What is she best known for?
The fields of study she is best known for:
The scientist’s investigation covers issues in Cystic fibrosis transmembrane conductance regulator, Cystic fibrosis, Cell biology, Mutation and Endoplasmic reticulum.
Her Cystic fibrosis transmembrane conductance regulator research is multidisciplinary, incorporating perspectives in Molecular biology, Clinical trial, Surrogate endpoint and Transmembrane protein.
Her Cystic fibrosis research entails a greater understanding of Internal medicine.
Her Cell biology study incorporates themes from Proteome, Biochemistry, Caenorhabditis elegans and Genetic screen.
Her work deals with themes such as Apical membrane and Protein folding, which intersect with Endoplasmic reticulum.
Margarida D. Amaral has included themes like Disease and Allelic heterogeneity in her Genotype study.
Her most cited work include:
- Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene (390 citations)
- Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene (390 citations)
- Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei (238 citations)
What are the main themes of her work throughout her whole career to date?
Margarida D. Amaral mainly investigates Cystic fibrosis, Cystic fibrosis transmembrane conductance regulator, Cell biology, Molecular biology and Endoplasmic reticulum.
Her Cystic fibrosis study is focused on Internal medicine in general.
While the research belongs to areas of Internal medicine, Margarida D. Amaral spends her time largely on the problem of Endocrinology, intersecting her research to questions surrounding Genotype-phenotype distinction.
Her Cystic fibrosis transmembrane conductance regulator research is classified as research in Genetics.
Her Cell biology research is multidisciplinary, incorporating elements of Regulator, Biochemistry and Transmembrane protein.
Margarida D. Amaral has researched Endoplasmic reticulum in several fields, including Chaperone and Protein folding.
She most often published in these fields:
- Cystic fibrosis (61.32%)
- Cystic fibrosis transmembrane conductance regulator (46.23%)
- Cell biology (37.26%)
What were the highlights of her more recent work (between 2017-2021)?
- Cystic fibrosis (61.32%)
- Cell biology (37.26%)
- Cystic fibrosis transmembrane conductance regulator (46.23%)
In recent papers she was focusing on the following fields of study:
Her primary areas of investigation include Cystic fibrosis, Cell biology, Cystic fibrosis transmembrane conductance regulator, Mutation and Chloride channel.
Her Cystic fibrosis study improves the overall literature in Internal medicine.
Her work carried out in the field of Cell biology brings together such families of science as Regulator, Transcription factor and Mutant.
Margarida D. Amaral has researched Cystic fibrosis transmembrane conductance regulator in several fields, including Cancer and Respiratory tree.
Margarida D. Amaral works mostly in the field of Mutation, limiting it down to topics relating to Messenger RNA and, in certain cases, Western blot and Nonsense-mediated decay.
Her Chloride channel research includes themes of Secretion, Signal transduction and Actin cytoskeleton.
Between 2017 and 2021, her most popular works were:
- “CFTR Modulator Theratyping: Current Status, Gaps and Future Directions” (82 citations)
- Compartmentalized crosstalk of CFTR and TMEM16A (ANO1) through EPAC1 and ADCY1 (20 citations)
- R560S: A class II CFTR mutation that is not rescued by current modulators. (15 citations)
In her most recent research, the most cited papers focused on:
Margarida D. Amaral mainly investigates Cell biology, Cystic fibrosis, Cystic fibrosis transmembrane conductance regulator, Mutation and Endoplasmic reticulum.
Her Chloride channel study, which is part of a larger body of work in Cell biology, is frequently linked to Calcineurin, bridging the gap between disciplines.
Her work carried out in the field of Cystic fibrosis brings together such families of science as Basal and Genotype.
By researching both Cystic fibrosis transmembrane conductance regulator and Context, Margarida D. Amaral produces research that crosses academic boundaries.
Her research integrates issues of Messenger RNA and Function in her study of Mutation.
The Endoplasmic reticulum study combines topics in areas such as ER retention and Interactome.
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