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Immunology

D-Index
118
Citations
44095
World Ranking
361
National Ranking
15

Medicine

D-Index
119
Citations
45636
World Ranking
3928
National Ranking
218

Overview

Johannes Roth is affiliated with the University of Münster in Germany. The scientist's research spans multiple fields, with a primary focus on Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Their work concentrates on several subfields, including Immunology, Molecular Biology, Pulmonary and Respiratory Medicine, Epidemiology, and Immunology and Allergy.

The main topics addressed in their publications include:

  • S100 Proteins and Annexins
  • Immune Response and Inflammation
  • Immune cells in cancer
  • Cell Adhesion Molecules Research
  • Inflammasome and immune disorders
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Autoimmune and Inflammatory Disorders Research

Johannes Roth's recent papers demonstrate a focus on inflammation, immune system development, and cellular mechanisms associated with disease. Selected publications include:

  • "Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils" (2020), published in Science Translational Medicine
  • "The Good and the Bad: Monocytes' and Macrophages' Diverse Functions in Inflammation" (2022), published in Cells
  • "S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants" (2020), published in Gastroenterology
  • "Pervasive head-to-tail insertions of DNA templates mask desired CRISPR-Cas9-mediated genome editing events" (2020), published in Science Advances
  • "Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells" (2022), published in JCI Insight

The research collaboration network of Johannes Roth includes frequent co-authorship with:

  • Thomas Vogl, with 48 joint publications
  • Arjen B. Blom, with 7 joint publications
  • Katarzyna Barczyk-Kahlert, with 6 joint publications
  • Dirk Holzinger, with 6 joint publications
  • Olesja Fehler, with 6 joint publications

Frequently visited publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory), with 8 publications
  • Osteoarthritis and Cartilage, with 6 publications
  • Frontiers in Immunology, with 4 publications
  • Nature Communications, with 4 publications
  • Journal of Allergy and Clinical Immunology, with 3 publications

Best Publications

  • Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

    Thomas Vogl;Klaus Tenbrock;Stephan Ludwig;Nadja Leukert

  • S100 proteins expressed in phagocytes: a novel group of damage-associated molecular pattern molecules

    Dirk Foell;Helmut Wittkowski;Thomas Vogl;Johannes Roth

  • Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

    Pingyan Cheng;Cesar A. Corzo;Noreen Luetteke;Bin Yu

  • The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer

    Jan M. Ehrchen;Cord Sunderkötter;Dirk Foell;Thomas Vogl

  • Myeloid-related protein (MRP) 8 and MRP14, calcium-binding proteins of the S100 family, are secreted by activated monocytes via a novel, tubulin-dependent pathway.

    Anke Rammes;Johannes Roth;Matthias Goebeler;Martin Klempt

  • Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel

    Marc Schmidt;Badrinarayanan Raghavan;Badrinarayanan Raghavan;Verena Müller;Verena Müller;Thomas Vogl

  • Alarmins: awaiting a clinical response.

    James K. Chan;Johannes Roth;Joost J. Oppenheim;Kevin J. Tracey

  • Staphylococcus aureus phenotype switching: an effective bacterial strategy to escape host immune response and establish a chronic infection

    Lorena Tuchscherr;Eva Medina;Muzaffar Hussain;Wolfgang Völker

  • Staphylococcus aureus Panton-Valentine Leukocidin Is a Very Potent Cytotoxic Factor for Human Neutrophils

    Bettina Löffler;Muzaffar Hussain;Matthias Grundmeier;Michaela Brück

  • Myeloid-related proteins 8 and 14 are specifically secreted during interaction of phagocytes and activated endothelium and are useful markers for monitoring disease activity in pauciarticular-onset juvenile rheumatoid arthritis

    Michael Frosch;Anke Strey;Thomas Vogl;Nico M. Wulffraat

  • Phagocyte-specific S100 proteins: a novel group of proinflammatory molecules

    Johannes Roth;Thomas Vogl;Clemens Sorg;Cord Sunderkötter;Cord Sunderkötter

  • Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype of human monocytes.

    Jan Ehrchen;Lars Steinmüller;Katarzyna Barczyk;Klaus Tenbrock

  • Mechanisms of disease: a 'DAMP' view of inflammatory arthritis.

    Dirk Foell;Helmut Wittkowski;Johannes Roth

  • Identification of Human S100A9 as a Novel Target for Treatment of Autoimmune Disease via Binding to Quinoline-3-Carboxamides

    Per Björk;Anders Björk;Thomas Vogl;Martin Stenström

  • Proinflammatory S100 proteins in arthritis and autoimmune disease.

    Dirk Foell;Johannes Roth

  • S100A9/S100A8: Myeloid representatives of the S100 protein family as prominent players in innate immunity.

    Wolfgang Nacken;Johannes Roth;Clemens Sorg;Claus Kerkhoff

  • MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes.

    Thomas Vogl;Stephan Ludwig;Matthias Goebeler;Anke Strey

  • S100A8/A9: From basic science to clinical application.

    Monika Pruenster;Thomas Vogl;Johannes Roth;Markus Sperandio

  • Loss of S100A9 (MRP14) results in reduced interleukin-8-induced CD11b surface expression, a polarized microfilament system, and diminished responsiveness to chemoattractants in vitro.

    Marie-Pierre Manitz;Basil Horst;Stephan Seeliger;Anke Strey

  • Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis.

    Arjen B. Blom;Peter L.E.M. van Lent;Astrid E.M. Holthuysen;Peter M. van der Kraan

  • Phagocyte-specific calcium-binding S100 proteins as clinical laboratory markers of inflammation.

    Dirk Foell;Michael Frosch;Clemens Sorg;Johannes Roth

  • Neutrophil derived human S100A12 (EN-RAGE) is strongly expressed during chronic active inflammatory bowel disease.

    D Foell;T Kucharzik;M Kraft;T Vogl

Frequent Co-Authors

Dirk Foell
Dirk Foell University of Münster
Thomas J. Vogl
Thomas J. Vogl Goethe University Frankfurt
Clemens Sorg
Clemens Sorg University of Münster
Matthias Goebeler
Matthias Goebeler University of Würzburg
Cord Sunderkötter
Cord Sunderkötter University of Münster
Stephan Ludwig
Stephan Ludwig University of Münster
Wim B. van den Berg
Wim B. van den Berg Radboud University
Lucy R. Wedderburn
Lucy R. Wedderburn University College London
Joachim L. Schultze
Joachim L. Schultze University of Bonn
Tom van der Poll
Tom van der Poll University of Amsterdam

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