World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
92
Citations
22855
World Ranking
11468
National Ranking
5877

Research.com Recognitions

  • 2010 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Jeffrey C. Lotz is affiliated with the University of California, San Francisco in the United States. Their research primarily focuses on medicine, with specific contributions across pharmacology, pathology and forensic medicine, biomedical engineering, surgery, and psychiatry and mental health.

The scientist's work centers on topics such as musculoskeletal pain and rehabilitation, spine and intervertebral disc pathology, medical imaging and analysis, fibromyalgia and chronic fatigue syndrome research, health systems including economic evaluations and quality of life, orthopaedic implants and arthroplasty, as well as spinal fractures and fixation techniques.

Frequent publication venues for their work include:

  • JOR Spine
  • European Spine Journal
  • Pain Medicine
  • The Spine Journal
  • bioRxiv (Cold Spring Harbor Laboratory)

Regular collaborators in their research include:

  • Conor O'Neill
  • Aaron J. Fields
  • Jeannie F. Bailey
  • Wolf Mehling
  • Patricia Zheng

Significant recent publications by Jeffrey C. Lotz comprise:

  • Development of a standardized histopathology scoring system for human intervertebral disc degeneration: an Orthopaedic Research Society Spine Section Initiative, 2021, JOR Spine
  • Vertebrogenic Pain: A Paradigm Shift in Diagnosis and Treatment of Axial Low Back Pain, 2022, Pain Medicine
  • Automatic Vertebral Body Segmentation Based on Deep Learning of Dixon Images for Bone Marrow Fat Fraction Quantification, 2020, Frontiers in Endocrinology
  • The contributions of cartilage endplate composition and vertebral bone marrow fat to intervertebral disc degeneration in patients with chronic low back pain, 2022, European Spine Journal
  • Biomechanical changes in the lumbar spine following spaceflight and factors associated with postspaceflight disc herniation, 2021, The Spine Journal

Jeffrey C. Lotz has been recognized as a Fellow of the Indian National Academy of Engineering (INAE), awarded in 2010.

Best Publications

  • Compression-induced degeneration of the intervertebral disc: an in vivo mouse model and finite-element study.

    Jeffrey C. Lotz;Olivier K. Colliou;Jennie R. Chin;Neil A. Duncan

  • Intervertebral disc cell therapy for regeneration: mesenchymal stem cell implantation in rat intervertebral discs.

    Gwen Crevensten;Andrew J. L. Walsh;Dheera Ananthakrishnan;Paul Page

  • Intervertebral disc cell death is dependent on the magnitude and duration of spinal loading.

    Jeffrey C. Lotz;Jennie R. Chin

  • Mechanical properties of trabecular bone from the proximal femur: a quantitative CT study.

    Jeffrey C. Lotz;Tobin N. Gerhart;Wilson C. Hayes

  • Biomechanical testing of posterior atlantoaxial fixation techniques.

    Robert P. Melcher;Christian M. Puttlitz;Frank S. Kleinstueck;Jeffrey C. Lotz

  • Fracture prediction for the proximal femur using finite element models: Part I--Linear analysis.

    J. C. Lotz;E. J. Cheal;Wilson C. Hayes

  • Stress distributions within the proximal femur during gait and falls: Implications for osteoporotic fracture

    J. C. Lotz;E. J. Cheal;W. C. Hayes

  • A musculoskeletal model for the lumbar spine.

    Miguel Christophy;Nur Adila Faruk Senan;Jeffrey C. Lotz;Oliver M. O’Reilly

  • Pathobiology of Modic changes

    Stefan Dudli;Aaron J. Fields;Dino Samartzis;Jaro Karppinen

  • In vivo growth factor treatment of degenerated intervertebral discs.

    Andrew J. L. Walsh;David S. Bradford;Jeffrey C. Lotz

  • Animal models of intervertebral disc degeneration: lessons learned.

    Jeffrey C Lotz

  • Biological response of the intervertebral disc to dynamic loading

    Andrew J.L. Walsh;Jeffrey C. Lotz

  • The use of quantitative computed tomography to estimate risk of fracture of the hip from falls

    Jeffrey C. Lotz;Wilson C. Hayes

  • Intervertebral Disc Degeneration: The Role of the Mitochondrial Pathway in Annulus Fibrosus Cell Apoptosis Induced by Overload

    François Rannou;Tzong-Shyuan Lee;Rui-Hai Zhou;Jennie Chin

  • Mechanical properties of metaphyseal bone in the proximal femur

    Jeffrey C. Lotz;Jeffrey C. Lotz;Tobin N. Gerhart;Tobin N. Gerhart;Wilson C. Hayes;Wilson C. Hayes

  • Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs

    Jeffrey C. Lotz;Olivier K. Colliou;David S. Bradford

  • Tenascin-X deficiency mimics Ehlers-Danlos syndrome in mice through alteration of collagen deposition.

    Jau Ren Mao;Glen Taylor;Willow B Dean;Willow B Dean;Diane R Wagner

  • Multiple differentiation capacity of STRO-1+/CD146+ PDL mesenchymal progenitor cells.

    Jinping Xu;Wei Wang;Yvonne Kapila;Jeffrey Lotz

  • The role of the vertebral end plate in low back pain.

    J. C. Lotz;A. J. Fields;E. C. Liebenberg

  • Chondrogenic Differentiation of Human Mesenchymal Stem Cells in Three-Dimensional Alginate Gels

    Jinping Xu;Wei Wang;Matt Ludeman;Kevin Cheng

Frequent Co-Authors

Chris J. Diederich
Chris J. Diederich University of California, San Francisco
Sigurd Berven
Sigurd Berven University of California, San Francisco
Jaro Karppinen
Jaro Karppinen University of Oulu
Holger Thiele
Holger Thiele Leipzig University
Sharmila Majumdar
Sharmila Majumdar University of California, San Francisco
Alan R. Hargens
Alan R. Hargens University of California, San Diego
Ingo Eitel
Ingo Eitel University of Lübeck
Gerd Hasenfuss
Gerd Hasenfuss University of Göttingen
Wilson C. Hayes
Wilson C. Hayes Independent Scientist / Consultant, US
Christian M. Puttlitz
Christian M. Puttlitz Colorado State University

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