World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
89
Citations
32876
World Ranking
12578
National Ranking
6435

Overview

Charles H. Lang is affiliated with Pennsylvania State University in the United States. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant emphasis on Molecular Biology, Cardiology and Cardiovascular Medicine, Physiology, Rehabilitation, and Nutrition and Dietetics.

The scientist's recent publications cover multiple aspects of muscle physiology, sepsis, alcohol effects on muscle, and biological processes under altered physiological conditions. Notable papers include:

  • Mechanical loading recovers bone but not muscle lost during unloading, 2020, npj Microgravity
  • Binge alcohol disrupts skeletal muscle core molecular clock independent of glucocorticoids, 2021, American Journal of Physiology-Endocrinology and Metabolism
  • Contractility and Myofibrillar Content in Skeletal Muscle are Decreased During Post-Sepsis Recovery, But Not During the Acute Phase of Sepsis, 2020, Shock
  • IMPORTANCE OF THE INNATE IMMUNE RESPONSE IN SKELETAL MUSCLE TO SEPSIS-INDUCED ALTERATIONS IN PROTEIN BALANCE, 2022, Shock
  • Alcohol Acutely Antagonizes Refeeding-Induced Alterations in the Rag GTPase-Ragulator Complex in Skeletal Muscle, 2021, Nutrients

Their research topics include:

  • Muscle Physiology and Disorders
  • Spaceflight effects on biology
  • Exercise and Physiological Responses
  • Cardiovascular Function and Risk Factors
  • PI3K/AKT/mTOR signaling in cancer
  • Nutrition and Health in Aging
  • Cardiovascular Effects of Exercise

Frequent co-authors collaborating with Charles H. Lang are:

  • Henry J. Donahue
  • Jennifer L. Steiner
  • David V. Rasicci
  • Jinghua Ge
  • Neil B. Wood

Their research has been published predominantly in several key venues, including:

  • Shock
  • bioRxiv (Cold Spring Harbor Laboratory)
  • npj Microgravity
  • American Journal of Physiology-Endocrinology and Metabolism
  • Nutrients

The fields of study reflected in their publications highlight an interdisciplinary approach combining molecular biology with cardiovascular and muscle physiology, focusing on clinical and physiological responses to sepsis, alcohol exposure, and physical unloading. Their work contributes to understanding the molecular and physiological changes in skeletal muscle under various stressors and the innate immune response during disease states. The integration of topics such as spaceflight effects and aging suggests a broad application of their research in health and disease contexts.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output.

    Charles H. Lang;Cornel Dobrescu;Gregory J. Bagby

  • Handbook of Learning Analytics

    Charles Lang;George Siemens;Alyssa Wise;Dragan Gasevic

  • TNF-α impairs heart and skeletal muscle protein synthesis by altering translation initiation

    Charles H. Lang;Robert A. Frost;Angus C. Nairn;David A. MacLean

  • Lipopolysaccharide regulates proinflammatory cytokine expression in mouse myoblasts and skeletal muscle

    Robert A. Frost;Gerald J. Nystrom;Charles H. Lang

  • Contribution of insulin to the translational control of protein synthesis in skeletal muscle by leucine

    Joshua C. Anthony;Charles H. Lang;Stephen J. Crozier;Tracy G. Anthony

  • Cardiac output and redistribution of organ blood flow in hypermetabolic sepsis

    C. H. Lang;G. J. Bagby;J. L. Ferguson;J. J. Spitzer

  • Regulation of muscle protein synthesis during sepsis and inflammation

    Charles H. Lang;Robert A. Frost;Thomas C. Vary

  • Endotoxin stimulates in vivo expression of inflammatory cytokines tumor necrosis factor alpha, interleukin-1beta, -6, and high-mobility-group protein-1 in skeletal muscle.

