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James Shorter

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
29754
World Ranking
3278
National Ranking
1663

James Shorter publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where James Shorter sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 255 publications — 68th percentile

68% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

James Shorter D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where James Shorter sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 84 D-Index — 84th percentile

84% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

James Shorter is affiliated with the University of Pennsylvania in the United States and has a significant body of work spanning biochemistry, genetics, molecular biology, and medicine. Their research primarily focuses on molecular biology, neurology, genetics, cell biology, and aging, with a notable emphasis on the mechanisms related to RNA and protein regulation.

The scientist's recent publications include:

  • TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A, 2022, Nature
  • FUS and TDP-43 Phases in Health and Disease, 2021, Trends in Biochemical Sciences
  • TDP-43 condensation properties specify its RNA-binding and regulatory repertoire, 2021, Cell
  • C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy, 2020, Science Translational Medicine
  • Higher-order organization of biomolecular condensates, 2021, Open Biology

The main topics covered in their work include:

  • RNA Research and Splicing
  • Amyotrophic Lateral Sclerosis Research
  • Neurogenetic and Muscular Disorders Research
  • Heat shock proteins research
  • RNA modifications and cancer
  • Prion Diseases and Protein Misfolding
  • RNA and protein synthesis mechanisms

Frequently collaborating with other researchers, James Shorter works closely with colleagues including Charlotte M. Fare, Sua Myong, Hana M. Odeh, Ryan R. Cupo, and Lin Guo. These collaborations have contributed to a diverse set of studies affecting several aspects of molecular and cellular biology.

Their research has been published extensively in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • The FASEB Journal
  • Cell Reports
  • Molecular Cell

James Shorter's body of work is anchored in the study of molecular processes involving RNA and protein interactions, particularly regarding neurodegenerative diseases. Their contributions span both fundamental and applied aspects of biochemistry and molecular biology, with relevance to neurological disorders and cellular mechanisms underlying these conditions.

Best Publications

  • Protein Phase Separation: A New Phase in Cell Biology.

    Steven Boeynaems;Steven Boeynaems;Simon Alberti;Nicolas L. Fawzi;Tanja Mittag

  • Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

    Hong Joo Kim;Nam Chul Kim;Yong Dong Wang;Emily A. Scarborough

  • Stress granules as crucibles of ALS pathogenesis

    Yun R. Li;Yun R. Li;Oliver D. King;James Shorter;Aaron D. Gitler

  • TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity

    Brian S. Johnson;David Snead;Jonathan J. Lee;J. Michael McCaffery

  • The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease

    Oliver D. King;Aaron D. Gitler;James Shorter

  • Neurodegenerative disease: models, mechanisms, and a new hope.

    Aaron D. Gitler;Paraminder Dhillon;James Shorter

  • The molecular language of membraneless organelles

    Edward Gomes;James Shorter

  • The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis

    Aaron D. Gitler;Brooke J. Bevis;James Shorter;Katherine E. Strathearn

  • Prions as adaptive conduits of memory and inheritance

    James Shorter;Susan Lindquist

  • A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways.

    Hemmo H Meyer;James G Shorter;Joachim Seemann;Darryl Pappin

  • Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS

    Zhihui Sun;Zamia Diaz;Xiaodong Fang;Michael P. Hart

  • A yeast functional screen predicts new candidate ALS disease genes

    Julien Couthouis;Michael P. Hart;James Shorter;Mariely DeJesus-Hernandez

  • RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43.

    Jacob R. Mann;Amanda M. Gleixner;Jocelyn C. Mauna;Edward Gomes

  • Golgi Architecture and Inheritance

    James Shorter;Graham Warren

  • Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains

    Lin Guo;Hong Joo Kim;Hejia Wang;John Monaghan

  • Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization

    Leeanne McGurk;Edward Gomes;Lin Guo;Jelena Mojsilovic-Petrovic

  • Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death.

    Fatima Gasset-Rosa;Shan Lu;Haiyang Yu;Cong Chen

  • RNA-binding proteins with prion-like domains in health and disease

    Alice Ford Harrison;James Shorter

  • GRASP55, a second mammalian GRASP protein involved in the stacking of Golgi cisternae in a cell-free system

    James Shorter;Rose Watson;Maria‐Eleni Giannakou;Mairi Clarke

  • The Mammalian Disaggregase Machinery: Hsp110 Synergizes with Hsp70 and Hsp40 to Catalyze Protein Disaggregation and Reactivation in a Cell-Free System

    James Shorter

Frequent Co-Authors

Aaron D. Gitler
Aaron D. Gitler Stanford University
Susan Lindquist
Susan Lindquist MIT
Graham Warren
Graham Warren Medical University of Vienna
Oliver D. King
Oliver D. King University of Massachusetts Chan Medical School
Nancy M. Bonini
Nancy M. Bonini University of Pennsylvania
Andrzej Joachimiak
Andrzej Joachimiak Argonne National Laboratory
Kim A. Caldwell
Kim A. Caldwell University of Alabama
J. Paul Taylor
J. Paul Taylor St. Jude Children's Research Hospital
Guy A. Caldwell
Guy A. Caldwell University of Alabama
Robert G. Kalb
Robert G. Kalb Northwestern University

External Links

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Best Scientists Citing James Shorter

Susan Lindquist

Susan Lindquist

MIT

Publications: 98

Aaron D. Gitler

Aaron D. Gitler

Stanford University

Publications: 60

Simon Alberti

Simon Alberti

TU Dresden

Publications: 58

Roy Parker

Roy Parker

University of Colorado Boulder

Publications: 57

Bernd Bukau

Bernd Bukau

Heidelberg University

Publications: 54

J. Paul Taylor

J. Paul Taylor

St. Jude Children's Research Hospital

Publications: 52

Tiago F. Outeiro

Tiago F. Outeiro

University of Göttingen

Publications: 47

Vladimir N. Uversky

Vladimir N. Uversky

University of South Florida

Publications: 42

Emanuele Buratti

Emanuele Buratti

International Centre for Genetic Engineering and Biotechnology

Publications: 39

Yury O. Chernoff

Yury O. Chernoff

Georgia Institute of Technology

Publications: 37

Guy A. Caldwell

Guy A. Caldwell

University of Alabama

Publications: 35

Kim A. Caldwell

Kim A. Caldwell

University of Alabama

Publications: 34

Gene W. Yeo

Gene W. Yeo

University of California, San Diego

Publications: 32

Salvador Ventura

Salvador Ventura

Autonomous University of Barcelona

Publications: 32

Julie D. Atkin

Julie D. Atkin

Macquarie University

Publications: 30

Leonard Petrucelli

Leonard Petrucelli

Mayo Clinic

Publications: 29

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