World's Best Scientists 2026 revealed!
William E. Balch

William E. Balch

D-Index & Metrics

Biology and Biochemistry

D-Index
112
Citations
48549
World Ranking
892
National Ranking
557

William E. Balch publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where William E. Balch sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 302 publications — 79th percentile

79% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

William E. Balch D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where William E. Balch sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 112 D-Index — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

William E. Balch is affiliated with Scripps Health in the United States and has an extensive research portfolio primarily in the field of Biochemistry, Genetics, and Molecular Biology. Their work spans 39 publications within this main field, with significant contributions specifically in subfields such as Molecular Biology, Genetics, Physiology, Pulmonary and Respiratory Medicine, and Cell Biology.

Balch's research focuses on several main topics including:

  • Protein Structure and Dynamics
  • Bacterial Genetics and Biotechnology
  • Cystic Fibrosis Research Advances
  • Heat Shock Proteins Research
  • Machine Learning in Bioinformatics
  • Single-cell and Spatial Transcriptomics
  • Endoplasmic Reticulum Stress and Disease

Their recent published papers showcase a range of study areas and publication venues. Notable publications include:

  • "The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging," 2021, Journal of Clinical Investigation
  • "Aging is associated with a systemic length-associated transcriptome imbalance," 2022, Nature Aging
  • "Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding," 2020, Diabetes
  • "Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone," 2020, Cell Chemical Biology
  • "Correction of Niemann-Pick type C1 trafficking and activity with the histone deacetylase inhibitor valproic acid," 2020, Journal of Biological Chemistry

Balch has collaborated frequently with several co-authors, including:

  • Chao Wang (13 co-authored publications)
  • Frédéric Anglès (7 co-authored publications)
  • Shuhong Sun (6 co-authored publications)
  • Pei Zhao (4 co-authored publications)
  • Jeffery W. Kelly (4 co-authored publications)

Frequent publication venues for Balch's work include:

  • bioRxiv (Cold Spring Harbor Laboratory) - 3 publications
  • UNC Libraries - 3 publications
  • Diabetes - 2 publications
  • Cell Chemical Biology - 2 publications
  • Communications Biology - 2 publications

Best Publications

  • Methanogens: reevaluation of a unique biological group.

    W E Balch;G E Fox;L J Magrum;C R Woese

  • Adapting proteostasis for disease intervention.

    William E. Balch;Richard I. Morimoto;Andrew Dillin;Jeffery W. Kelly

  • The Phylogeny of Prokaryotes

    GE Fox;E Stackebrandt;RB Hespell;J Gibson

  • Biological and Chemical Approaches to Diseases of Proteostasis Deficiency

    Evan T. Powers;Richard I. Morimoto;Andrew Dillin;Jeffery W. Kelly

  • Functional amyloid--from bacteria to humans.

    Douglas M. Fowler;Atanas V. Koulov;William E. Balch;Jeffery W. Kelly

  • Functional amyloid formation within mammalian tissue

    Douglas M Fowler;Atanas V Koulov;Christelle Alory-Jost;Michael S Marks

  • Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span.

    Alexander V. Misharin;Luisa Morales-Nebreda;Paul A. Reyfman;Carla M. Cuda

  • Reconstitution of the transport of protein between successive compartments of the golgi measured by the coupled incorporation of N-acetylglucosamine

    William E. Balch;William G. Dunphy;William A. Braell;James E. Rothman

  • A Di-Acidic Signal Required for Selective Export from the Endoplasmic Reticulum

    Noriyuki Nishimura;William E. Balch

  • Hsp90 Cochaperone Aha1 Downregulation Rescues Misfolding of CFTR in Cystic Fibrosis

    Xiaodong Wang;John Venable;Paul LaPointe;Darren M. Hutt

  • Rab1 Recruitment of p115 into a cis-SNARE Complex: Programming Budding COPII Vesicles for Fusion

    Bernard B. Allan;Bryan D. Moyer;William E. Balch

  • GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex.

    Ellen J. Tisdale;Jeffrey R. Bourne;Roya Khosravi-Far;Channing J. Der

  • Chemical chaperones increase the cellular activity of N370S β-glucosidase: A therapeutic strategy for Gaucher disease

    Anu R. Sawkar;Wei-Chieh Cheng;Ernest Beutler;Chi-Huey Wong

  • The organization of endoplasmic reticulum export complexes.

    S I Bannykh;T Rowe;W E Balch

  • Dominant inhibitory mutants of ARF1 block endoplasmic reticulum to Golgi transport and trigger disassembly of the Golgi apparatus.

    C. Dascher;W.E. Balch

  • Acetobacterium, a New Genus of Hydrogen-Oxidizing, Carbon Dioxide-Reducing, Anaerobic Bacteria

    William E. Balch;S. Schoberth;Ralph S. Tanner;R. S. Wolfe

  • GTPases: Multifunctional Molecular Switches Regulating Vesicular Traffic

    Claude Nuoffer;William E. Balch

  • From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations.

    Gudio Veit;Radu G. Avramescu;Annette N. Chiang;Scott A. Houck

  • The Biological and Chemical Basis for Tissue-Selective Amyloid Disease

    Yoshiki Sekijima;R. Luke Wiseman;Jeanne Matteson;Per Hammarström

  • Classification of methanogenic bacteria by 16S ribosomal RNA characterization.

    George E. Fox;Linda J. Magrum;William E. Balch;Ralph S. Wolfe

Frequent Co-Authors

Jeffery W. Kelly
Jeffery W. Kelly Scripps Research Institute
Richard I. Morimoto
Richard I. Morimoto Northwestern University
John R. Yates
John R. Yates Scripps Research Institute
Jacob I. Sznajder
Jacob I. Sznajder Northwestern University
Navdeep S. Chandel
Navdeep S. Chandel Northwestern University
G. R. Scott Budinger
G. R. Scott Budinger Northwestern University
Ian A. Wilson
Ian A. Wilson Scripps Research Institute
Karen M. Ridge
Karen M. Ridge Northwestern University
Channing J. Der
Channing J. Der University of North Carolina at Chapel Hill
Ralph S. Wolfe
Ralph S. Wolfe University of Illinois at Urbana-Champaign

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