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Richard A. Flavell

Richard A. Flavell

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Best Scientists
2025
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Immunology
USA
2026

D-Index & Metrics

Best Scientists

D-Index
276
Citations
288477
World Ranking
27
National Ranking
19

Immunology

D-Index
279
Citations
295732
World Ranking
2
National Ranking
1

Medicine

D-Index
279
Citations
296257
World Ranking
17
National Ranking
13

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2026 - Research.com Medicine in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Medicine in United States Leader Award
  • 2023 - Research.com Medicine in United States Leader Award
  • 2022 - Research.com Immunology in United States Leader Award
  • 2020 - Distinguished Fellows of the American Association of Immunologists (AAI)
  • 2016 - AAI Excellence in Mentoring Award, American Association of Immunologists
  • 2006 - Member of the National Academy of Medicine (NAM)
  • 2002 - Member of the National Academy of Sciences
  • 1999 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1998 - Fellow of the Royal Society, United Kingdom
  • 1988 - Member of Academia Europaea
  • 1984 - Fellow of the Royal Society, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Richard A. Flavell is affiliated with Yale University in the United States. Their research spans several interconnected fields with a strong focus on immunology and molecular biology within the medical sciences. Their work is represented extensively in areas such as Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology.

The scientist's research primarily concentrates on subfields including Immunology, Molecular Biology, Oncology, Genetics, and Epidemiology. Key topics explored in their studies encompass Immune Cell Function and Interaction, Immune Cells in Cancer, Inflammasome and Immune Disorders, T-cell and B-cell Immunology, RNA Modifications and Cancer, IL-33, ST2, and ILC Pathways, as well as Immunotherapy and Immune Responses.

Richard A. Flavell has published numerous papers with recent notable works including:

  • "Inflammasome activation in infected macrophages drives COVID-19 pathology" (2022, Nature)
  • "IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy" (2020, Nature)
  • "Potential intestinal infection and faecal-oral transmission of SARS-CoV-2" (2021, Nature Reviews Gastroenterology & Hepatology)
  • "Metabolic signaling in T cells" (2020, Cell Research)
  • "Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche" (2020, Nature)

They frequently publish in several scientific venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Proceedings of the National Academy of Sciences
  • Nature
  • UNC Libraries

The scientist collaborates regularly with a set of co-authors, among the most frequent are:

  • Esen Sefik
  • Yuval Kluger
  • Huabing Li
  • Rihao Qu
  • Samuel Huber

Richard A. Flavell's career is recognized through various honors and memberships in prestigious organizations. Awards and distinctions include:

  • Distinguished Fellows of the American Association of Immunologists (AAI), 2020
  • AAI Excellence in Mentoring Award, American Association of Immunologists, 2016
  • Member of the National Academy of Medicine (NAM), 2006
  • Member of the National Academy of Sciences, 2002
  • Fellow of the American Association for the Advancement of Science (AAAS), 1999
  • Fellow of the Royal Society, United Kingdom, twice awarded (1984 and 1998)
  • Member of Academia Europaea, 1988
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3.

    Lena Alexopoulou;Agnieszka Czopik Holt;Ruslan Medzhitov;Richard A. Flavell

  • Transforming growth factor-beta regulation of immune responses.

    Ming O. Li;Yisong Y. Wan;Shomyseh Sanjabi;Anna Karin L Robertson

  • The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells

    Wei-ping Zheng;Richard A Flavell

  • Help for cytotoxic-T-cell responses is mediated by CD40 signalling

    Sally R. M. Bennett;Sally R. M. Bennett;Francis R. Carbone;Freda Karamalis;Freda Karamalis;Richard A. Flavell

  • Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

    Jorge Alejandro Henao-Mejía;Eran Elinav;Cheng Cheng Jin;Liming Hao

  • Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

    Leo E. Otterbein;Leo E. Otterbein;Fritz H. Bach;Jawed Alam;Miguel P. Soares

  • Inflammasomes in health and disease

    Till Strowig;Jorge Henao-Mejia;Eran Elinav;Richard Flavell;Richard Flavell

  • Recognition of single-stranded RNA viruses by Toll-like receptor 7

    Jennifer M. Lund;Lena Alexopoulou;Ayuko Sato;Margaret Karow

  • Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

    Keisuke Kuida;Timothy S. Zheng;Songqing Na;Chia-Yi Kuan

  • NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

    Eran Elinav;Till Strowig;Andrew L. Kau;Jorge Henao-Mejia

  • BCL-2, BCL-XL Sequester BH3 Domain-Only Molecules Preventing BAX- and BAK-Mediated Mitochondrial Apoptosis

    Emily H.-Y.A Cheng;Michael C Wei;Solly Weiler;Richard A Flavell

  • Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms.

    Eran Elinav;Roni Nowarski;Christoph A. Thaiss;Bo Hu

  • Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway

    Cathy Tournier;Patricia M. Hess;Derek D. Yang;Jie Xu

  • Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract.

    Koichi S. Kobayashi;Mathias Chamaillard;Yasunori Ogura;Octavian Henegariu

  • MAP Kinases in the Immune Response

    Chen Dong;Roger J. Davis;Richard A. Flavell

  • CD40 and CD154 in cell-mediated immunity.

    Iqbal S. Grewal;Richard A. Flavell

  • Reduced Apoptosis and Cytochrome c-Mediated Caspase Activation in Mice Lacking Caspase 9

    Keisuke Kuida;Tarik F Haydar;Chia-Yi Kuan;Yong Gu

  • Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

    Keisuke Kuida;Judith A. Lippke;George Ku;Matthew W. Harding

  • IRAK-M is a negative regulator of toll-like receptor signaling

    Richard A. Flavell;Koichi Kobayashi;Ruslan M. Medzhitov

  • Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants.

    Stephanie C. Eisenbarth;Oscar R. Colegio;William O’Connor;Fayyaz S. Sutterwala

Frequent Co-Authors

Roger J. Davis
Roger J. Davis University of Massachusetts Chan Medical School
Erol Fikrig
Erol Fikrig Yale University
Till Strowig
Till Strowig Helmholtz Centre for Infection Research
Nicola Gagliani
Nicola Gagliani Universität Hamburg
Terrence Town
Terrence Town University of Southern California
Lena Alexopoulou
Lena Alexopoulou Centre d’Immunologie de Marseille-Luminy
Stephen W. Barthold
Stephen W. Barthold University of California, Davis
Koichi Kobayashi
Koichi Kobayashi Osaka Metropolitan University
Mercedes Rincon
Mercedes Rincon University of Vermont
Fayyaz S. Sutterwala
Fayyaz S. Sutterwala Cedars-Sinai Medical Center

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