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D-Index & Metrics

Molecular Biology

D-Index
80
Citations
34786
World Ranking
982
National Ranking
29

Overview

Brian Raught is affiliated with the Princess Margaret Cancer Centre in Canada. Their research spans a range of topics within biochemistry, genetics, molecular biology, and medicine, focusing extensively on molecular and cell biology, oncology, hematology, and genetics.

Raught's recent papers include the following:

  • A proximity-dependent biotinylation map of a human cell, 2021, Nature
  • MYC protein interactors in gene transcription and cancer, 2021, Nature Reviews. Cancer
  • A SARS-CoV-2 - host proximity interactome, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate, 2020, Cell
  • The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness, 2022, Nature Cell Biology

The scientist frequently publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Blood
  • Cancer Research
  • Preprints.org

Their most frequent co-authors include:

  • Jonathan St-Germain
  • Étienne Coyaud
  • Audrey Astori
  • Aaron D. Schimmer
  • C.H. Arrowsmith

Brian Raught's work covers key topics such as:

  • Ubiquitin and proteasome pathways
  • Epigenetics and DNA methylation
  • Biotin and related studies
  • Protein degradation and inhibitors
  • Genomics and chromatin dynamics
  • Acute myeloid leukemia research
  • RNA modifications and cancer

Within the fields of study, their publications are concentrated in:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields with significant representation include:

  • Molecular Biology
  • Cell Biology
  • Oncology
  • Hematology
  • Genetics

Best Publications

  • eIF4 Initiation Factors: Effectors of mRNA Recruitment to Ribosomes and Regulators of Translation

    Anne-Claude Gingras;Brian Raught;Nahum Sonenberg

  • The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

    Dattatreya Mellacheruvu;Zachary Wright;Amber L. Couzens;Jean Philippe Lambert

  • Regulation of translation initiation by FRAP/mTOR

    Anne-Claude Gingras;Brian Raught;Nahum Sonenberg

  • Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

    Anne-Claude Gingras;Steven P. Gygi;Brian Raught;Roberto D. Polakiewicz

  • A global genetic interaction network maps a wiring diagram of cellular function

    Michael Costanzo;Benjamin VanderSluis;Elizabeth N. Koch;Anastasia Baryshnikova

  • Hierarchical phosphorylation of the translation inhibitor 4E-BP1

    Anne-Claude Gingras;Brian Raught;Steven P. Gygi;Steven P. Gygi;Anna Niedzwiecka

  • A common open representation of mass spectrometry data and its application to proteomics research

    Patrick G A Pedrioli;Jimmy K Eng;Robert Hubley;Mathijs Vogelzang

  • Analysis of protein complexes using mass spectrometry

    Anne-Claude Gingras;Anne-Claude Gingras;Matthias Gstaiger;Brian Raught;Brian Raught;Ruedi Aebersold

  • Computational prediction of proteotypic peptides for quantitative proteomics

    Parag Mallick;Markus Schirle;Sharon S Chen;Mark R Flory

  • The target of rapamycin (TOR) proteins

    Brian Raught;Anne-Claude Gingras;Nahum Sonenberg

  • Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

    Valérie Lallemand-Breitenbach;Marion Jeanne;Shirine Benhenda;Rihab Nasr

  • The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity

    David Shahbazian;Philippe P Roux;Virginie Mieulet;Michael S Cohen

  • Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases

    Brian Raught;Franck Peiretti;Anne-Claude Gingras;Mark Livingstone

  • A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.

    Gagan D. Gupta;Étienne Coyaud;João Gonçalves;Bahareh A. Mojarad

  • A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein

    Marilyn Goudreault;Lisa M. D'Ambrosio;Lisa M. D'Ambrosio;Michelle J. Kean;Michelle J. Kean;Michael J. Mullin

  • Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress

    C. Bassi;J. Ho;T. Srikumar;Rjo J. O. Dowling

  • A Novel Functional Human Eukaryotic Translation Initiation Factor 4G

    Alessandra Gradi;Hiroaki Imataka;Yuri V. Svitkin;Eran Rom

  • miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4–NOT

    Marc R Fabian;Maja K Cieplak;Filipp Frank;Masahiro Morita;Masahiro Morita

  • Activation of GCN2 in UV-Irradiated Cells Inhibits Translation

    Jing Deng;Heather P. Harding;Brian Raught;Anne-Claude Gingras

  • eIF4E activity is regulated at multiple levels

    Brian Raught;Anne-Claude Gingras

Frequent Co-Authors

Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Linda Z. Penn
Linda Z. Penn University of Toronto
Laurence Pelletier
Laurence Pelletier Lunenfeld-Tanenbaum Research Institute
Nahum Sonenberg
Nahum Sonenberg McGill University
Cheryl H. Arrowsmith
Cheryl H. Arrowsmith Structural Genomics Consortium
Aaron D. Schimmer
Aaron D. Schimmer Princess Margaret Cancer Centre
Paul C. Boutros
Paul C. Boutros University of California, Los Angeles
John H. Brumell
John H. Brumell University of Toronto
Alexey I. Nesvizhskii
Alexey I. Nesvizhskii University of Michigan–Ann Arbor

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