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Biology and Biochemistry
Germany
2026

D-Index & Metrics

Molecular Biology

D-Index
131
Citations
56809
World Ranking
186
National Ranking
14

Biology and Biochemistry

D-Index
134
Citations
58302
World Ranking
365
National Ranking
24

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2025 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2023 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2005 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Biochemistry and Biophysics
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Bernd Bukau is affiliated with the German Cancer Research Center in Germany and has contributed extensively to the field of biochemistry, genetics, and molecular biology. Their research spans a variety of subfields, including molecular biology, cell biology, materials chemistry, neurology, and physiology.

Their work addresses several main topics such as heat shock proteins research, RNA and protein synthesis mechanisms, RNA modifications and cancer, protein structure and dynamics, endoplasmic reticulum stress and disease, RNA research and splicing, and enzyme structure and function.

Recent publications by Bernd Bukau cover a range of high-impact journals and significant topics:

  • Molecular dissection of amyloid disaggregation by human HSP70, 2020, Nature
  • HSP40 proteins use class-specific regulation to drive HSP70 functional diversity, 2020, Nature
  • Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species, 2020, Journal of Biological Chemistry
  • Selective 40S Footprinting Reveals Cap-Tethered Ribosome Scanning in Human Cells, 2020, Molecular Cell
  • Processive extrusion of polypeptide loops by a Hsp100 disaggregase, 2020, Nature

Frequent coauthors they have collaborated with include Günter Krämer, Anne S. Wentink, Axel Mogk, Sander J. Tans, and Kai Fenzl.

Bernd Bukau often publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature, Journal of Molecular Biology, Nature Communications, and The EMBO Journal.

The scientist is recognized for membership in notable scientific communities, including being a member of the European Molecular Biology Organization (EMBO) and the German National Academy of Sciences Leopoldina for contributions in biochemistry and biophysics awarded in 2005.

Best Publications

  • The Hsp70 and Hsp60 chaperone machines.

    Bernd Bukau;Arthur L Horwich

  • Hsp70 chaperones: cellular functions and molecular mechanism.

    Matthias P. Mayer;Bernd Bukau

  • Molecular Chaperones and Protein Quality Control

    Bernd Bukau;Jonathan Weissman;Arthur Horwich;Arthur Horwich

  • Cellular strategies for controlling protein aggregation

    Jens Tyedmers;Axel Mogk;Bernd Bukau

  • Substrate specificity of the DnaK chaperone determined by screening cellulose‐bound peptide libraries

    Stefan Rüdiger;Lothar Germeroth;Jens Schneider‐Mergener;Bernd Bukau

  • The Hsp70 chaperone network

    Rina Rosenzweig;Nadinath B. Nillegoda;Matthias P. Mayer;Bernd Bukau;Bernd Bukau

  • DnaK, DnaJ and GrpE form a cellular chaperone machinery capable of repairing heat-induced protein damage.

    H. Schröder;T. Langer;F.U. Hartl;B. Bukau

  • Sequential mechanism of solubilization and refolding of stable protein aggregates by a bichaperone network

    Pierre Goloubinoff;Axel Mogk;Anat Peres Ben Zvi;Toshifumi Tomoyasu

  • Identification of thermolabile Escherichia coli proteins: prevention and reversion of aggregation by DnaK and ClpB

    Axel Mogk;Toshifumi Tomoyasu;Pierre Goloubinoff;Stefan Rüdiger

  • Mechanism of regulation of Hsp70 chaperones by DnaJ cochaperones

    Thomas Laufen;Matthias P. Mayer;Christian Beisel;Dagmar Klostermeier

  • The ATP hydrolysis-dependent reaction cycle of the Escherichia coli Hsp70 system DnaK, DnaJ, and GrpE

    A Szabo;T Langer;T Langer;H Schröder;J Flanagan

  • Trigger factor and DnaK cooperate in folding of newly synthesized proteins.

    Elke Deuerling;Agnes Schulze-Specking;Toshifumi Tomoyasu;Axel Mogk

  • The heat shock response of Escherichia coli

    Florence Arsène;Toshifumi Tomoyasu;Bernd Bukau

  • Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms.

    Alexander Buchberger;Bernd Bukau;Thomas Sommer

  • Getting Newly Synthesized Proteins into Shape

    Bernd Bukau;Elke Deuerling;Christine Pfund;Elizabeth A Craig

  • The role of ATP in the functional cycle of the DnaK chaperone system

    John S. McCarty;Alexander Buchberger;Alexander Buchberger;Jochen Reinstein;Bernd Bukau;Bernd Bukau

  • The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins

    Günter Kramer;Daniel Boehringer;Nenad Ban;Bernd Bukau

  • Thermotolerance Requires Refolding of Aggregated Proteins by Substrate Translocation through the Central Pore of ClpB

    Jimena Weibezahn;Peter Tessarz;Christian Schlieker;Regina Zahn

  • Selective Ribosome Profiling Reveals the Cotranslational Chaperone Action of Trigger Factor In Vivo

    Eugene Oh;Annemarie H. Becker;Arzu Sandikci;Damon Huber

  • Escherichia coli FtsH is a membrane-bound, ATP-dependent protease which degrades the heat-shock transcription factor sigma 32.

    T. Tomoyasu;J. Gamer;B. Bukau;M. Kanemori

Frequent Co-Authors

Axel Mogk
Axel Mogk Heidelberg University
Matthias P. Mayer
Matthias P. Mayer Heidelberg University
Axel Mogk
Axel Mogk Heidelberg University
Stefan G.D. Rüdiger
Stefan G.D. Rüdiger Utrecht University
Rebecca C. Wade
Rebecca C. Wade Heidelberg Institute for Theoretical Studies
Holger Patzelt
Holger Patzelt Technical University of Munich
Jens Schneider-Mergener
Jens Schneider-Mergener Humboldt-Universität zu Berlin
Nenad Ban
Nenad Ban ETH Zurich
Jochen Reinstein
Jochen Reinstein Max Planck Society
Harm H. Kampinga
Harm H. Kampinga University Medical Center Groningen

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