H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Microbiology D-index 59 Citations 8,432 144 World Ranking 1197 National Ranking 71

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Immune system

His main research concerns Perforin, Virology, Granzyme, Granzyme A and Borrelia burgdorferi. Perforin is a subfield of Cytotoxic T cell that Markus M. Simon tackles. His work deals with themes such as Humoral immunity, Antibody, Immunology, Arthritis and Borrelia Burgdorferi Infection, which intersect with Virology.

His biological study spans a wide range of topics, including Natural killer cell, Granzyme B and CTL*. His Granzyme A research is multidisciplinary, incorporating perspectives in Virus, Granzyme K and Granzyme M. His Borrelia burgdorferi research includes themes of Lyme disease, Ixodes ricinus, C3-convertase and Microbiology.

His most cited work include:

  • Monoclonal antibodies specific for the outer surface protein A (OspA) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice. (225 citations)
  • Lipid A: chemical structure and biological activity. (220 citations)
  • Human and Mouse Granzyme A Induce a Proinflammatory Cytokine Response (218 citations)

What are the main themes of his work throughout his whole career to date?

Markus M. Simon focuses on Molecular biology, Virology, Borrelia burgdorferi, Cytotoxic T cell and Microbiology. His study in Molecular biology is interdisciplinary in nature, drawing from both Cell culture, T lymphocyte, Antigen and Biochemistry, Gene. His research in Virology intersects with topics in Humoral immunity, Antibody, Immunology and Borrelia.

His Borrelia burgdorferi study combines topics in areas such as Lyme disease, Factor H and Immune system. He has researched Cytotoxic T cell in several fields, including T cell and Cell biology. His Granzyme research is multidisciplinary, relying on both Granzyme B and Granzyme A.

He most often published in these fields:

  • Molecular biology (31.42%)
  • Virology (30.09%)
  • Borrelia burgdorferi (28.76%)

What were the highlights of his more recent work (between 2006-2017)?

  • Cell biology (15.93%)
  • Microbiology (22.12%)
  • Cytotoxic T cell (28.76%)

In recent papers he was focusing on the following fields of study:

Markus M. Simon mostly deals with Cell biology, Microbiology, Cytotoxic T cell, Granzyme and Virology. His Cell biology study incorporates themes from Apoptosis, Caspase, Granzyme B, GZMB and Molecular biology. Markus M. Simon combines subjects such as Virulence factor, Borrelia burgdorferi, Borrelia recurrentis and Borrelia hermsii with his study of Microbiology.

Borrelia burgdorferi is a subfield of Antibody that he investigates. His study on Granzyme is covered under Perforin. His Virology research incorporates themes from Complement factor I, Complement control protein and Innate immune system.

Between 2006 and 2017, his most popular works were:

  • Human and Mouse Granzyme A Induce a Proinflammatory Cytokine Response (218 citations)
  • Gliotoxin Is a Virulence Factor of Aspergillus fumigatus: gliP Deletion Attenuates Virulence in Mice Immunosuppressed with Hydrocortisone (176 citations)
  • Lack of the purinergic receptor P2X7 results in resistance to contact hypersensitivity (160 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Immune system

Markus M. Simon spends much of his time researching Cytotoxic T cell, Cell biology, Perforin, Granzyme and Microbiology. Many of his research projects under Cytotoxic T cell are closely connected to Secretory pathway with Secretory pathway, tying the diverse disciplines of science together. Markus M. Simon has included themes like Receptor and Granzyme B, GZMB in his Cell biology study.

His Granzyme research is under the purview of Immunology. His Microbiology study combines topics from a wide range of disciplines, such as Virulence factor and Borrelia burgdorferi. His Borrelia burgdorferi research integrates issues from Innate immune system, Factor H, Antigenic variation and Virology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Lipid A: chemical structure and biological activity.

Otto Lüderitz;Chris Galanos;Volker Lehmann;Marjatta Nurminen.
The Journal of Infectious Diseases (1973)

334 Citations

Monoclonal antibodies specific for the outer surface protein A (OspA) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice.

