World's Best Scientists 2026 revealed!
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Microbiology
USA
2026

D-Index & Metrics

Best Scientists

D-Index
166
Citations
107769
World Ranking
1006
National Ranking
595

Microbiology

D-Index
169
Citations
104179
World Ranking
13
National Ranking
7

Research.com Recognitions

  • 2026 - Research.com Microbiology in United States Leader Award
  • 2025 - Research.com Microbiology in United States Leader Award
  • 2019 - Member of the National Academy of Sciences
  • 2019 - Fellow, National Academy of Inventors

Overview

Adolfo García-Sastre is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research primarily centers on the fields of medicine, with significant contributions in infectious diseases, epidemiology, immunology, molecular biology, and animal science and zoology.

The scientist's work extensively covers topics such as SARS-CoV-2 and COVID-19 research, influenza virus investigations, COVID-19 clinical studies, respiratory viral infections, interferon and immune responses, animal virus infections, and viral gastroenteritis research and epidemiology.

Recent publications include the following papers:

  • A serological assay to detect SARS-CoV-2 seroconversion in humans, 2020, Nature Medicine
  • The Global Phosphorylation Landscape of SARS-CoV-2 Infection, 2020, Cell
  • Animal models for COVID-19, 2020, Nature
  • Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing, 2020, Nature
  • SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters, 2022, Nature

The scientist frequently collaborates with colleagues in the field, including Michael Schotsaert, Florian Krammer, Lisa Miorin, Kris M. White, and Raveen Rathnasinghe. Their research has been published in a range of venues, notably bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, The Journal of Immunology, Emerging Microbes & Infections, and Nature.

Adolfo García-Sastre's contributions have been recognized through memberships and fellowships, including being a member of the National Academy of Sciences and a fellow of the National Academy of Inventors, both awarded in 2019.

Best Publications

  • A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

    David E. Gordon;Gwendolyn M. Jang;Mehdi Bouhaddou;Jiewei Xu

  • Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

    Daigo Hashimoto;Andrew Chow;Andrew Chow;Clara Noizat;Clara Noizat;Pearline Teo

  • A serological assay to detect SARS-CoV-2 seroconversion in humans.

    Fatima Amanat;Daniel Stadlbauer;Shirin Strohmeier;Shirin Strohmeier;Thi H. O. Nguyen

  • Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

    Qian Zhang;Paul Bastard;Paul Bastard;Zhiyong Liu;Jérémie Le Pen

  • Characterization of the reconstructed 1918 Spanish influenza pandemic virus

    Terrence M. Tumpey;Christopher F. Basler;Patricia V. Aguilar;Hui Zeng

  • Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

    Adolfo García-Sastre;Andrej Egorov;Demetrius Matassov;Sabine Brandt

  • Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity

    Yueh Ming Loo;Jamie Fornek;Nanette Crochet;Gagan Bajwa

  • Type 1 Interferons and the Virus-Host Relationship: A Lesson in Détente

    Adolfo García-Sastre;Christine A. Biron

  • Programming the magnitude and persistence of antibody responses with innate immunity.

    Sudhir Pai Kasturi;Ioanna Skountzou;Randy A. Albrecht;Dimitrios Koutsonanos

  • The Global Phosphorylation Landscape of SARS-CoV-2 Infection.

    Mehdi Bouhaddou;Danish Memon;Bjoern Meyer;Kris M. White

  • Rescue of Influenza A Virus from Recombinant DNA

    Ervin Fodor;Louise Devenish;Othmar G. Engelhardt;Peter Palese

  • Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I

    Michaela Ulrike Gack;Randy Allen Albrecht;Tomohiko Urano;Tomohiko Urano;Kyung-Soo Inn;Kyung-Soo Inn

  • Human host factors required for influenza virus replication

    Renate König;Silke Stertz;Yingyao Zhou;Atsushi Inoue

  • Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

    John W. Schoggins;Donna A. MacDuff;Naoko Imanaka;Maria D. Gainey

  • Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding

    Shashank Tripathi;Marie O. Pohl;Yingyao Zhou;Ariel Rodriguez-Frandsen

  • Inhibition of interferon signaling by dengue virus

    Jorge L. Muñoz-Jordán;Gilma G. Sánchez-Burgos;Maudry Laurent-Rolle;Adolfo García-Sastre

  • Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling

    Alesha Grant;Sanket S. Ponia;Shashank Tripathi;Vinod Balasubramaniam

  • Influenza A viruses: new research developments

    Rafael A. Medina;Adolfo García-Sastre

  • Animal models for COVID-19.

    César Muñoz-Fontela;William E. Dowling;Simon G.P. Funnell;Pierre S. Gsell

  • Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing.

    Laura Riva;Shuofeng Yuan;Xin Yin;Laura Martin-Sancho

  • Activation of Interferon Regulatory Factor 3 Is Inhibited by the Influenza A Virus NS1 Protein

    Julie Talon;Curt M. Horvath;Rosalind Polley;Christopher F. Basler

  • Influenza A Virus NS1 Protein Prevents Activation of NF-κB and Induction of Alpha/Beta Interferon

    Xiuyan Wang;Ming Li;Hongyong Zheng;Thomas Muster

Frequent Co-Authors

Peter Palese
Peter Palese Icahn School of Medicine at Mount Sinai
Randy A. Albrecht
Randy A. Albrecht Icahn School of Medicine at Mount Sinai
Florian Krammer
Florian Krammer Icahn School of Medicine at Mount Sinai
Luis Martínez-Sobrido
Luis Martínez-Sobrido Texas Biomedical Research Institute
Christopher F. Basler
Christopher F. Basler University of Georgia
Ana Fernandez-Sesma
Ana Fernandez-Sesma Icahn School of Medicine at Mount Sinai
Terrence M. Tumpey
Terrence M. Tumpey Centers for Disease Control and Prevention
Martin Schwemmle
Martin Schwemmle University of Freiburg
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco
Georg Kochs
Georg Kochs University of Freiburg

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