World's Best Scientists 2026 revealed!
Eric J. Sorscher

Eric J. Sorscher

D-Index & Metrics

Molecular Biology

D-Index
67
Citations
13626
World Ranking
1585
National Ranking
800

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Eric J. Sorscher is affiliated with Emory University in the United States and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work spans several subfields, including pulmonary and respiratory medicine, molecular biology, genetics, epidemiology, and infectious diseases.

The scientist's research focuses on numerous topics, among which cystic fibrosis research advances is prominent, alongside neonatal respiratory health research, tracheal and airway disorders, respiratory viral infections research, RNA and protein synthesis mechanisms, virus-based gene therapy research, and advanced biosensing and bioanalysis techniques.

Frequent coauthors collaborating with Eric J. Sorscher include Jeong S. Hong, András Rab, C. Barillà, Brian R. Davis, and Candela Manfredi, reflecting a broad network of scientific partnerships.

Eric J. Sorscher has published multiple papers in several high-impact venues, with the most frequent outlets being the Journal of Cystic Fibrosis, bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, Nature Communications, and PLoS ONE.

  • Type I and Type III Interferons Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures (2020) - Journal of Virology
  • A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion (2021) - Nature Communications
  • Engineered tRNAs suppress nonsense mutations in cells and in vivo (2023) - Nature
  • Highly Efficient Gene Editing of Cystic Fibrosis Patient-Derived Airway Basal Cells Results in Functional CFTR Correction (2020) - Molecular Therapy
  • High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo (2023) - Journal of Controlled Release

The scientist has been recognized as a member of the Association of American Physicians. Their research output includes 78 publications in medicine and 41 in biochemistry, genetics, and molecular biology, with a notable emphasis on pulmonary and respiratory medicine represented by 60 publications.

Best Publications

  • Characterization and Dynamics of Aggresome Formation by a Cytosolic Gfp-Chimera✪

    Rafael García-Mata;Zsuzsa Bebök;Eric J. Sorscher;Elizabeth S. Sztul

  • From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations.

    Gudio Veit;Radu G. Avramescu;Annette N. Chiang;Scott A. Houck

  • Regulation of plasma membrane recycling by CFTR

    Neil A. Bradbury;Tamas Jilling;Gabor Berta;Eric J. Sorscher

  • SUPPRESSION OF A CFTR PREMATURE STOP MUTATION IN A BRONCHIAL EPITHELIAL CELL LINE

    David M. Bedwell;Anisa Kaenjak;Dale J. Benos;Zsuzsa Bebok

  • Type I and Type III Interferons Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures.

    Abigail Vanderheiden;Philipp Ralfs;Philipp Ralfs;Tatiana Chirkova;Amit A. Upadhyay;Amit A. Upadhyay

  • Evidence that Systemic Gentamicin Suppresses Premature Stop Mutations in Patients with Cystic Fibrosis

    J. P. Clancy;Zsuzsa Bebök;Fadel Ruiz;Chris King

  • Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis

    Darren M Hutt;David Herman;Ana P C Rodrigues;Sabrina Noel

  • A clinical inflammatory syndrome attributable to aerosolized lipid-DNA administration in cystic fibrosis.

    F. E. Ruiz;J. P. Clancy;M. A. Perricone;Z. Bebok

  • A macromolecular complex of β2 adrenergic receptor, CFTR, and ezrin/radixin/moesin-binding phosphoprotein 50 is regulated by PKA

    Anjaparavanda P. Naren;Bryan Cobb;Chunying Li;Koushik Roy

  • “CFTR Modulator Theratyping: Current Status, Gaps and Future Directions”

    John Paul Clancy;Calvin U. Cotton;Scott H. Donaldson;George M. Solomon

  • Expression and polarized targeting of a rab3 isoform in epithelial cells.

    E Weber;G Berta;A Tousson;P St John

  • Tumor cell bystander killing in colonic carcinoma utilizing the Escherichia coli DeoD gene to generate toxic purines.

    Sorscher Ej;Peng S;Bebok Z;Allan Pw

  • Failure of cAMP agonists to activate rescued ΔF508 CFTR in CFBE41o– airway epithelial monolayers

    Zsuzsa Bebok;James F. Collawn;John Wakefield;William Parker

  • Aminoglycoside suppression of a premature stop mutation in a Cftr-/- mouse carrying a human CFTR-G542X transgene.

    Ming Du;Julie R. Jones;Jessica Lanier;Kim M. Keeling

  • A pharmacologic approach to acquired cystic fibrosis transmembrane conductance regulator dysfunction in smoking related lung disease.

    Peter A. Sloane;Suresh Shastry;Andrew Wilhelm;Clifford Courville

  • Targeted correction and restored function of the CFTR gene in cystic fibrosis induced pluripotent stem cells.

    Ana M. Crane;Philipp Kramer;Jacquelin H. Bui;Wook Joon Chung

  • Cigarette smoke condensate inhibits transepithelial chloride transport and ciliary beat frequency.

    Noam A. Cohen;Shaoyan Zhang;Dawn B. Sharp;Edwin Tamashiro

  • CFTR involvement in chloride, bicarbonate, and liquid secretion by airway submucosal glands.

    Stephen T. Ballard;Laura Trout;Zsuzsa Bebök;E. J. Sorscher

  • Method for quantitative study of airway functional microanatomy using micro-optical coherence tomography.

    Linbo Liu;Kengyeh K. Chu;Grace H. Houser;Bradford J. Diephuis;Bradford J. Diephuis

  • The Mechanism Underlying Cystic Fibrosis Transmembrane Conductance Regulator Transport from the Endoplasmic Reticulum to the Proteasome Includes Sec61β and a Cytosolic, Deglycosylated Intermediary

    Zsuzsa Bebök;Christopher Mazzochi;Scott A. King;Jeong S. Hong

Frequent Co-Authors

Steven M. Rowe
Steven M. Rowe University of Alabama at Birmingham
John P. Clancy
John P. Clancy Cystic Fibrosis Foundation
Dale J. Benos
Dale J. Benos University of Alabama at Birmingham
James F. Collawn
James F. Collawn University of Alabama at Birmingham
Sadis Matalon
Sadis Matalon University of Alabama at Birmingham
Gergely L. Lukacs
Gergely L. Lukacs McGill University
David M. Bedwell
David M. Bedwell University of Alabama at Birmingham
Catherine M. Fuller
Catherine M. Fuller University of Alabama at Birmingham
Raymond A. Frizzell
Raymond A. Frizzell University of Pittsburgh
Garry R. Cutting
Garry R. Cutting Johns Hopkins University School of Medicine

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