2019 - Member of the National Academy of Sciences
2019 - Fellow, National Academy of Inventors
His primary scientific interests are in Virology, Virus, Influenza A virus, Interferon and Viral replication. His work deals with themes such as H5N1 genetic structure, Immunology and Microbiology, which intersect with Virology. His Virus research focuses on Orthomyxoviridae in particular.
Adolfo García-Sastre interconnects Neuraminidase, Influenza A virus subtype H5N1, Gene, Virulence and Viral transformation in the investigation of issues within Influenza A virus. His Interferon research is multidisciplinary, incorporating perspectives in Innate immune system, Interferon regulatory factors, Signal transduction and Dengue virus. His Viral replication study incorporates themes from RNA, Genome and Cell biology.
Adolfo García-Sastre spends much of his time researching Virology, Virus, Influenza A virus, Interferon and Viral replication. His work in Virology addresses issues such as Immunology, which are connected to fields such as Cytotoxic T cell. He has included themes like Antibody, H5N1 genetic structure and Vaccination in his Virus study.
His Influenza A virus study combines topics in areas such as Molecular biology, Pandemic, Recombinant virus and Virulence. His studies in Interferon integrate themes in fields like RIG-I, Innate immune system, Signal transduction and Gene. Adolfo García-Sastre usually deals with Viral replication and limits it to topics linked to RNA and Cell biology.
Virology, Virus, Influenza A virus, Antibody and Viral replication are his primary areas of study. He combines subjects such as Innate immune system and Immune system with his study of Virology. His Virus research is within the category of Immunology.
The Influenza A virus study combines topics in areas such as Influenza A virus subtype H5N1 and Tropism. Adolfo García-Sastre works mostly in the field of Antibody, limiting it down to topics relating to Severe acute respiratory syndrome coronavirus 2 and, in certain cases, Pandemic, Drug repositioning and Drug. In his research, Protease is intimately related to Hepatitis C virus, which falls under the overarching field of Viral replication.
His primary areas of study are Virology, Virus, Antibody, Influenza A virus and Viral replication. His Virology study frequently draws connections between related disciplines such as Coronavirus. His Virus research incorporates elements of Transmission, Interferon, Asymptomatic and Interleukin 8.
His Interferon research incorporates themes from Innate immune system and IRF3. His Influenza A virus study integrates concerns from other disciplines, such as Tropism and Sialic acid. His Viral replication research is multidisciplinary, relying on both Blocking antibody, Signal transduction, Flavivirus, Dengue virus and Drug.
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Characterization of the reconstructed 1918 Spanish influenza pandemic virus
Terrence M. Tumpey;Christopher F. Basler;Patricia V. Aguilar;Hui Zeng.
Science (2005)
Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes
Daigo Hashimoto;Andrew Chow;Andrew Chow;Clara Noizat;Clara Noizat;Pearline Teo.
Immunity (2013)
Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems
Adolfo García-Sastre;Andrej Egorov;Demetrius Matassov;Sabine Brandt.
Virology (1998)
Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity
Yueh Ming Loo;Jamie Fornek;Nanette Crochet;Gagan Bajwa.
Journal of Virology (2008)
Type 1 Interferons and the Virus-Host Relationship: A Lesson in Détente
Adolfo García-Sastre;Christine A. Biron.
Science (2006)
Rescue of Influenza A Virus from Recombinant DNA
Ervin Fodor;Louise Devenish;Othmar G. Engelhardt;Peter Palese.
Journal of Virology (2007)
Programming the magnitude and persistence of antibody responses with innate immunity.
Sudhir Pai Kasturi;Ioanna Skountzou;Randy A. Albrecht;Dimitrios Koutsonanos.
Nature (2011)
Human host factors required for influenza virus replication
Renate König;Silke Stertz;Yingyao Zhou;Atsushi Inoue.
Nature (2010)
Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I
Michaela Ulrike Gack;Randy Allen Albrecht;Tomohiko Urano;Tomohiko Urano;Kyung-Soo Inn;Kyung-Soo Inn.
Cell Host & Microbe (2009)
Activation of Interferon Regulatory Factor 3 Is Inhibited by the Influenza A Virus NS1 Protein
Julie Talon;Curt M. Horvath;Rosalind Polley;Christopher F. Basler.
Journal of Virology (2000)
Vaccine
(Impact Factor: 4.169)
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