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Molecular Biology

D-Index
84
Citations
37654
World Ranking
863
National Ranking
69

Research.com Recognitions

  • 2014 - Robert Koch Gold Medal

Overview

Hermann Bujard was affiliated with Heidelberg University in Germany. Their research focused extensively on medicine, with particular attention to immunology and microbiology.

The main topics covered in their work included:

  • Mosquito-borne diseases and control
  • Malaria Research and Control
  • HIV Research and Treatment
  • Invertebrate Immune Response Mechanisms
  • Enzyme Structure and Function

Some of the subfields that featured prominently in Bujard's research were public health, environmental and occupational health, virology, immunology, and materials chemistry.

Two recent papers illustrate the areas of scientific inquiry pursued:

  • Immunization with full-length Plasmodium falciparum merozoite surface protein 1 is safe and elicits functional cytophilic antibodies in a randomized first-in-human trial (2020), published in npj Vaccines
  • Structure of the merozoite surface protein 1 from Plasmodium falciparum (2021), published in Science Advances

These publications addressed topics related to malaria parasite surface proteins and vaccine development, contributing data relevant to infectious disease immunology and structural biology.

The scientist frequently collaborated with several coauthors, including:

  • Michael Lanzer (2 publications)
  • Antje Blank (1 publication)
  • Kristin Fürle (1 publication)
  • Anja Jäschke (1 publication)
  • Gerd Mikus (1 publication)

Bujard's research appeared mainly in the journals npj Vaccines and Science Advances, reflecting a focus on vaccine research and advances in biomedical science.

In recognition of their contributions, Hermann Bujard was awarded the Robert Koch Gold Medal in 2014.

Best Publications

  • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

    Manfred Gossen;Hermann Bujard

  • Transcriptional activation by tetracyclines in mammalian cells

    Manfred Gossen;Sabine Freundlieb;Gabriele Bender;Gerhard Müller

  • Independent and Tight Regulation of Transcriptional Units in Escherichia Coli Via the LacR/O, the TetR/O and AraC/I1-I2 Regulatory Elements

    Rolf Lutz;Hermann Bujard

  • Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system.

    D Resnitzky;M Gossen;H Bujard;S I Reed

  • Exploring the sequence space for tetracycline-dependent transcriptional activators: Novel mutations yield expanded range and sensitivity

    Stefanie Urlinger;Udo Baron;Marion Thellmann;Mazahir T. Hasan

  • Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice.

    Andreas Kistner;Manfred Gossen;Frank Zimmermann;Jasna Jerecic

  • Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter

    P A Furth;L St Onge;H Böger;P Gruss

  • System-Driven and Oscillator-Dependent Circadian Transcription in Mice with a Conditionally Active Liver Clock

    Benoît Kornmann;Olivier Schaad;Hermann Bujard;Joseph S. Takahashi

  • Tet repressor-based system for regulated gene expression in eukaryotic cells: principles and advances.

    Udo Baron;Hermann Bujard

  • Organization of transcriptional signals in plasmids pBR322 and pACYC184

    Dietrich Stuber;Hermann Bujard

  • Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential

    Udo Baron;Manfred Gossen;Hermann Bujard

  • Co-regulation of two gene activities by tetracycline via a bidirectional promoter

    Udo Baron;Sabine Freundlieb;Manfred Gossen;Hermann Bujard

  • Promoters largely determine the efficiency of repressor action

    Michael Lanzer;Hermann Bujard

  • Physical interaction between heat shock proteins DnaK, DnaJ, and GrpE and the bacterial heat shock transcription factor σ32

    Jürgen Gamer;Hermann Bujard;Bernd Bukau

  • A T5 promoter-based transcription-translation system for the analysis of proteins in vitro and in vivo

    Hermann Bujard;Reiner Gentz;Michael Lanzer;Dietrich Stueber

  • The Potential for β-Structure in the Repeat Domain of Tau Protein Determines Aggregation, Synaptic Decay, Neuronal Loss, and Coassembly with Endogenous Tau in Inducible Mouse Models of Tauopathy

    Maria-Magdalena Mocanu;Astrid Nissen;Katrin Eckermann;Inna Khlistunova

  • Promoters of Escherichia coli: a hierarchy of in vivo strength indicates alternate structures.

    U Deuschle;W Kammerer;R Gentz;H Bujard

  • A tetracycline controlled activation/repression system with increased potential for gene transfer into mammalian cells

    Sabine Freundlieb;Christiane Schirra‐Müller;Hermann Bujard

  • Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements

    Manfred Gossen;Angelika L. Bonin;Hermann Bujard

  • A cycle of binding and release of the DnaK, DnaJ and GrpE chaperones regulates activity of the Escherichia coli heat shock transcription factor sigma32.

    J. Gamer;G. Multhaup;T. Tomoyasu;J. S. McCarty

Frequent Co-Authors

Manfred Gossen
Manfred Gossen Charité - University Medicine Berlin
Klaus Früh
Klaus Früh Oregon Health & Science University
Wolfgang Hillen
Wolfgang Hillen University of Erlangen-Nuremberg
Andrea Crisanti
Andrea Crisanti University of Padua
Reiner L. Gentz
Reiner L. Gentz Gentz Biopharmaceutical Consulting
Eva-Maria Mandelkow
Eva-Maria Mandelkow German Center for Neurodegenerative Diseases
Jacek Biernat
Jacek Biernat German Center for Neurodegenerative Diseases
Gabriele M. Rune
Gabriele M. Rune Universität Hamburg
Michael Lanzer
Michael Lanzer University Hospital Heidelberg
Ulrike Protzer
Ulrike Protzer Technical University of Munich

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