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Immunology

D-Index
87
Citations
22880
World Ranking
1223
National Ranking
78

Overview

Stephan Ludwig is affiliated with the University of Münster in Germany and has contributed extensively to the field of medicine, with a particular focus on infectious diseases. Their research output spans multiple subfields, including epidemiology, immunology, molecular biology, and cardiology and cardiovascular medicine.

The research topics that Ludwig has notably worked on include:

  • SARS-CoV-2 and COVID-19 Research
  • Influenza Virus Research Studies
  • Interferon and immune responses
  • COVID-19 Clinical Research Studies
  • Respiratory viral infections research
  • Virus-based gene therapy research
  • Long-Term Effects of COVID-19

Ludwig's publication record includes a number of recent papers focused on viral infections and therapeutic strategies. Significant papers authored or coauthored by Ludwig include:

  • "Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity" (2021) published in EBioMedicine
  • "Coronaviruses and SARS-CoV-2: A Brief Overview" (2020) published in Anesthesia & Analgesia
  • "Targeting the endolysosomal host-SARS-CoV-2 interface by clinically licensed functional inhibitors of acid sphingomyelinase (FIASMA) including the antidepressant fluoxetine" (2020) published in Emerging Microbes & Infections
  • "A Pandemic in Times of Global Tourism: Superspreading and Exportation of COVID-19 Cases from a Ski Area in Austria" (2020) published in Journal of Clinical Microbiology
  • "Drug synergy of combinatory treatment with remdesivir and the repurposed drugs fluoxetine and itraconazole effectively impairs SARS-CoV-2 infection in vitro" (2021) published in British Journal of Pharmacology

Their frequent collaborators include Linda Brunotte, Eike R. Hrincius, André Schreiber, Yvonne Boergeling, and Alexander Mellmann, indicating a collaborative research environment.

Ludwig's work is regularly published in several venues, reflecting diverse dissemination of their research findings. Major publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Emerging Microbes & Infections
  • Antiviral Research
  • SSRN Electronic Journal
  • Nature Communications

Their research contributions within medicine cover 179 publications, with notable volume in infectious diseases (77 publications), epidemiology (47), immunology (41), molecular biology (24), and cardiology and cardiovascular medicine (11).

Best Publications

  • Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

    Thomas Vogl;Klaus Tenbrock;Stephan Ludwig;Nadja Leukert

  • Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade

    Stephan Pleschka;Thorsten Wolff;Christina Ehrhardt;Gerd Hobom

  • MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes.

    Thomas Vogl;Stephan Ludwig;Matthias Goebeler;Anke Strey

  • Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: results of a randomized and controlled phase IIb study

    Ulrich Bogdahn;Peter Hau;G. Stockhammer;N. K. Venkataramana

  • Caspase 3 activation is essential for efficient influenza virus propagation

    Walter J. Wurzer;Oliver Planz;Christina Ehrhardt;Martin Giner

  • Influenza A Virus NS1 Protein Activates the PI3K/Akt Pathway To Mediate Antiapoptotic Signaling Responses

    Christina Ehrhardt;Thorsten Wolff;Stephan Pleschka;Oliver Planz

  • IFN-α antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3

    Johannes G Bode;Stephan Ludwig;Christina Ehrhardt;Ute Albrecht

  • The Epidermal Growth Factor Receptor (EGFR) Promotes Uptake of Influenza A Viruses (IAV) into Host Cells

    Thorsten Eierhoff;Eike R. Hrincius;Ursula Rescher;Stephan Ludwig

  • Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity.

    Markus Hoffmann;Heike Hofmann-Winkler;Joan C. Smith;Nadine Krüger

  • Coronaviruses and SARS-CoV-2: A Brief Overview.

    Stephan Ludwig;Alexander Zarbock

  • Influenza A Virus Inhibits Type I IFN Signaling via NF-κB-Dependent Induction of SOCS-3 Expression

    Eva-K. Pauli;Mirco Schmolke;Thorsten Wolff;Dorothee Viemann

  • NF-κB-dependent Induction of Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) and Fas/FasL Is Crucial for Efficient Influenza Virus Propagation

    Walter J. Wurzer;Christina Ehrhardt;Stephan Pleschka;Friederike Berberich-Siebelt

  • Multiple signaling pathways regulate NF-κB–dependent transcription of the monocyte chemoattractant protein-1 gene in primary endothelial cells

    Matthias Goebeler;Reinhard Gillitzer;Karin Kilian;Kathrin Utzel

  • Bivalent role of the phosphatidylinositol-3-kinase (PI3K) during influenza virus infection and host cell defence.

    Christina Ehrhardt;Henju Marjuki;Thorsten Wolff;Bernd Nürnberg

  • Ringing the alarm bells: signalling and apoptosis in influenza virus infected cells

    Stephan Ludwig;Stephan Pleschka;Oliver Planz;Thorsten Wolff

  • Activation of NF-κB via the IκB Kinase Complex Is Both Essential and Sufficient for Proinflammatory Gene Expression in Primary Endothelial Cells

    Andrea Denk;Matthias Goebeler;Sybille Schmid;Ingolf Berberich

  • The Influenza A Virus NS1 Protein Inhibits Activation of Jun N-Terminal Kinase and AP-1 Transcription Factors

    Stephan Ludwig;Xiuyan Wang;Christina Ehrhardt;Hongyong Zheng

  • The MKK6/p38 Stress Kinase Cascade Is Critical for Tumor Necrosis Factor-α–Induced Expression of Monocyte-Chemoattractant Protein-1 in Endothelial Cells

    Matthias Goebeler;Karin Kilian;Reinhard Gillitzer;Manfred Kunz

  • Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF-kappa B-inhibiting activity

    Igor Mazur;Walter J. Wurzer;Christina Ehrhardt;Stephan Pleschka

  • Influenza virus-induced AP-1-dependent gene expression requires activation of the JNK signaling pathway.

    Stephan Ludwig;Christina Ehrhardt;Elisabeth R. Neumeier;Michael Kracht

  • A new player in a deadly game: influenza viruses and the PI3K/Akt signalling pathway.

    Christina Ehrhardt;Stephan Ludwig

  • Polyethylenimine, a cost-effective transfection reagent

    Christina Ehrhardt;Mirco Schmolke;Andreas Matzke;Alexander Knoblauch

  • MRP8 AND MRP14 CONTROL MICROTUBULE REORGANIZATION DURING TRANSENDOTHELIAL MIGRATION OF PHAGOCYTES. running title: MRP8/MRP14 complexes and migration of phagocytes

    Dirk Foell;Volker Gerke;Wolfgang Nacken;Sabine Werner

Frequent Co-Authors

Stephan Pleschka
Stephan Pleschka University of Giessen
Oliver Planz
Oliver Planz University of Tübingen
Thorsten Wolff
Thorsten Wolff Robert Koch Institute
Ulf R. Rapp
Ulf R. Rapp Max Planck Society
Johannes Roth
Johannes Roth University of Münster
Matthias Goebeler
Matthias Goebeler University of Würzburg
Christoph Scholtissek
Christoph Scholtissek University of Giessen
Werner Wegscheider
Werner Wegscheider Solid State Physics Laboratory
Ulrich S. Schubert
Ulrich S. Schubert Friedrich Schiller University Jena
Volker Gerke
Volker Gerke University of Münster

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