smith spends much of his time researching Cystic fibrosis transmembrane conductance regulator, Cystic fibrosis, Molecular biology, Chloride channel and Internal medicine.
His research integrates issues of Mutation, Mutant, Membrane protein and Cell biology in his study of Cystic fibrosis transmembrane conductance regulator.
Alan E. Smith works mostly in the field of Cell biology, limiting it down to topics relating to ΔF508 and, in certain cases, Mutant protein and Intracellular.
The concepts of his Cystic fibrosis study are interwoven with issues in Immunology, Transfection, Pathology, Complementary DNA and Lung.
His Molecular biology research incorporates elements of Adenoviridae, Genetic transfer, Genetic enhancement, Capsid and Peptide sequence.
His work is dedicated to discovering how Internal medicine, Endocrinology are connected with Transepithelial potential difference and other disciplines.
His most cited work include:
- A short amino acid sequence able to specify nuclear location (2161 citations)
- Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis (1538 citations)
- Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis (1193 citations)
What are the main themes of his work throughout his whole career to date?
Molecular biology, Cystic fibrosis transmembrane conductance regulator, Cystic fibrosis, Biochemistry and Cell biology are his primary areas of study.
His Molecular biology research incorporates themes from Mutation, Mutant, DNA, Antigen and Virus.
His Cystic fibrosis transmembrane conductance regulator study combines topics from a wide range of disciplines, such as Chloride channel and Membrane protein.
His studies in Chloride channel integrate themes in fields like Apical membrane and Chinese hamster ovary cell.
His Cystic fibrosis research includes themes of Immunology, Pathology, Complementary DNA, Genetic enhancement and Lung.
He does research in Cell biology, focusing on Intracellular specifically.
He most often published in these fields:
- Molecular biology (42.54%)
- Cystic fibrosis transmembrane conductance regulator (25.97%)
- Cystic fibrosis (23.20%)
What were the highlights of his more recent work (between 1994-2016)?
- Cystic fibrosis (23.20%)
- Cystic fibrosis transmembrane conductance regulator (25.97%)
- Flora (7.73%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Cystic fibrosis, Cystic fibrosis transmembrane conductance regulator, Flora, Moss and Viral vector.
His research in Cystic fibrosis intersects with topics in Lung, Gene and Pathology.
His Cystic fibrosis transmembrane conductance regulator research integrates issues from Molecular biology, Transfection and Binding site.
Alan E. Smith has included themes like Cell culture, Mutant, Complementary DNA, Chloride channel and In vivo in his Molecular biology study.
His study in Viral vector is interdisciplinary in nature, drawing from both Lung disease, Genetic enhancement, Transgene and Cell biology.
While the research belongs to areas of Internal medicine, Alan E. Smith spends his time largely on the problem of Endocrinology, intersecting his research to questions surrounding Regulator, Chloride channel activity and Biological activity.
Between 1994 and 2016, his most popular works were:
- Detailed Analysis of Structures and Formulations of Cationic Lipids for Efficient Gene Transfer to the Lung (425 citations)
- Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: a double-blind placebo-controlled trial. (394 citations)
- PEGylation of Adenovirus with Retention of Infectivity and Protection from Neutralizing Antibody in Vitro and in Vivo (354 citations)
In his most recent research, the most cited papers focused on:
His primary areas of investigation include Genetic enhancement, Molecular biology, Cystic fibrosis, Vector and Cystic fibrosis transmembrane conductance regulator.
His Genetic enhancement research is multidisciplinary, incorporating elements of Immunology and Virology.
His Molecular biology study integrates concerns from other disciplines, such as Transgene and In vivo.
Alan E. Smith has researched Cystic fibrosis in several fields, including Gene, Lung and Pathology.
His Vector study deals with Gene transfer intersecting with Open reading frame, Chromatography, Disease and Lysosomal storage disorders.
His Cystic fibrosis transmembrane conductance regulator study is associated with Internal medicine.
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