What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Cell biology, Endoplasmic reticulum, Golgi apparatus, Biochemistry and Secretory pathway.
His study in Cell biology is interdisciplinary in nature, drawing from both Vesicle and Vesicular transport protein.
William E. Balch has researched Endoplasmic reticulum in several fields, including GTP-binding protein regulators, Vesicular stomatitis virus, Membrane transport and Transmembrane protein.
His Golgi apparatus study combines topics from a wide range of disciplines, such as Transport protein, GTPase, G protein and Cytosol.
His work on Chaperone and Protein folding as part of general Biochemistry study is frequently connected to Methanobacterium thermoautotrophicum, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His Secretory pathway study incorporates themes from Cathepsin D, LY294002, Mutant, Wortmannin and Vacuole.
His most cited work include:
- Methanogens: reevaluation of a unique biological group. (2233 citations)
- Adapting proteostasis for disease intervention. (1663 citations)
- The phylogeny of prokaryotes (1197 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Cell biology, Endoplasmic reticulum, Golgi apparatus, Biochemistry and Secretory pathway.
His research in Cell biology focuses on subjects like Vesicle, which are connected to Budding.
The study incorporates disciplines such as Transport protein, Vesicular stomatitis virus, Vesicular transport protein and Protein folding in addition to Endoplasmic reticulum.
His Golgi apparatus research is multidisciplinary, incorporating elements of Cell-free system, G protein and Cytosol.
William E. Balch works mostly in the field of Biochemistry, limiting it down to concerns involving Amyloid disease and, occasionally, Amyloidosis.
William E. Balch combines subjects such as Cellular compartment and Secretory protein with his study of Secretory pathway.
He most often published in these fields:
- Cell biology (69.44%)
- Endoplasmic reticulum (42.36%)
- Golgi apparatus (28.82%)
What were the highlights of his more recent work (between 2012-2021)?
- Cell biology (69.44%)
- Proteostasis (13.89%)
- Computational biology (6.60%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Cell biology, Proteostasis, Computational biology, Protein folding and NPC1.
His study in Cell biology focuses on Chaperone in particular.
The various areas that William E. Balch examines in his Proteostasis study include Proteome, Bioinformatics, Alpha 1-antitrypsin deficiency, Function and Protein structure.
His Computational biology research is multidisciplinary, incorporating perspectives in Precision medicine, Epigenetics, Genetic variation and Disease.
He has included themes like Signal transduction and Heat shock in his Protein folding study.
His Endosome research also works with subjects such as
- Mutation, which have a strong connection to Endoplasmic reticulum,
- Vorinostat which connect with Cholesterol storage, Mutant and Panobinostat.
Between 2012 and 2021, his most popular works were:
- Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span. (360 citations)
- From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations. (233 citations)
- Diversity in the origins of proteostasis networks--a driver for protein function in evolution. (168 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in Cell biology, Lung, Proteostasis, NPC1 and Cystic fibrosis transmembrane conductance regulator.
His biological study spans a wide range of topics, including Proteome and Proteomics.
His Lung research includes elements of Transcriptome, Immunology and Pathology.
His Proteostasis research focuses on subjects like Computational biology, which are linked to Phenotype, Natural selection, Whole genome sequencing, Genomics and Phenomics.
His NPC1 study integrates concerns from other disciplines, such as Vorinostat, Maladaptation and Niemann–Pick disease, type C.
His Niemann–Pick disease, type C study is concerned with the larger field of Biochemistry.
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