    Charles H. Lang;Christine Silvis;Nobuko Deshpande;Gerald Nystrom

  • Regulation of insulin-like growth factor-I (IGF-I) and IGF-binding proteins by tumor necrosis factor

    Jie Fan;D. Char;G. J. Bagby;M. C. Gelato

  • Protein kinase B/Akt: a nexus of growth factor and cytokine signaling in determining muscle mass

    Robert A. Frost;Charles H. Lang

  • Orally Administered Leucine Enhances Protein Synthesis in Skeletal Muscle of Diabetic Rats in the Absence of Increases in 4E-BP1 or S6K1 Phosphorylation

    Joshua C. Anthony;Ali K. Reiter;Tracy G. Anthony;Stephen J. Crozier

  • Hindlimb casting decreases muscle mass in part by proteasome-dependent proteolysis but independent of protein synthesis

    Brian J. Krawiec;Robert A. Frost;Thomas C. Vary;Leonard S. Jefferson

  • Increased protein synthesis after acute IGF-I or insulin infusion is localized to muscle in mice

    Tor H. Bark;Margaret A. McNurlan;Charles H. Lang;Peter J. Garlick

  • Alterations in the growth hormone-insulin-like growth factor axis in insulin dependent diabetes mellitus.

    A. Bereket;C. H. Lang;T. A. Wilson

  • Transient exposure of human myoblasts to tumor necrosis factor-alpha inhibits serum and insulin-like growth factor-I stimulated protein synthesis.

    Robert A. Frost;Charles H. Lang;Marie C. Gelato

  • Differential tissue regulation of insulin-like growth factor-I content and binding proteins after endotoxin.

    Jie Fan;Patricia E. Molina;Marie C. Gelato;Charles H. Lang

  • Contribution of different organs to increased glucose consumption after endotoxin administration.

    K Mészáros;C H Lang;G J Bagby;J J Spitzer

  • Insulin-like growth factor binding protein-3 proteolysis in children with insulin-dependent diabetes mellitus: a possible role for insulin in the regulation of IGFBP-3 protease activity

    Abdullah Bereket;Charles H. Lang;Sandra L. Blethen;Jie Fan

  • IL-1 receptor antagonist attenuates sepsis-induced alterations in the IGF system and protein synthesis

    Charles H. Lang;Jie Fan;Robert Cooney;Thomas C. Vary

Frequent Co-Authors

Scot R. Kimball
Scot R. Kimball Pennsylvania State University
Leonard S. Jefferson
Leonard S. Jefferson Pennsylvania State University
Steve Nelson
Steve Nelson Louisiana State University Health Sciences Center New Orleans
Philippe Pierre
Philippe Pierre Aix-Marseille University
Jack R. Wands
Jack R. Wands Brown University
Angus C. Nairn
Angus C. Nairn Yale University
Neil T. Heffernan
Neil T. Heffernan Worcester Polytechnic Institute
Daniel G. Remick
Daniel G. Remick Boston University
Alexander N. Hristov
Alexander N. Hristov Pennsylvania State University
Jennifer L. Hochschild
Jennifer L. Hochschild Harvard University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring medicine in the USA opens up diverse career options through online education. For those interested in a direct patient care role, a lpn program provides a fast track into nursing and is ideal for entry-level professionals seeking hands-on experience or planning to advance further in healthcare.

If you wish to specialize, online msn pmhnp programs prepare nurses for advanced roles in psychiatric and mental health care. These programs focus on providing critical mental health services and often offer flexible, accelerated study pathways.

For those drawn to the leadership and business side of healthcare, an accredited health administration degree empowers graduates to manage hospitals, clinics, and public health organizations. This is an excellent path for individuals interested in policy, management, or healthcare operations.

At the graduate level, understanding mha degree cost is essential for those pursuing advanced healthcare administration roles. Comparing tuition, financial aid, and program outcomes helps prospective students make informed choices as they map their professional journeys in medicine and healthcare.

Best Scientists Citing Charles H. Lang

Trending Scientists

Recently Published Articles