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Molecular Biology

D-Index
45
Citations
8599
World Ranking
2856
National Ranking
52

Overview

Nicolas Mermod is a researcher affiliated with the University of Lausanne in Switzerland. Their work primarily spans the field of Biochemistry, Genetics, and Molecular Biology, with a focus on Molecular Biology, Genetics, Cancer Research, Oncology, and Biotechnology. This multidisciplinary approach is reflected across their publication record and research topics.

The scholarly output of Nicolas Mermod includes papers published in several peer-reviewed venues. Notable publication venues include:

  • Biotechnology and Bioengineering
  • Metabolic Engineering
  • Journal of Biomechanics
  • Journal of Biotechnology
  • Cancer Research

Recent papers published by Mermod and collaborators cover a range of topics related to protein production, gene transfer, and cell physiology. Selected publications include:

  • Overexpression of transcription factor Foxa1 and target genes remediate therapeutic protein production bottlenecks in Chinese hamster ovary cells, 2020, Biotechnology and Bioengineering
  • Transient vitamin B5 starving improves mammalian cell homeostasis and protein production, 2020, Metabolic Engineering
  • Influence of cytoskeleton organization on recombinant protein expression by CHO cells, 2020, Biotechnology and Bioengineering
  • Rheological properties of skeletal muscles in a Duchenne muscular dystrophy murine model before and after autologous cell therapy, 2021, Journal of Biomechanics
  • PiggyBac transposase and transposon derivatives for gene transfer targeting the ribosomal DNA loci of CHO cells, 2021, Journal of Biotechnology

The research topics explored by Mermod include viral infectious diseases and gene expression in insects, virus-based gene therapy research, protein purification and stability, CRISPR and genetic engineering, transgenic plants and applications, peroxisome proliferator-activated receptors, and metabolism and genetic disorders.

  • Viral Infectious Diseases and Gene Expression in Insects
  • Virus-based gene therapy research
  • Protein purification and stability
  • CRISPR and Genetic Engineering
  • Transgenic Plants and Applications
  • Peroxisome Proliferator-Activated Receptors
  • Metabolism and Genetic Disorders

Nicolas Mermod collaborates frequently with several researchers in the field. The most frequent co-authors include:

  • Valérie Le Fourn
  • Pierre-Alain Girod
  • Igor Fisch
  • Jacqueline Masternak
  • Iris Bodenmann

Best Publications

  • The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain

    Nicolas Mermod;Edward A. O'Neill;Thomas J. Kelly;Robert Tjian

  • A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs

    Claudio Santoro;Claudio Santoro;Nicolas Mermod;Philip C. Andrews;Robert Tjian

  • Statistical significance of quantitative PCR

    Yann Karlen;Alan McNair;Sébastien Perseguers;Christian Mazza

  • Enhancer binding factors AP-4 and AP-1 act in concert to activate SV40 late transcription in vitro

    Nicolas Mermod;Trevor J. Williams;Robert Tjian

  • Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity.

    Y. F. Hu;Bernhard Luscher;A. Admon;N. Mermod

  • High-throughput SELEX SAGE method for quantitative modeling of transcription-factor binding sites.

    Emmanuelle Roulet;Stéphane Busso;Anamaria A. Camargo;Andrew J.G. Simpson

  • Genome-wide prediction of matrix attachment regions that increase gene expression in mammalian cells

    Pierre-Alain Girod;Pierre-Alain Girod;Duc-Quang Nguyen;Duc-Quang Nguyen;Duc-Quang Nguyen;David Calabrese;David Calabrese;Stefania Puttini

  • Development of stable cell lines for production or regulated expression using matrix attachment regions

    Monique Zahn-Zabal;Michel Kobr;Pierre-Alain Girod;Markus Imhof

  • CHO cell engineering to prevent polypeptide aggregation and improve therapeutic protein secretion.

    Valérie Le Fourn;Pierre-Alain Girod;Montse Buceta;Alexandre Regamey

  • A proline-rich TGF-beta-responsive transcriptional activator interacts with histone H3.

    A Alevizopoulos;Y Dusserre;M Tsai-Pflugfelder;T von der Weid

  • Use of the chicken lysozyme 5' matrix attachment region to generate high producer CHO cell lines.

    Pierre-Alain Girod;Monique Zahn-Zabal;Nicolas Mermod

  • Structure-Function Characterization and Optimization of a Plant-Derived Antibacterial Peptide

    Mougli Suarez;Marisa Haenni;Stéphane Canarelli;Florian Fisch

  • Regulation of gene expression by interferons: control of H-2 promoter responses.

    Bette Korber;Nicolas Mermod;Leroy Hood;Iwona T Stroynowski

  • Regulatory circuits controlling transcription of TOL plasmid operon encoding meta-cleavage pathway for degradation of alkylbenzoates by Pseudomonas.

    J. L. Ramos;N. Mermod;K. N. Timmis

  • An autoregulatory loop controlling CYP1A1 gene expression: role of H(2)O(2) and NFI.

    Yannick Morel;Nicolas Mermod;Robert Barouki

  • Vector for regulated expression of cloned genes in a wide range of gram-negative bacteria.

    N Mermod;J L Ramos;P R Lehrbach;K N Timmis

  • Transforming growth factor-beta: the breaking open of a black box.

    Athanassios Alevizopoulos;Nicolas Mermod

  • Protein-protein interactions between adenovirus DNA polymerase and nuclear factor I mediate formation of the DNA replication preinitiation complex.

    Mei Chen;N. Mermod;M. S. Horwitz

  • Sustained Transgene Expression Using MAR Elements

    Niamh Harraghy;Armelle Gaussin;Nicolas Mermod

  • An activation-independent role of transcription factors in insulator function

    Geneviève Fourel;Cécile Boscheron;Émanuelle Revardel;Éléonore Lebrun

Frequent Co-Authors

Philipp Bucher
Philipp Bucher École Polytechnique Fédérale de Lausanne
Jacques Schrenzel
Jacques Schrenzel University of Geneva
Florian M. Wurm
Florian M. Wurm École Polytechnique Fédérale de Lausanne
Jacques S. Beckmann
Jacques S. Beckmann University of Lausanne
Ruth Freitag
Ruth Freitag University of Bayreuth
Walter Wahli
Walter Wahli University of Lausanne
Blaise Corthésy
Blaise Corthésy University Hospital of Lausanne
Robert Tjian
Robert Tjian University of California, Berkeley
Ioannis Xenarios
Ioannis Xenarios University of Lausanne
Jozef Adamcik
Jozef Adamcik ETH Zurich

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