D-Index & Metrics Best Publications

Katherine A. Fitzgerald

University of Massachusetts Medical School
United States

Immunology

USA

2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name Citations Publications World Ranking National Ranking

Immunology D-index 126 Citations 77,171 335 World Ranking 152 National Ranking 98

Medicine D-index 124 Citations 73,727 346 World Ranking 1759 National Ranking 1034

Best female scientists D-index 129 Citations 78,760 377 World Ranking 222 National Ranking 140

Research.com Recognitions

Awards & Achievements

2023 - Research.com Best Female Scientist Award

2023 - Research.com Immunology in United States Leader Award

2022 - Research.com Best Female Scientist Award

2019 - Member of the Royal Irish Academy

2014 - AAI-BD Biosciences Investigator Award, American Association of Immunologists

Overview

What is she best known for?

The fields of study she is best known for:

Gene
Enzyme
Immune system

Katherine A. Fitzgerald mostly deals with Cell biology, Inflammasome, Signal transduction, Molecular biology and Immunology. She interconnects Pyroptosis, Programmed cell death, Inflammation and Innate immune system, Immune system in the investigation of issues within Cell biology. The study incorporates disciplines such as Proinflammatory cytokine and Autophagy in addition to Inflammasome.

The concepts of her Signal transduction study are interwoven with issues in Receptor, TRIF and Caspase-11. Her Molecular biology study integrates concerns from other disciplines, such as RNA, RIG-I, Transcription factor and Gene expression. Katherine A. Fitzgerald has included themes like Endocrinology, Cathepsin B and Internal medicine in her Immunology study.

Her most cited work include:

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals (2358 citations)
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization (2114 citations)
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. (2063 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of study are Cell biology, Innate immune system, Immunology, Inflammasome and Signal transduction. Her Cell biology research is multidisciplinary, incorporating perspectives in Receptor and Toll-like receptor. Her research integrates issues of Interferon and Virology in her study of Innate immune system.

The Inflammasome study combines topics in areas such as Secretion and Microbiology. In her study, which falls under the umbrella issue of Signal transduction, RNA, Gene expression and Transcription factor is strongly linked to Molecular biology. Her studies in AIM2 integrate themes in fields like DNA and IFI16.

She most often published in these fields:

Cell biology (39.33%)
Innate immune system (28.02%)
Immunology (27.76%)

What were the highlights of her more recent work (between 2017-2021)?

Cell biology (39.33%)
Innate immune system (28.02%)
Immune system (20.05%)

In recent papers she was focusing on the following fields of study:

Katherine A. Fitzgerald mainly investigates Cell biology, Innate immune system, Immune system, Immunology and Inflammation. Her Cell biology research integrates issues from Pyroptosis, Inflammasome, Programmed cell death, Interferon and Regulator. Her Inflammasome research focuses on AIM2 in particular.

Her Innate immune system research incorporates themes from Acquired immune system, Nucleic acid, Plasmodium falciparum, Hemozoin and Regulation of gene expression. Her work on Proinflammatory cytokine, Malaria and Colitis as part of general Immunology research is frequently linked to Sting, bridging the gap between disciplines. Her Inflammation study combines topics from a wide range of disciplines, such as Receptor, Signal transduction and Cytokine.

Between 2017 and 2021, her most popular works were:

DNA sensing by the cGAS-STING pathway in health and disease. (281 citations)
Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death. (274 citations)
Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death. (274 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Peter Duewell;Hajime Kono;Katey J. Rayner;Katey J. Rayner;Cherilyn M. Sirois.
Nature (2010)

3360 Citations

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Veit Hornung;Franz G. Bauernfeind;Annett Halle;Eivind O. Samstad;Eivind O. Samstad.
Nature Immunology (2008)

2938 Citations

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

Katherine A. Fitzgerald;Sarah M. McWhirter;Kerrie L. Faia;Daniel C. Rowe.
Nature Immunology (2003)

2925 Citations

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

Kiichi Nakahira;Jeffrey Adam Haspel;Jeffrey Adam Haspel;Vijay A.K. Rathinam;Seon Jin Lee.
Nature Immunology (2011)

2529 Citations

AIM2 recognizes cytosolic dsDNA and forms a caspase-1 activating inflammasome with ASC

Veit Hornung;Veit Hornung;Andrea Ablasser;Andrea Ablasser;Marie Charrel-Dennis;Franz G. Bauernfeind;Franz G. Bauernfeind.
Nature (2009)

2415 Citations

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.

Franz G. Bauernfeind;Gabor Horvath;Andrea Stutz;Emad S. Alnemri.
Journal of Immunology (2009)

2339 Citations

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.

Annett Halle;Veit Hornung;Gabor C Petzold;Cameron R Stewart.
Nature Immunology (2008)

2321 Citations

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

Eicke Latz;Annett Schoenemeyer;Alberto Visintin;Katherine A. Fitzgerald.
Nature Immunology (2004)

1631 Citations

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

Kenichi Shimada;Timothy R. Crother;Justin Karlin;Jargalsaikhan Dagvadorj.
Immunity (2012)

1617 Citations

IFI16 is an innate immune sensor for intracellular DNA.

Leonie Unterholzner;Sinead E. Keating;Marcin Baran;Kristy A. Horan.
Nature Immunology (2010)

1609 Citations

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Frequent Co-Authors

External Links

Personal Website for Katherine A. Fitzgerald