World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
100
Citations
67236
World Ranking
395
National Ranking
25

Overview

Veit Hornung is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research spans several interconnected fields including Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine. Major subfields of study focus on Molecular Biology, Immunology, Infectious Diseases, Epidemiology, and Genetics.

The scientist's work addresses various topics such as Inflammasome and immune disorders, interferon and immune responses, immune response and inflammation, SARS-CoV-2 and COVID-19 research, cell death mechanisms and regulation, COVID-19 clinical research studies, and heme oxygenase-1 and carbon monoxide.

Veit Hornung has published extensively, with notable papers including the following:

  • Molecular mechanisms and cellular functions of cGAS-STING signalling, 2020, Nature Reviews Molecular Cell Biology
  • Human NLRP1 is a sensor for double-stranded RNA, 2020, Science
  • Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern, 2022, Nature Medicine
  • Structural basis for sequestration and autoinhibition of cGAS by chromatin, 2020, Nature
  • CARD8 inflammasome activation triggers pyroptosis in human T cells, 2020, The EMBO Journal

Their frequent collaborators demonstrate a consistent partnership network, including Stefan Bauernfried, Oliver T. Keppler, Niklas A. Schmacke, Thomas S. Ebert, and Paul R. Wratil.

Veit Hornung's research findings are regularly published in prominent venues, highlighting a focus in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Immunity
  • Nature
  • Infection
  • Science

Best Publications

  • A mammalian microRNA expression atlas based on small RNA library sequencing.

    Pablo Landgraf;Mirabela Rusu;Robert Sheridan;Alain Sewer;Alain Sewer

  • NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

    Peter Duewell;Hajime Kono;Katey J. Rayner;Katey J. Rayner;Cherilyn M. Sirois

  • Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

    Veit Hornung;Franz G. Bauernfeind;Annett Halle;Eivind O. Samstad;Eivind O. Samstad

  • Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.

    Franz G. Bauernfeind;Gabor Horvath;Andrea Stutz;Emad S. Alnemri

  • 5'-Triphosphate RNA Is the Ligand for RIG-I

    Veit Hornung;Jana Ellegast;Sarah Kim;Krzysztof Brzózka

  • AIM2 recognizes cytosolic dsDNA and forms a caspase-1 activating inflammasome with ASC

    Veit Hornung;Veit Hornung;Andrea Ablasser;Andrea Ablasser;Marie Charrel-Dennis;Franz G. Bauernfeind;Franz G. Bauernfeind

  • The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.

    Annett Halle;Veit Hornung;Gabor C Petzold;Cameron R Stewart

  • Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides

    Veit Hornung;Simon Rothenfusser;Stefanie Britsch;Anne Krug

  • Molecular mechanisms and cellular functions of cGAS–STING signalling

    Karl-Peter Hopfner;Veit Hornung

  • cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

    Andrea Ablasser;Marion Goldeck;Taner Cavlar;Tobias Deimling

  • Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7.

    Veit Hornung;Margit Guenthner-Biller;Carole Bourquin;Andrea Ablasser

  • The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.

    Vijay A.K. Rathinam;Zhaozhao Jiang;Stephen N. Waggoner;Shrutie Sharma

  • Identification of CpG oligonucleotide sequences with high induction of IFN‐α/β in plasmacytoid dendritic cells

    Anne Krug;Simon Rothenfusser;Veit Hornung;Bernd Jahrsdörfer

  • RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate.

    Andrea Ablasser;Franz G. Bauernfeind;Gunther Hartmann;Eicke Latz

  • Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12.

    Anne Krug;Andreas Towarowski;Stefanie Britsch;Simon Rothenfusser

  • Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

    Martin Schlee;Andreas Roth;Veit Hornung;Christina Amparo Hagmann

  • Structural mechanism of cytosolic DNA sensing by cGAS

    Filiz Civril;Tobias Deimling;Carina C. de Oliveira Mann;Andrea Ablasser

  • Human Monocytes Engage an Alternative Inflammasome Pathway

    Moritz M. Gaidt;Thomas S. Ebert;Dhruv Chauhan;Tobias Schmidt

  • Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome

    Franz Bauernfeind;Eva Bartok;Anna Rieger;Luigi Franchi

  • Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP

    Andrea Ablasser;Jonathan L. Schmid-Burgk;Inga Hemmerling;Gabor L. Horvath

  • Erratum: NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals (Nature (2010) 464 (1357-1361))

    Peter Duewell;Hajime Kono;Katey J. Rayner;Cherilyn M. Sirois

Frequent Co-Authors

Gunther Hartmann
Gunther Hartmann University Hospital Bonn
Eicke Latz
Eicke Latz German Rheumatism Research Centre
Stefan Endres
Stefan Endres Ludwig-Maximilians-Universität München
Katherine A. Fitzgerald
Katherine A. Fitzgerald University of Massachusetts Chan Medical School
Karl-Peter Hopfner
Karl-Peter Hopfner Ludwig-Maximilians-Universität München
Winfried Barchet
Winfried Barchet University of Bonn
Anne Krug
Anne Krug Ludwig-Maximilians-Universität München
Oliver T. Keppler
Oliver T. Keppler Ludwig-Maximilians-Universität München
Rune Hartmann
Rune Hartmann Aarhus University
Thomas Giese
Thomas Giese Heidelberg University

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