H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 92 Citations 41,268 192 World Ranking 380 National Ranking 236
Medicine D-index 90 Citations 42,713 194 World Ranking 5833 National Ranking 3242

Research.com Recognitions

Awards & Achievements

2019 - Member of the Royal Irish Academy

2014 - AAI-BD Biosciences Investigator Award, American Association of Immunologists

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • Immune system

Her main research concerns Inflammasome, Signal transduction, Cell biology, Molecular biology and Immunology. Her Inflammasome study is focused on Inflammation in general. She interconnects Receptor, TRIF and Myeloid Differentiation Factor 88 in the investigation of issues within Signal transduction.

Her work carried out in the field of Cell biology brings together such families of science as Autophagy, Secretion, Innate immune system and Programmed cell death. Her work is dedicated to discovering how Molecular biology, Gene expression are connected with Long non-coding RNA and other disciplines. Her Immunology research is multidisciplinary, incorporating elements of Internal medicine and Endocrinology.

Her most cited work include:

  • NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals (2205 citations)
  • Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization (2032 citations)
  • IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. (1998 citations)

What are the main themes of her work throughout her whole career to date?

Katherine A. Fitzgerald mainly focuses on Cell biology, Immunology, Innate immune system, Inflammasome and Signal transduction. Her Cell biology research incorporates themes from Receptor and Toll-like receptor. Katherine A. Fitzgerald focuses mostly in the field of Innate immune system, narrowing it down to matters related to Interferon and, in some cases, IRF3 and Interferon regulatory factors.

Her Inflammasome research incorporates elements of Caspase and Microbiology. As a member of one scientific family, Katherine A. Fitzgerald mostly works in the field of Signal transduction, focusing on Molecular biology and, on occasion, RNA, Gene expression and Transcription factor. Her biological study spans a wide range of topics, including DNA and IFI16.

She most often published in these fields:

  • Cell biology (40.05%)
  • Immunology (28.01%)
  • Innate immune system (27.75%)

What were the highlights of her more recent work (between 2017-2021)?

  • Cell biology (40.05%)
  • Innate immune system (27.75%)
  • Immunology (28.01%)

In recent papers she was focusing on the following fields of study:

Katherine A. Fitzgerald mainly investigates Cell biology, Innate immune system, Immunology, Inflammation and Immune system. Katherine A. Fitzgerald has included themes like Pyroptosis, Inflammasome, Programmed cell death and Regulator in her Cell biology study. Katherine A. Fitzgerald studies Inflammasome, namely AIM2.

Her work deals with themes such as Acquired immune system, Nucleic acid, Plasmodium falciparum, Hemozoin and Regulation of gene expression, which intersect with Innate immune system. In general Immunology study, her work on Proinflammatory cytokine, Malaria and Tumor necrosis factor alpha often relates to the realm of Sting, thereby connecting several areas of interest. Her Inflammation research incorporates elements of Receptor, Signal transduction and Cytokine.

Between 2017 and 2021, her most popular works were:

  • Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death. (208 citations)
  • Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death. (208 citations)
  • DNA sensing by the cGAS-STING pathway in health and disease. (200 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Immune system

Her scientific interests lie mostly in Cell biology, Pyroptosis, Immune system, Programmed cell death and Immunity. Her work deals with themes such as Regulator, Interferon and Inflammasome, which intersect with Cell biology. Her research on Pyroptosis also deals with topics like

  • Caspase 1 together with AIM2, ATP synthase, Francisella novicida and Cytosol,
  • Cytokine, which have a strong connection to Proinflammatory cytokine and Lytic cycle.

Katherine A. Fitzgerald is studying Innate immune system, which is a component of Immune system. Her research investigates the link between Immunity and topics such as Inflammation that cross with problems in Receptor. Her biological study deals with issues like Regulation of gene expression, which deal with fields such as Signal transduction.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Peter Duewell;Hajime Kono;Katey J. Rayner;Katey J. Rayner;Cherilyn M. Sirois.
Nature (2010)

2871 Citations

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

Katherine A. Fitzgerald;Sarah M. McWhirter;Kerrie L. Faia;Daniel C. Rowe.
Nature Immunology (2003)

2703 Citations

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Veit Hornung;Franz G. Bauernfeind;Annett Halle;Eivind O. Samstad;Eivind O. Samstad.
Nature Immunology (2008)

2638 Citations

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

Kiichi Nakahira;Jeffrey Adam Haspel;Jeffrey Adam Haspel;Vijay A.K. Rathinam;Seon Jin Lee.
Nature Immunology (2011)

2171 Citations

AIM2 recognizes cytosolic dsDNA and forms a caspase-1 activating inflammasome with ASC

Veit Hornung;Veit Hornung;Andrea Ablasser;Andrea Ablasser;Marie Charrel-Dennis;Franz G. Bauernfeind;Franz G. Bauernfeind.
Nature (2009)

2168 Citations

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.

Annett Halle;Veit Hornung;Gabor C Petzold;Cameron R Stewart.
Nature Immunology (2008)

2026 Citations

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.

Franz G. Bauernfeind;Gabor Horvath;Andrea Stutz;Emad S. Alnemri.
Journal of Immunology (2009)

1914 Citations

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

Eicke Latz;Annett Schoenemeyer;Alberto Visintin;Katherine A. Fitzgerald.
Nature Immunology (2004)

1546 Citations

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

Katherine A. Fitzgerald;Eva M. Palsson-McDermott;Andrew G. Bowie;Andrew G. Bowie;Caroline A. Jefferies.
Nature (2001)

1529 Citations

LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF

Katherine A. Fitzgerald;Daniel C. Rowe;Betsy J. Barnes;Daniel R. Caffrey.
Journal of Experimental Medicine (2003)

1436 Citations

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