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Molecular Biology

D-Index
46
Citations
22369
World Ranking
2769
National Ranking
190

Overview

Manfred Gossen is affiliated with Charité - University Medicine Berlin in Germany. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with significant focus on Molecular Biology, Genetics, Oncology, Surgery, and Cell Biology.

The scientist's work encompasses a number of main topics including RNA Interference and Gene Delivery, Virus-based gene therapy research, Cellular Mechanics and Interactions, 3D Printing in Biomedical Research, CRISPR and Genetic Engineering, Advanced Biosensing and Bioanalysis Techniques, and Tissue Engineering and Regenerative Medicine.

Frequent collaborators include Hanieh Moradian, Andreas Lendlein, Hans-Dieter Volk, Norman Michael Drzeniek, and Marko Schwestka.

Manfred Gossen has published in various journals, with frequent appearances in these venues:

  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Therapy - Nucleic Acids
  • International Journal of Molecular Sciences
  • Nature Communications

Recent papers authored or co-authored by Manfred Gossen include:

  • Chemical modification of uridine modulates mRNA-mediated proinflammatory and antiviral response in primary human macrophages, 2022, Molecular Therapy - Nucleic Acids
  • mRNA Transfection-Induced Activation of Primary Human Monocytes and Macrophages: Dependence on Carrier System and Nucleotide Modification, 2020, Scientific Reports
  • Efficient generation of osteoclasts from human induced pluripotent stem cells and functional investigations of lethal CLCN7-related osteopetrosis, 2020, Journal of Bone and Mineral Research
  • Bio-instructive hydrogel expands the paracrine potency of mesenchymal stem cells, 2021, Biofabrication
  • Dissecting the influence of cellular senescence on cell mechanics and extracellular matrix formation in vitro, 2022, Aging Cell

Best Publications

  • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

    Manfred Gossen;Hermann Bujard

  • Transcriptional activation by tetracyclines in mammalian cells

    Manfred Gossen;Sabine Freundlieb;Gabriele Bender;Gerhard Müller

  • Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system.

    D Resnitzky;M Gossen;H Bujard;S I Reed

  • Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice.

    Andreas Kistner;Manfred Gossen;Frank Zimmermann;Jasna Jerecic

  • Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter

    P A Furth;L St Onge;H Böger;P Gruss

  • Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential

    Udo Baron;Manfred Gossen;Hermann Bujard

  • Co-regulation of two gene activities by tetracycline via a bidirectional promoter

    Udo Baron;Sabine Freundlieb;Manfred Gossen;Hermann Bujard

  • Global analysis of cellular protein translation by pulsed SILAC

    Björn Schwanhäusser;Manfred Gossen;Gunnar Dittmar;Matthias Selbach

  • Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements

    Manfred Gossen;Angelika L. Bonin;Hermann Bujard

  • Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters

    Hermann Bujard;Manfred Gossen;Jochen G. Salfeld;Jeffrey W. Voss

  • Methods for regulating gene expression

    Hermann Bujard;Manfred Gossen

  • A chimeric transactivator allows tetracycline-responsive gene expression in whole plants

    Pamela Weinmann;Manfred Gossen;Wolfgang Hillen;Hermann Bujard

  • Displacement of housekeeping proteasome subunits by MHC-encoded LMPs: a newly discovered mechanism for modulating the multicatalytic proteinase complex.

    Klaus Früh;Manfred Gossen;Kena Wang;Hermann Bujard

  • Tetracycline-regulated transcriptional inhibitors

    Hermann Bujard;Manfred Gossen

  • Studying Gene Function in Eukaryotes by Conditional Gene Inactivation

    Manfred Gossen;Hermann Bujard

  • Inducible gene expression systems for higher eukaryotic cells.

    Manfred Gossen;Angelika L Bonin;Sabine Freundlieb;Hermann Bujard

  • Improved Tet-responsive promoters with minimized background expression

    Rainer Loew;Niels Heinz;Mathias Hampf;Hermann Bujard

  • A Drosophila homolog of the yeast origin recognition complex

    Manfred Gossen;Daniel T. S. Pak;Stig K. Hansen;Jairaj K. Acharya

  • Stimulation of cyclin-dependent kinase activity and G1- to S-phase transition in human lymphocytes by the human T-cell leukemia/lymphotropic virus type 1 Tax protein.

    Iris Schmitt;Oliver Rosin;Peter Rohwer;Manfred Gossen

  • Anhydrotetracycline, a novel effector for tetracycline controlled gene expression systems in eukaryotic cells.

    Manfred Gossen;Hermann Bujard

Frequent Co-Authors

Hermann Bujard
Hermann Bujard Heidelberg University
Andreas Lendlein
Andreas Lendlein Helmholtz-Zentrum Hereon
Volkmar Falk
Volkmar Falk Charité - University Medicine Berlin
Michael R. Botchan
Michael R. Botchan University of California, Berkeley
Wolfgang Hillen
Wolfgang Hillen University of Erlangen-Nuremberg
Barbara Steiner
Barbara Steiner Charité - University Medicine Berlin
Christine Winter
Christine Winter Charité - University Medicine Berlin
Petra Reinke
Petra Reinke Berlin-Brandenburger Centrum für Regenerative Therapien
Uwe Kornak
Uwe Kornak University of Göttingen
Zsuzsanna Izsvák
Zsuzsanna Izsvák Max Delbrück Center for Molecular Medicine

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