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D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
12815
World Ranking
10866
National Ranking
4711

Overview

Karen M. Ridge is affiliated with Northwestern University in the United States. Their research encompasses multiple areas within medicine and biochemistry, genetics, and molecular biology, with a particular focus on immunology, molecular biology, cell biology, pulmonary and respiratory medicine, and epidemiology.

The scientist's publication record features numerous papers across prominent venues. Recent papers include:

  • Roles of vimentin in health and disease, 2022, Genes & Development
  • Ineffectual Type 2-to-Type 1 Alveolar Epithelial Cell Differentiation in Idiopathic Pulmonary Fibrosis: Persistence of the KRT8hi Transitional State, 2020, American Journal of Respiratory and Critical Care Medicine
  • The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging, 2021, Journal of Clinical Investigation
  • The cGAS-STING pathway: The role of self-DNA sensing in inflammatory lung disease, 2020, The FASEB Journal
  • Aging is associated with a systemic length-associated transcriptome imbalance, 2022, Nature Aging

Frequent co-authors in their work include:

  • G. R. Scott Budinger
  • Hiam Abdala-Valencia
  • Alexander V. Misharin
  • Navdeep S. Chandel
  • Benjamin D. Singer

The scientist's publications are commonly found in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Respiratory and Critical Care Medicine
  • The FASEB Journal
  • Nature Immunology
  • Journal of Clinical Investigation

The research topics they cover include:

  • Skin and Cellular Biology Research
  • Immune cells in cancer
  • Immune Response and Inflammation
  • COVID-19 Clinical Research Studies
  • Influenza Virus Research Studies
  • Immune Cell Function and Interaction
  • Cellular Mechanics and Interactions

This body of work reflects a comprehensive engagement with cellular biology and immune function, with applications in disease contexts such as pulmonary fibrosis, inflammatory lung disease, and aging processes. The multidisciplinary approach is evident through the integration of molecular biology and clinical respiratory medicine.

Best Publications

  • Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis.

    Paul Andrew Reyfman;James McCauley Walter;Nikita Joshi;Kishore R. Anekalla

  • Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span.

    Alexander V. Misharin;Luisa Morales-Nebreda;Paul A. Reyfman;Carla M. Cuda

  • Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia.

    Rogan A Grant;Luisa Morales-Nebreda;Nikolay S Markov;Suchitra Swaminathan

  • Influenza virus-induced lung injury: pathogenesis and implications for treatment

    Susanne Herold;Christin Becker;Karen M. Ridge;G.R. Scott Budinger

  • The Role of Vimentin Intermediate Filaments in the Progression of Lung Cancer

    Martha E. Kidd;Dale K. Shumaker;Karen M. Ridge

  • Hypoxia-induced endocytosis of Na,K-ATPase in alveolar epithelial cells is mediated by mitochondrial reactive oxygen species and PKC-ζ

    Laura A. Dada;Navdeep S. Chandel;Karen M. Ridge;Carlos Pedemonte

  • Vimentin regulates activation of the NLRP3 inflammasome

    Gimena dos Santos;Micah R. Rogel;Margaret A. Baker;James R. Troken

  • Isoproterenol increases Na+-K+-ATPase activity by membrane insertion of α-subunits in lung alveolar cells

    Alejandro M. Bertorello;Karen M. Ridge;Alexander V. Chibalin;Adrian I. Katz

  • The inflammasome in lung diseases.

    Gimena dos Santos;Mikhail A. Kutuzov;Karen M. Ridge;Karen M. Ridge

  • Augmentation of lung liquid clearance via adenovirus-mediated transfer of a Na,K-ATPase beta1 subunit gene.

    F Saldias;K Ridge;V Dumasius

  • Flow Cytometry Reveals Similarities Between Lung Macrophages in Humans and Mice

    Ankit Bharat;Sangeeta M Bhorade;Luisa Morales-Nebreda;Alexandra C McQuattie-Pimentel

  • Alveolar Type 1 Cells Express the α2 Na,K-ATPase, Which Contributes to Lung Liquid Clearance

    K.M. Ridge;W.G. Olivera;F. Saldias;Z. Azzam

  • Keratin 8 Phosphorylation by Protein Kinase C δ Regulates Shear Stress-mediated Disassembly of Keratin Intermediate Filaments in Alveolar Epithelial Cells

    Karen M. Ridge;Karen M. Ridge;Laura Linz;Frederick W. Flitney;Edward R. Kuczmarski

  • Mitochondrial Complex III-generated Oxidants Activate ASK1 and JNK to Induce Alveolar Epithelial Cell Death following Exposure to Particulate Matter Air Pollution

    Saul Soberanes;Daniela Urich;Christina M. Baker;Zach O. Burgess

  • Active sodium transport and alveolar epithelial Na-K-ATPase increase during subacute hyperoxia in rats

    W. Olivera;K. Ridge;L. D. H. Wood;J. I. Sznajder

  • Lung Liquid Clearance and Na/K-ATPase during Acute Hyperoxia and Recovery in Rats

    W G Olivera;K M Ridge;J I Sznajder

  • Ventilator-associated Lung Injury Decreases Lung Ability to Clear Edema in Rats

    E. Lecuona;F. Saldías;A. Comellas;K. Ridge

  • Vimentin is sufficient and required for wound repair and remodeling in alveolar epithelial cells

    Micah R. Rogel;Pritin N. Soni;James R. Troken;Albert Sitikov

  • Ineffectual Type 2-to-Type 1 Alveolar Epithelial Cell Differentiation in Idiopathic Pulmonary Fibrosis: Persistence of the KRT8hi Transitional State.

    Peng Jiang;Rafael Gil de Rubio;Steven M. Hrycaj;Stephen J. Gurczynski

  • Evidence for the role of alveolar epithelial gp60 in active transalveolar albumin transport in the rat lung.

    Theresa A. John;Stephen M. Vogel;Richard D. Minshall;Karen Ridge

Frequent Co-Authors

Jacob I. Sznajder
Jacob I. Sznajder Northwestern University
G. R. Scott Budinger
G. R. Scott Budinger Northwestern University
Navdeep S. Chandel
Navdeep S. Chandel Northwestern University
Harris Perlman
Harris Perlman Northwestern University
David W. Kamp
David W. Kamp Northwestern University
Robert D. Goldman
Robert D. Goldman Northwestern University
William E. Balch
William E. Balch Scripps Health
Richard I. Morimoto
Richard I. Morimoto Northwestern University
Cara J. Gottardi
Cara J. Gottardi Northwestern University
Annie Pardo
Annie Pardo National Autonomous University of Mexico

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