Ulrich E. Schaible;Michael D. Kramer;Klaus Eichmann;Manuel Modolell.
Proceedings of the National Academy of Sciences of the United States of America (1990)

319 Citations

Complement Resistance of Borrelia burgdorferi Correlates with the Expression of BbCRASP-1, a Novel Linear Plasmid-encoded Surface Protein That Interacts with Human Factor H and FHL-1 and Is Unrelated to Erp Proteins

Peter Kraiczy;Jens Hellwage;Christine Skerka;Heiko Becker.
Journal of Biological Chemistry (2004)

312 Citations

Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes

Arno Müllbacher;Paul Waring;Ron Tha Hla;Thao Tran.
Proceedings of the National Academy of Sciences of the United States of America (1999)

288 Citations

Differential recognition of structural details of bacterial lipopeptides by toll-like receptors.

Michael Morr;Osamu Takeuchi;Shizhuo Akira;Markus M. Simon.
European Journal of Immunology (2002)

285 Citations

Human and Mouse Granzyme A Induce a Proinflammatory Cytokine Response

Sunil S. Metkar;Cheikh Menaa;Julian Pardo;Julian Pardo;Baikun Wang.
Immunity (2008)

278 Citations

In Vitro– and Ex Vivo–derived Cytolytic Leukocytes from Granzyme A × B Double Knockout Mice Are Defective in Granule-mediated Apoptosis but not Lysis of Target Cells

Markus M. Simon;Michael Hausmann;Thao Tran;Klaus Ebnet.
Journal of Experimental Medicine (1997)

267 Citations

Granzyme A-deficient mice retain potent cell-mediated cytotoxicity.

K. Ebnet;M. Hausmann;F. Lehmann-Grube;A. Müllbacher.
The EMBO Journal (1995)

258 Citations

The outer surface protein A of the spirochete Borrelia burgdorferi is a plasmin(ogen) receptor

Hans Fuchs;Reinhard Wallich;Markus M. Simon;Michael D. Kramer.
Proceedings of the National Academy of Sciences of the United States of America (1994)

250 Citations

Lack of the purinergic receptor P2X7 results in resistance to contact hypersensitivity

Felix C. Weber;Philippp R. Esser;Philippp R. Esser;Tobias Müller;Jayanthi Ganesan;Jayanthi Ganesan.
Journal of Experimental Medicine (2010)

240 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Markus M. Simon

Joseph A. Trapani

Joseph A. Trapani

Peter MacCallum Cancer Centre

Publications: 89

Peter F. Zipfel

Peter F. Zipfel

Leibniz Association

Publications: 72

Erol Fikrig

Erol Fikrig

Yale University

Publications: 55

Stephen W. Barthold

Stephen W. Barthold

University of California, Davis

Publications: 53

David J. Granville

David J. Granville

University of British Columbia

Publications: 45

Phillip I. Bird

Phillip I. Bird

Discovery Institute

Publications: 42

Alan G. Barbour

Alan G. Barbour

University of California, Irvine

Publications: 42

Richard T. Marconi

Richard T. Marconi

Virginia Commonwealth University Medical Center

Publications: 36

Mark J. Smyth

Mark J. Smyth

QIMR Berghofer Medical Research Institute

Publications: 35

Reinhard Wallich

Reinhard Wallich

Heidelberg University

Publications: 34

Bettina Wilske

Bettina Wilske

Ludwig-Maximilians-Universität München

Publications: 31

Axel A. Brakhage

Axel A. Brakhage

Leibniz Association

Publications: 28

Brian Stevenson

Brian Stevenson

Swiss Institute of Bioinformatics

Publications: 28

Ulf Dittmer

Ulf Dittmer

University of Duisburg-Essen

Publications: 28

Arno Müllbacher

Arno Müllbacher

Australian National University

Publications: 27

Rolf M. Zinkernagel

Rolf M. Zinkernagel

University of Zurich

Publications: 27

Something went wrong. Please try again later.