2023 - Research.com Microbiology in Germany Leader Award
His main research concerns Perforin, Virology, Granzyme, Granzyme A and Borrelia burgdorferi. Perforin is a subfield of Cytotoxic T cell that Markus M. Simon tackles. His work deals with themes such as Humoral immunity, Antibody, Immunology, Arthritis and Borrelia Burgdorferi Infection, which intersect with Virology.
His biological study spans a wide range of topics, including Natural killer cell, Granzyme B and CTL*. His Granzyme A research is multidisciplinary, incorporating perspectives in Virus, Granzyme K and Granzyme M. His Borrelia burgdorferi research includes themes of Lyme disease, Ixodes ricinus, C3-convertase and Microbiology.
Markus M. Simon focuses on Molecular biology, Virology, Borrelia burgdorferi, Cytotoxic T cell and Microbiology. His study in Molecular biology is interdisciplinary in nature, drawing from both Cell culture, T lymphocyte, Antigen and Biochemistry, Gene. His research in Virology intersects with topics in Humoral immunity, Antibody, Immunology and Borrelia.
His Borrelia burgdorferi study combines topics in areas such as Lyme disease, Factor H and Immune system. He has researched Cytotoxic T cell in several fields, including T cell and Cell biology. His Granzyme research is multidisciplinary, relying on both Granzyme B and Granzyme A.
Markus M. Simon mostly deals with Cell biology, Microbiology, Cytotoxic T cell, Granzyme and Virology. His Cell biology study incorporates themes from Apoptosis, Caspase, Granzyme B, GZMB and Molecular biology. Markus M. Simon combines subjects such as Virulence factor, Borrelia burgdorferi, Borrelia recurrentis and Borrelia hermsii with his study of Microbiology.
Borrelia burgdorferi is a subfield of Antibody that he investigates. His study on Granzyme is covered under Perforin. His Virology research incorporates themes from Complement factor I, Complement control protein and Innate immune system.
Markus M. Simon spends much of his time researching Cytotoxic T cell, Cell biology, Perforin, Granzyme and Microbiology. Many of his research projects under Cytotoxic T cell are closely connected to Secretory pathway with Secretory pathway, tying the diverse disciplines of science together. Markus M. Simon has included themes like Receptor and Granzyme B, GZMB in his Cell biology study.
His Granzyme research is under the purview of Immunology. His Microbiology study combines topics from a wide range of disciplines, such as Virulence factor and Borrelia burgdorferi. His Borrelia burgdorferi research integrates issues from Innate immune system, Factor H, Antigenic variation and Virology.
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Lipid A: chemical structure and biological activity.
Otto Lüderitz;Chris Galanos;Volker Lehmann;Marjatta Nurminen.
The Journal of Infectious Diseases (1973)
Monoclonal antibodies specific for the outer surface protein A (OspA) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice.
Ulrich E. Schaible;Michael D. Kramer;Klaus Eichmann;Manuel Modolell.
Proceedings of the National Academy of Sciences of the United States of America (1990)
Complement Resistance of Borrelia burgdorferi Correlates with the Expression of BbCRASP-1, a Novel Linear Plasmid-encoded Surface Protein That Interacts with Human Factor H and FHL-1 and Is Unrelated to Erp Proteins
Peter Kraiczy;Jens Hellwage;Christine Skerka;Heiko Becker.
Journal of Biological Chemistry (2004)
Human and Mouse Granzyme A Induce a Proinflammatory Cytokine Response
Sunil S. Metkar;Cheikh Menaa;Julian Pardo;Julian Pardo;Baikun Wang.
Differential recognition of structural details of bacterial lipopeptides by toll-like receptors.
Michael Morr;Osamu Takeuchi;Shizhuo Akira;Markus M. Simon.
European Journal of Immunology (2002)
Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes
Arno Müllbacher;Paul Waring;Ron Tha Hla;Thao Tran.
Proceedings of the National Academy of Sciences of the United States of America (1999)
In Vitro– and Ex Vivo–derived Cytolytic Leukocytes from Granzyme A × B Double Knockout Mice Are Defective in Granule-mediated Apoptosis but not Lysis of Target Cells
Markus M. Simon;Michael Hausmann;Thao Tran;Klaus Ebnet.
Journal of Experimental Medicine (1997)
The outer surface protein A of the spirochete Borrelia burgdorferi is a plasmin(ogen) receptor
Hans Fuchs;Reinhard Wallich;Markus M. Simon;Michael D. Kramer.
Proceedings of the National Academy of Sciences of the United States of America (1994)
Granzyme A-deficient mice retain potent cell-mediated cytotoxicity.
Ebnet K;Hausmann M;Lehmann-Grube F;Müllbacher A.
The EMBO Journal (1995)
Gliotoxin Is a Virulence Factor of Aspergillus fumigatus: gliP Deletion Attenuates Virulence in Mice Immunosuppressed with Hydrocortisone
Janyce A. Sugui;Julian Pardo;Yun C. Chang;Kol A. Zarember.
Eukaryotic Cell (2007)
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