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Molecular Biology

D-Index
59
Citations
10249
World Ranking
2038
National Ranking
1011

Research.com Recognitions

  • 2017 - Fellow of the Royal Society of Canada Academy of Science

Overview

Helen McNeill is affiliated with Washington University in St. Louis in the United States. Their research spans primarily the field of Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology and Cell Biology. Additional subfields include Surgery, Paleontology, and Physiology.

Their work frequently addresses topics such as Hippo pathway signaling and YAP/TAZ, Wnt/β-catenin signaling in development and cancer, Nuclear Structure and Function, Marine Invertebrate Physiology and Ecology, RNA Research and Splicing, Congenital Diaphragmatic Hernia Studies, and Renal and related cancers.

Recent publications authored or coauthored by Helen McNeill include:

  • Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development, 2020, Developmental Cell
  • Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow, 2020, Journal of Clinical Investigation
  • Ancestral roles of atypical cadherins in planar cell polarity, 2020, Proceedings of the National Academy of Sciences
  • The Hippo pathway regulates axis formation and morphogenesis in Hydra, 2022, Proceedings of the National Academy of Sciences
  • The NEMP family supports metazoan fertility and nuclear envelope stiffness, 2020, Science Advances

Helen McNeill has collaborated frequently with several researchers in their field. Notable coauthors include Didier Hodzic, Yonit Tsatskis, Nattapon Thanintorn, Yu Sun, and Maria Brooun.

Their research has been published in several venues, with multiple contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Biology Open
  • Developmental Cell
  • Journal of Clinical Investigation

Helen McNeill was awarded the Fellowship of the Royal Society of Canada in 2017 in recognition by the Academy of Science.

Best Publications

  • The Hippo Pathway Regulates Wnt/β-Catenin Signaling

    Xaralabos Varelas;Bryan W. Miller;Richelle Sopko;Richelle Sopko;Siyuan Song

  • Novel function of the cell adhesion molecule uvomorulin as an inducer of cell surface polarity

    Helen McNeill;Masayuki Ozawa;Rolf Kemler;W.James Nelson

  • Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease

    Sakura Saburi;Ian Hester;Evelyne Fischer;Marco Pontoglio

  • Fidelity in planar cell polarity signalling

    Dali Ma;Chung-hui Yang;Helen McNeill;Michael A. Simon

  • The Tumor-Suppressor Gene fat Controls Tissue Growth Upstream of Expanded in the Hippo Signaling Pathway

    Elizabeth Silva;Yonit Tsatskis;Laura Gardano;Nic Tapon

  • Planar polarity from flies to vertebrates

    Manolis Fanto;Helen McNeill

  • Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development

    Antoine Reginensi;Rizaldy P. Scott;Alex Gregorieff;Mazdak Bagherie-Lachidan;Mazdak Bagherie-Lachidan

  • Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development

    Silvia Cappello;Mary J Gray;Caroline Badouel;Caroline Badouel;Simona Lange

  • The FERM-Domain Protein Expanded Regulates Hippo Pathway Activity via Direct Interactions with the Transcriptional Activator Yorkie

    Caroline Badouel;Caroline Badouel;Laura Gardano;Laura Gardano;Nancy Amin;Nancy Amin;Ankush Garg;Ankush Garg

  • Drosophila insulin release is triggered by adipose Stunted ligand to brain Methuselah receptor

    Renald Delanoue;Eleonora Meschi;Neha Agrawal;Alessandra Mauri

  • mirror encodes a novel PBX-class homeoprotein that functions in the definition of the dorsal-ventral border in the Drosophila eye.

    H McNeill;C H Yang;M Brodsky;J Ungos

  • Spatial and temporal dissection of immediate and early events following cadherin-mediated epithelial cell adhesion.

    H McNeill;T A Ryan;S J Smith;W J Nelson

  • When pathways collide: collaboration and connivance among signalling proteins in development

    Helen McNeill;James R. Woodgett

  • Chemoattractant-stimulated polymorphonuclear leukocytes contain two populations of actin filaments that differ in their spatial distributions and relative stabilities.

    Lynne Cassimeris;Helen McNeill;Sally H. Zigmond

  • The tumor-suppressor and cell adhesion molecule Fat controls planar polarity via physical interactions with Atrophin, a transcriptional co-repressor

    Manolis Fanto;Lesley Clayton;Jamie Meredith;Kirsten Hardiman

  • The Drosophila trithorax group protein Kismet facilitates an early step in transcriptional elongation by RNA Polymerase II.

    Shrividhya Srinivasan;Jennifer A. Armstrong;Renate Deuring;Ina K. Dahlsveen

  • The SH2-containing tyrosine phosphatase corkscrew is required during signaling by sevenless, Ras1 and Raf

    John D. Allard;Henry C. Chang;Ronald Herbst;Helen McNeill

  • Temporal Control of Differentiation by the Insulin Receptor/Tor Pathway in Drosophila

    Joseph M. Bateman;Helen McNeill

  • Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity

    Sakura Saburi;Ian Hester;Lisa Goodrich;Helen McNeill;Helen McNeill

  • Herding Hippos: regulating growth in flies and man

    Caroline Badouel;Ankush Garg;Helen McNeill;Helen McNeill

Frequent Co-Authors

Jeffrey L. Wrana
Jeffrey L. Wrana Lunenfeld-Tanenbaum Research Institute
Georg Halder
Georg Halder KU Leuven
Martin Hirst
Martin Hirst University of British Columbia
Tony Pawson
Tony Pawson University of Toronto
Rod Bremner
Rod Bremner Lunenfeld-Tanenbaum Research Institute
Yu Sun
Yu Sun University of Toronto
Samuel Aparicio
Samuel Aparicio University of British Columbia
Friedhelm Hildebrandt
Friedhelm Hildebrandt Boston Children's Hospital
Brian Raught
Brian Raught Princess Margaret Cancer Centre
Benjamin M. Hogan
Benjamin M. Hogan University of Melbourne

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