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Simon Alberti

Simon Alberti

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
42125
World Ranking
8428
National Ranking
616

Overview

Simon Alberti is a researcher affiliated with TU Dresden in Germany, specializing in Biochemistry, Genetics, and Molecular Biology. Their work is chiefly focused within the subfields of Molecular Biology, Cell Biology, Biomedical Engineering, Biophysics, and Epidemiology.

Alberti's research covers a range of main topics including:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Heat shock proteins research
  • Endoplasmic Reticulum Stress and Disease
  • Cellular Mechanics and Interactions
  • Ubiquitin and proteasome pathways

Their publication record includes papers in well-known peer-reviewed journals and publication venues, with frequent appearances in

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Molecular Cell
  • Cell
  • eLife

Notable recent papers include:

  • "Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing," 2021, Nature Reviews Molecular Cell Biology
  • "RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation," 2020, Cell
  • "Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions," 2021, Nature Communications
  • "Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions," 2022, Proceedings of the National Academy of Sciences

Their collaborative network includes frequent co-authors such as:

  • Titus M. Franzmann
  • Tuomas P. J. Knowles
  • Georg Krainer
  • Timothy J. Welsh
  • Anthony A. Hyman

These collaborations highlight engagement with a community focusing on the biophysical and molecular mechanisms underlying cellular processes, particularly stress responses and protein dynamics.

Simon Alberti's research spans complex cellular mechanisms involved in RNA behavior, protein aggregation, and disease-related pathways. The work contributes to understanding molecular basis of ageing and stress responses at a cellular level.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

    Avinash Patel;Hyun O. Lee;Louise Jawerth;Shovamayee Maharana

  • Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates.

    Simon Alberti;Simon Alberti;Amy Gladfelter;Amy Gladfelter;Tanja Mittag

  • Protein Phase Separation: A New Phase in Cell Biology.

    Steven Boeynaems;Steven Boeynaems;Simon Alberti;Nicolas L. Fawzi;Tanja Mittag

  • A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

    Jie Wang;Jeong-Mo Choi;Alex S Holehouse;Hyun O. Lee

  • A systematic survey identifies prions and illuminates sequence features of prionogenic proteins

    Simon Alberti;Randal Halfmann;Oliver King;Oliver King;Atul Kapila

  • RNA buffers the phase separation behavior of prion-like RNA binding proteins

    Shovamayee Maharana;Jie Wang;Dimitrios K. Papadopoulos;Dimitrios K. Papadopoulos;Doris Richter

  • RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation

    Jordina Guillén-Boixet;Andrii Kopach;Alex S. Holehouse;Sina Wittmann

  • ATP as a biological hydrotrope

    Avinash Patel;Liliana Malinovska;Shambaditya Saha;Jie Wang

  • Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing.

    Simon Alberti;Anthony A Hyman

  • Liquid-Liquid Phase Separation in Disease.

    Simon Alberti;Simon Alberti;Dorothee Dormann

  • Phase separation of a yeast prion protein promotes cellular fitness

    Titus M. Franzmann;Marcus Jahnel;Marcus Jahnel;Andrei Pozniakovsky;Julia Mahamid

  • Phase separation in biology.

    Simon Alberti

  • Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules

    Sonja Kroschwald;Shovamayee Maharana;Daniel Mateju;Liliana Malinovska

  • A suite of Gateway cloning vectors for high-throughput genetic analysis in Saccharomyces cerevisiae.

    Simon Alberti;Aaron D. Gitler;Susan Lindquist;Susan Lindquist

  • Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions

    Georg Krainer;Timothy J. Welsh;Jerelle A. Joseph;Jorge R. Espinosa

  • Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling

    Jens Demand;Simon Alberti;Cam Patterson;Jörg Höhfeld

  • An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function

    Daniel Mateju;Titus M Franzmann;Avinash Patel;Andrii Kopach

  • A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy

    Matthias Christoph Munder;Daniel Midtvedt;Titus Franzmann;Elisabeth Nüske

  • Amyloid-like Self-Assembly of a Cellular Compartment

    Elvan Boke;Martine Ruer;Martin Wühr;Margaret Coughlin

Frequent Co-Authors

Anthony A. Hyman
Anthony A. Hyman Max Planck Institute of Molecular Cell Biology and Genetics
Ina Poser
Ina Poser Max Planck Society
Peter St George-Hyslop
Peter St George-Hyslop Columbia University
Tuomas P. J. Knowles
Tuomas P. J. Knowles University of Cambridge
Angelo Poletti
Angelo Poletti University of Milan
Stephan W. Grill
Stephan W. Grill Max Planck Society
Oliver D. King
Oliver D. King University of Massachusetts Chan Medical School
Heath Ecroyd
Heath Ecroyd University of Wollongong
Julie D. Forman-Kay
Julie D. Forman-Kay University of Toronto

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