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D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
8375
World Ranking
18050
National Ranking
522

Overview

Heath Ecroyd is affiliated with the University of Wollongong in Australia and has a research portfolio primarily centered on biochemistry, genetics, and molecular biology, with additional contributions in medicine. Their work is extensively focused on molecular biology and related subfields such as physiology, materials chemistry, cell biology, and aging.

The main topics of research by Heath Ecroyd include:

  • Heat shock proteins research
  • Protein Structure and Dynamics
  • Alzheimer's disease research and treatments
  • Connexins and lens biology
  • Endoplasmic Reticulum Stress and Disease
  • Genetics, Aging, and Longevity in Model Organisms
  • Prion Diseases and Protein Misfolding

The scientist has authored multiple papers published in various journals. A sample of recent publications includes:

  • "N- and C-terminal regions of αB-crystallin and Hsp27 mediate inhibition of amyloid nucleation, fibril binding, and fibril disaggregation" (2020), Journal of Biological Chemistry
  • "An α-Cyanostilbene Derivative for the Enhanced Detection and Imaging of Amyloid Fibril Aggregates" (2020), ACS Chemical Neuroscience
  • "Real-time single-molecule observation of chaperone-assisted protein folding" (2022), Science Advances
  • "DNAJB chaperones suppress destabilised protein aggregation via a region distinct from that used to inhibit amyloidogenesis" (2021), Journal of Cell Science
  • "Proteostasis in the Male and Female Germline: A New Outlook on the Maintenance of Reproductive Health" (2021), Frontiers in Cell and Developmental Biology

Frequently, Heath Ecroyd collaborates with several researchers, including:

  • Nicholas R. Marzano
  • Antoine M. van Oijen
  • Shannon McMahon
  • Dezerae Cox
  • Bishnu P. Paudel

Publications are commonly found in a mixture of journals and platforms, with the most frequent venues being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Journal of Cell Science
  • Cell Stress and Chaperones
  • ACS Chemical Neuroscience

Best Publications

  • The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds

    Sean A. Hudson;Heath Ecroyd;Heath Ecroyd;Tak W. Kee;John A. Carver

  • Invited review: Caseins and the casein micelle: their biological functions, structures, and behavior in foods

    C Holt;John Carver;Heath Ecroyd;D.C. Thorn

  • Photosystem II: The Reaction Center of Oxygenic Photosynthesis*

    David J. Vinyard;Gennady M. Ananyev;G. Charles Dismukes

  • Post-testicular sperm environment and fertility

    Jean-Luc Gatti;Sandrine Castella;Francoise Dacheux;Heath W Ecroyd

  • Crystallin proteins and amyloid fibrils

    Heath Ecroyd;John A Carver

  • The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity

    Georg K. A. Hochberg;Heath Ecroyd;Heath Ecroyd;Cong Liu;Cong Liu;Cong Liu;Dezerae Cox;Dezerae Cox

  • Small heat-shock proteins: important players in regulating cellular proteostasis

    Teresa M. Treweek;Teresa M. Treweek;Sarah Meehan;Heath Ecroyd;Heath Ecroyd;John A. Carver

  • Walking the tightrope: proteostasis and neurodegenerative disease.

    Justin J. Yerbury;Justin J. Yerbury;Lezanne Ooi;Lezanne Ooi;Andrew Dillin;Andrew Dillin;Darren N. Saunders;Darren N. Saunders

  • Mimicking phosphorylation of alphaB-crystallin affects its chaperone activity

    Heath Ecroyd;Sarah Meehan;Joseph Horwitz;J. Andrew Aquilina

  • The growing world of small heat shock proteins: from structure to functions

    Serena Carra;Simon Alberti;Patrick A. Arrigo;Patrick A. Arrigo;Justin L. Benesch

  • Binding of the molecular chaperone αB-crystallin to Aβ amyloid fibrils inhibits fibril elongation.

    Sarah L. Shammas;Christopher A. Waudby;Shuyu Wang;Alexander K. Buell

  • Extracellular chaperones and proteostasis

    Amy R. Wyatt;Justin J. Yerbury;Heath Ecroyd;Mark R. Wilson

  • The Interaction of αB-Crystallin with Mature α-Synuclein Amyloid Fibrils Inhibits Their Elongation

    Christopher A Waudby;Christopher A Waudby;Tuomas Pj Knowles;Glyn Lee Devlin;Jeremy N Skepper

  • (−)-Epigallocatechin-3-Gallate (EGCG) Maintains κ-Casein in Its Pre-Fibrillar State without Redirecting Its Aggregation Pathway

    Sean A. Hudson;Heath Ecroyd;Francis C. Dehle;Ian F. Musgrave

  • Analysis of the mechanism by which calcium negatively regulates the tyrosine phosphorylation cascade associated with sperm capacitation

    Mark A. Baker;Louise Hetherington;Heath Ecroyd;Shaun D. Roman

  • Phosphomimics destabilize Hsp27 oligomeric assemblies and enhance chaperone activity.

    Blagojce Jovcevski;Megan A. Kelly;Anthea P. Rote;Tracey Berg

  • Endogenous Redox Activity in Mouse Spermatozoa and Its Role in Regulating the Tyrosine Phosphorylation Events Associated with Sperm Capacitation

    Heath William Ecroyd;Russell C. Jones;R. John Aitken

  • Amyloid fibril formation by bovine milk alpha s2-casein occurs under physiological conditions yet is prevented by its natural counterpart, alpha s1-casein.

    David C. Thorn;Heath Ecroyd;Margaret Sunde;Stephen Poon

  • Small Heat-shock Proteins Prevent α-Synuclein Aggregation via Transient Interactions and Their Efficacy Is Affected by the Rate of Aggregation

    Dezerae Cox;Dezerae Cox;Emily Selig;Michael D. W. Griffin;John A. Carver

  • Tyrosine Phosphorylation of HSP-90 During Mammalian Sperm Capacitation

    Heath William Ecroyd;Russell C. Jones;R. John Aitken

Frequent Co-Authors

John A. Carver
John A. Carver Australian National University
Justin J. Yerbury
Justin J. Yerbury University of Wollongong
Justin L. P. Benesch
Justin L. P. Benesch University of Oxford
Antoine M. van Oijen
Antoine M. van Oijen Illawarra Health and Medical Research Institute
Brett Nixon
Brett Nixon University of Newcastle Australia
Mark R. Wilson
Mark R. Wilson University of Wollongong
Christopher M. Dobson
Christopher M. Dobson University of Cambridge
R. John Aitken
R. John Aitken University of Newcastle Australia
Juliet A. Gerrard
Juliet A. Gerrard University of Auckland
Carol V. Robinson
Carol V. Robinson University of Oxford

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