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Rune Hartmann

Rune Hartmann

D-Index & Metrics

Microbiology

D-Index
55
Citations
13364
World Ranking
3788
National Ranking
59

Overview

Rune Hartmann is affiliated with Aarhus University in Denmark and has contributed extensively to research in the fields of Medicine and Immunology and Microbiology. Their work spans numerous subfields including Infectious Diseases, Immunology, Epidemiology, Molecular Biology, and Oncology.

The research topics covered in their publications prominently include:

  • Interferon and immune responses
  • SARS-CoV-2 and COVID-19 research
  • COVID-19 clinical research studies
  • Immune response and inflammation
  • Viral infections and vectors
  • Inflammasome and immune disorders
  • Hepatitis C virus research

Rune Hartmann's recent papers include the following:

  • Type I and III interferons disrupt lung epithelial repair during recovery from viral infection (2020, Science)
  • Inhibition of SARS-CoV-2 by type I and type III interferons (2020, Journal of Biological Chemistry)
  • COVID-19 and emerging viral infections: The case for interferon lambda (2020, The Journal of Experimental Medicine)
  • STEEP mediates STING ER exit and activation of signaling (2020, Nature Immunology)
  • Two cGAS-like receptors induce antiviral immunity in Drosophila (2021, Nature)

Frequent collaborators in Hartmann's work include:

  • Hans Henrik Gad
  • Andreas Holleufer
  • Volker Thiel
  • Ronald Dijkman
  • Ida Monrad

The most common publication venues for Hartmann's work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • PLoS Pathogens
  • The EMBO Journal
  • EBioMedicine

Best Publications

  • Double-Stranded RNA Is Produced by Positive-Strand RNA Viruses and DNA Viruses but Not in Detectable Amounts by Negative-Strand RNA Viruses

    Friedemann Weber;Valentina Wagner;Simon B. Rasmussen;Rune Hartmann

  • Type III Interferon (IFN) Induces a Type I IFN-Like Response in a Restricted Subset of Cells through Signaling Pathways Involving both the Jak-STAT Pathway and the Mitogen-Activated Protein Kinases

    Zhangle Zhou;Ole J. Hamming;Nina Ank;Søren R. Paludan

  • An important role for type III interferon (IFN-lambda/IL-28) in TLR-induced antiviral activity.

    Nina Ank;Marie B. Iversen;Christina Bartholdy;Peter Staeheli

  • Type I and III interferons disrupt lung epithelial repair during recovery from viral infection.

    Jack Major;Stefania Crotta;Miriam Llorian;Teresa M. McCabe

  • A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells.

    Joao Trindade Marques;Thalie Devosse;Die Wang;Maryam Zamanian-Daryoush

  • Guarding the frontiers: the biology of type III interferons

    Andreas Wack;Ewa Terczyńska-Dyla;Rune Hartmann

  • OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids

    Veit Hornung;Rune Hartmann;Andrea Ablasser;Karl Peter Hopfner

  • The Oligoadenylate Synthetase Family: An Ancient Protein Family with Multiple Antiviral Activities

    Helle Kristiansen;Hans Henrik Gad;Signe Eskildsen-Larsen;Signe Eskildsen-Larsen;Philippe Despres

  • Gene structure and function of the 2′-5′-oligoadenylate synthetase family

    J. Justesen;R. Hartmann;N.O. Kjeldgaard

  • Inhibition of SARS-CoV-2 by type I and type III interferons.

    Ulrike Felgenhauer;Andreas Schoen;Hans Henrik Gad;Rune Hartmann

  • cGAS is activated by DNA in a length-dependent manner.

    Stefanie Luecke;Andreas Holleufer;Maria H Christensen;Kasper L Jønsson

  • IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission

    Jonas Klinkhammer;Daniel Schnepf;Liang Ye;Marilena Schwaderlapp

  • Antiviral Activity of Human OASL Protein Is Mediated by Enhancing Signaling of the RIG-I RNA Sensor

    Jianzhong Zhu;Yugen Zhang;Arundhati Ghosh;Rolando A. Cuevas

  • The two groups of zebrafish virus-induced interferons signal via distinct receptors with specific and shared chains.

    Dina Aggad;Martine Mazel;Pierre Boudinot;Knud Erik Mogensen

  • IFNλ is a potent anti‐influenza therapeutic without the inflammatory side effects of IFNα treatment

    Sophia Davidson;Teresa M McCabe;Stefania Crotta;Hans Henrik Gad

  • Interferon-λ Is Functionally an Interferon but Structurally Related to the Interleukin-10 Family

    Hans Henrik Gad;Christoffer Dellgren;Ole J. Hamming;Susanne Vends

  • Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses

    Christian K. Holm;Stine H. Rahbek;Hans Henrik Gad;Rasmus O. Bak

  • Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses

    Ole J Hamming;Ewa Terczyńska-Dyla;Gabrielle Vieyres;Ronald Dijkman

  • HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression

    Maria H Christensen;Søren B Jensen;Juho J Miettinen;Stefanie Luecke

  • COVID-19 and emerging viral infections: The case for interferon lambda.

    Ludmila Prokunina-Olsson;Noémie Alphonse;Noémie Alphonse;Ruth E. Dickenson;Joan E. Durbin

  • Efficient Replication of the Novel Human Betacoronavirus EMC on Primary Human Epithelium Highlights Its Zoonotic Potential

    Eveline Kindler;Hulda R. Jónsdóttir;Doreen Muth;Ole J. Hamming

Frequent Co-Authors

Søren R. Paludan
Søren R. Paludan Aarhus University
Trine H. Mogensen
Trine H. Mogensen Aarhus University
Jean-Luc Imler
Jean-Luc Imler University of Strasbourg
Veit Hornung
Veit Hornung Ludwig-Maximilians-Universität München
Volker Thiel
Volker Thiel University of Bern
Peter Staeheli
Peter Staeheli University of Freiburg
Ronald Dijkman
Ronald Dijkman University of Bern
Jean-Pierre Levraud
Jean-Pierre Levraud Institut Pasteur
Andreas Wack
Andreas Wack The Francis Crick Institute
Lars Østergaard
Lars Østergaard Aarhus University Hospital

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