What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Immune system
His main research concerns Perforin, Virology, Granzyme, Granzyme A and Borrelia burgdorferi.
Perforin is a subfield of Cytotoxic T cell that Markus M. Simon tackles.
His work deals with themes such as Humoral immunity, Antibody, Immunology, Arthritis and Borrelia Burgdorferi Infection, which intersect with Virology.
His biological study spans a wide range of topics, including Natural killer cell, Granzyme B and CTL*.
His Granzyme A research is multidisciplinary, incorporating perspectives in Virus, Granzyme K and Granzyme M.
His Borrelia burgdorferi research includes themes of Lyme disease, Ixodes ricinus, C3-convertase and Microbiology.
His most cited work include:
- Monoclonal antibodies specific for the outer surface protein A (OspA) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice. (225 citations)
- Lipid A: chemical structure and biological activity. (220 citations)
- Human and Mouse Granzyme A Induce a Proinflammatory Cytokine Response (218 citations)
What are the main themes of his work throughout his whole career to date?
Markus M. Simon focuses on Molecular biology, Virology, Borrelia burgdorferi, Cytotoxic T cell and Microbiology.
His study in Molecular biology is interdisciplinary in nature, drawing from both Cell culture, T lymphocyte, Antigen and Biochemistry, Gene.
His research in Virology intersects with topics in Humoral immunity, Antibody, Immunology and Borrelia.
His Borrelia burgdorferi study combines topics in areas such as Lyme disease, Factor H and Immune system.
He has researched Cytotoxic T cell in several fields, including T cell and Cell biology.
His Granzyme research is multidisciplinary, relying on both Granzyme B and Granzyme A.
He most often published in these fields:
- Molecular biology (31.42%)
- Virology (30.09%)
- Borrelia burgdorferi (28.76%)
What were the highlights of his more recent work (between 2006-2017)?
- Cell biology (15.93%)
- Microbiology (22.12%)
- Cytotoxic T cell (28.76%)
In recent papers he was focusing on the following fields of study:
Markus M. Simon mostly deals with Cell biology, Microbiology, Cytotoxic T cell, Granzyme and Virology.
His Cell biology study incorporates themes from Apoptosis, Caspase, Granzyme B, GZMB and Molecular biology.
Markus M. Simon combines subjects such as Virulence factor, Borrelia burgdorferi, Borrelia recurrentis and Borrelia hermsii with his study of Microbiology.
Borrelia burgdorferi is a subfield of Antibody that he investigates.
His study on Granzyme is covered under Perforin.
His Virology research incorporates themes from Complement factor I, Complement control protein and Innate immune system.
Between 2006 and 2017, his most popular works were:
- Human and Mouse Granzyme A Induce a Proinflammatory Cytokine Response (218 citations)
- Gliotoxin Is a Virulence Factor of Aspergillus fumigatus: gliP Deletion Attenuates Virulence in Mice Immunosuppressed with Hydrocortisone (176 citations)
- Lack of the purinergic receptor P2X7 results in resistance to contact hypersensitivity (160 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Immune system
Markus M. Simon spends much of his time researching Cytotoxic T cell, Cell biology, Perforin, Granzyme and Microbiology.
Many of his research projects under Cytotoxic T cell are closely connected to Secretory pathway with Secretory pathway, tying the diverse disciplines of science together.
Markus M. Simon has included themes like Receptor and Granzyme B, GZMB in his Cell biology study.
His Granzyme research is under the purview of Immunology.
His Microbiology study combines topics from a wide range of disciplines, such as Virulence factor and Borrelia burgdorferi.
His Borrelia burgdorferi research integrates issues from Innate immune system, Factor H, Antigenic variation and Virology.
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