World's Best Scientists 2026 revealed!

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Immunology

D-Index
120
Citations
45905
World Ranking
333
National Ranking
209

Medicine

D-Index
121
Citations
46223
World Ranking
3640
National Ranking
2011

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Erol Fikrig is affiliated with Yale University in the United States and has contributed extensively to research in medicine, immunology, microbiology, and related biological sciences. Their work primarily focuses on vector-borne infectious diseases, with a significant emphasis on tick-related pathogens and immune response mechanisms.

The scientist's recent publications include studies on interactions between the Lyme disease agent Borrelia burgdorferi and ticks, as well as advancements in vaccine development targeting tick resistance and disease prevention. Notable papers include:

  • "Interactions between Borrelia burgdorferi and ticks," 2020, Nature Reviews Microbiology
  • "mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent," 2021, Science Translational Medicine
  • "Grappling with the tick microbiome," 2021, Trends in Parasitology
  • "Tick host immunity: vector immunomodulation and acquired tick resistance," 2021, Trends in Immunology
  • "Development of an mRNA-lipid nanoparticle vaccine against Lyme disease," 2023, Molecular Therapy

Their frequent coauthors include Sukanya Narasimhan, Xiao-Tian Tang, Utpal Pal, Gunjan Arora, and Alejandro Marín-López. These collaborations indicate a team-oriented approach toward studying vector-host interactions and immunological responses.

Fikrig's work appears in various scientific venues, reflecting a diverse publication record. The most common outlets are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Vaccine
  • The Journal of Infectious Diseases
  • Ticks and Tick-borne Diseases
  • mBio

Their research spans multiple fields and subfields, including medicine, immunology and microbiology, and agricultural and biological sciences. Specific subfields of study encompass public health, environmental and occupational health, parasitology, infectious diseases, insect science, and immunology.

The main topics covered in Fikrig's research are:

  • Vector-borne infectious diseases
  • Viral Infections and Vectors
  • Mosquito-borne diseases and control
  • Insect symbiosis and bacterial influences
  • Vector-Borne Animal Diseases
  • Invertebrate Immune Response Mechanisms
  • Insect and Pesticide Research

Among professional recognitions, Erol Fikrig has been named a Member of the Association of American Physicians.

Best Publications

  • The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus

    Abraham L. Brass;Abraham L. Brass;Abraham L. Brass;I-Chueh Huang;Yair Benita;Sinu P. John

  • Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

    Tian Wang;Terrence Town;Lena Alexopoulou;Lena Alexopoulou;John F Anderson

  • INTERLEUKIN (IL)-6 DIRECTS THE DIFFERENTIATION OF IL-4-PRODUCING CD4+ T CELLS

    Mercedes Rincón;Juan Anguita;Tetsuo Nakamura;Erol Fikrig

  • Vaccination against Lyme Disease with Recombinant Borrelia burgdorferi Outer-Surface Lipoprotein A with Adjuvant

    Allen C. Steere;Vijay K. Sikand;François Meurice;Dennis L. Parenti

  • Protection of mice against the Lyme disease agent by immunizing with recombinant OspA

    Erol Fikrig;Stephen W. Barthold;Fred S. Kantor;Richard A. Flavell

  • RNA interference screen for human genes associated with West Nile virus infection.

    Manoj N Krishnan;Aylwin Ng;Bindu Sukumaran;Felicia D Gilfoy

  • The Lyme disease agent exploits a tick protein to infect the mammalian host

    Nandhini Ramamoorthi;Sukanya Narasimhan;Utpal Pal;Fukai Bao

  • Age-Associated Decrease in TLR Function in Primary Human Dendritic Cells Predicts Influenza Vaccine Response

    Alexander Panda;Feng Qian;Subhasis Mohanty;David van Duin

  • Human innate immunosenescence: causes and consequences for immunity in old age.

    Alexander Panda;Alvaro Arjona;Elizabeth Sapey;Fengwei Bai

  • Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice

    Lena Alexopoulou;Venetta Thomas;Markus Schnare;Yves Lobet

  • Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine.

    A M de Silva;S R Telford;L R Brunet;S W Barthold

  • TROSPA, an Ixodes scapularis receptor for Borrelia burgdorferi

    Utpal Pal;Xin Li;Tian Wang;Ruth R. Montgomery

  • Inhibition of Th1 Differentiation by IL-6 Is Mediated by SOCS1

    Sean Diehl;Juan Anguita;Angelika Hoffmeyer;Tyler Zapton

  • STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity.

    Thomas Welte;Samuel S.M. Zhang;Tian Wang;Zhiyuan Zhang

  • The circadian clock controls toll-like receptor 9-mediated innate and adaptive immunity.

    Adam C. Silver;Alvaro Arjona;Wendy E. Walker;Wendy E. Walker;Erol Fikrig;Erol Fikrig

  • West Nile Virus: Biology, Transmission, and Human Infection

    Tonya M. Colpitts;Michael J. Conway;Ruth R. Montgomery;Erol Fikrig;Erol Fikrig

  • OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands

    Utpal Pal;Xiaofeng Yang;Manchuan Chen;Linda K. Bockenstedt

  • Gut Microbiota of the Tick Vector Ixodes scapularis Modulate Colonization of the Lyme Disease Spirochete

    Sukanya Narasimhan;Nallakkandi Rajeevan;Lei Liu;Yang O. Zhao

  • Essential Role for OspA/B in the Life Cycle of the Lyme Disease Spirochete

    Xiaofeng F. Yang;Utpal Pal;Sophie M. Alani;Erol Fikrig

  • Age-Associated Defect in Human TLR-1/2 Function

    David van Duin;Subhasis Mohanty;Venetta Thomas;Sandra Ginter

  • Tick microbiome: the force within

    Sukanya Narasimhan;Erol Fikrig;Erol Fikrig

  • Growth and migration of Borrelia burgdorferi in Ixodes ticks during blood feeding

    A M De Silva;E Fikrig

  • Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy.

    Stacey L. Demento;Stephanie C. Eisenbarth;Harald G. Foellmer;Craig Platt

Frequent Co-Authors

Richard A. Flavell
Richard A. Flavell Yale University
Stephen W. Barthold
Stephen W. Barthold University of California, Davis
Sukanya Narasimhan
Sukanya Narasimhan Yale University
Ruth R. Montgomery
Ruth R. Montgomery Yale University
John F. Anderson
John F. Anderson Connecticut Agricultural Experiment Station
Utpal Pal
Utpal Pal University of Maryland, College Park
Louis A. Magnarelli
Louis A. Magnarelli Connecticut Agricultural Experiment Station
Juan Anguita
Juan Anguita Ikerbasque
Joppe W. Hovius
Joppe W. Hovius University of Amsterdam
Sam R. Telford
Sam R. Telford Tufts University

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