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Biology and Biochemistry

D-Index
63
Citations
17996
World Ranking
10051
National Ranking
359

Overview

Jean-Luc Imler is affiliated with the University of Strasbourg in France. Their research spans multiple fields, primarily focusing on Medicine and Immunology and Microbiology, with notable subfields including Immunology, Infectious Diseases, Public Health, Environmental and Occupational Health, Molecular Biology, and Insect Science.

The scientist investigates several main topics, such as:

  • interferon and immune responses
  • Viral Infections and Vectors
  • Mosquito-borne diseases and control
  • Invertebrate Immune Response Mechanisms
  • Insect symbiosis and bacterial influences
  • Immune Cell Function and Interaction
  • Plant Virus Research Studies

Jean-Luc Imler has contributed to multiple recent research papers, including:

  • "cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila" (2021, Nature)
  • "Two cGAS-like receptors induce antiviral immunity in Drosophila" (2021, Nature)
  • "Mosquito vector competence for dengue is modulated by insect-specific viruses" (2023, Nature Microbiology)
  • "2'3'-cGAMP triggers a STING- and NF-κB-dependent broad antiviral response in Drosophila" (2020, Science Signaling)
  • "The virus-induced cyclic dinucleotide 2'3'-c-di-GMP mediates STING-dependent antiviral immunity in Drosophila" (2023, Immunity)

Their frequent co-authors include Hua Cai, João T. Marques, Carine Meignin, Ziming Wei, and Roenick Proveti Olmo.

Jean-Luc Imler's publications often appear in venues such as:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Cell Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Comptes Rendus Biologies

Best Publications

  • Insights into social insects from the genome of the honeybee Apis mellifera

    George M. Weinstock;Gene E. Robinson;Richard A. Gibbs;Kim C. Worley

  • Immune pathways and defence mechanisms in honey bees Apis mellifera

    J D Evans;K Aronstein;Y P Chen;C Hetru

  • The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections

    Dominique Ferrandon;Jean-Luc Imler;Charles Hetru;Jules A. Hoffmann

  • The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila.

    Catherine Dostert;Emmanuelle Jouanguy;Emmanuelle Jouanguy;Phil Irving;Laurent Troxler

  • Tissue-Specific Inducible Expression of Antimicrobial Peptide Genes in Drosophila Surface Epithelia

    Phoebe Tzou;Serge Ohresser;Dominique Ferrandon;Maria Capovilla

  • Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila

    Delphine Galiana-Arnoux;Catherine Dostert;Anette Schneemann;Jules A Hoffmann

  • Toll receptors in innate immunity

    Jean-Luc Imler;Jules A. Hoffmann

  • Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling

    Alexander N.R. Weber;Servane Tauszig-Delamasure;Jules A. Hoffmann;Eric Lelièvre

  • Toll-related receptors and the control of antimicrobial peptide expression in Drosophila.

    Servane Tauszig;Emmanuelle Jouanguy;Jules A. Hoffmann;Jean-Luc Imler

  • Antimicrobial peptides in Drosophila: structures, activities and gene regulation.

    Jean-Luc Imler;Philippe Bulet

  • The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila.

    Safia Deddouche;Nicolas Matt;Aidan Budd;Stefanie Mueller

  • Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections.

    Servane Tauszig-Delamasure;Hana Bilak;Maria Capovilla;Jules A. Hoffmann

  • The 5' flanking region of the pS2 gene contains a complex enhancer region responsive to oestrogens, epidermal growth factor, a tumour promoter (TPA), the c-Ha-ras oncoprotein and the c-jun protein.

    A. M. Nunez;M. Berry;J. L. Imler;P. Chambon

  • Signaling mechanisms in the antimicrobial host defense of Drosophila.

    Jean-Luc Imler;Jules A Hoffmann

  • Broad RNA Interference–Mediated Antiviral Immunity and Virus-Specific Inducible Responses in Drosophila

    Cordula Kemp;Stefanie Mueller;Akira Goto;Vincent Barbier

  • Genetic analysis of resistance to viral infection

    Bruce Beutler;Celine Eidenschenk;Karine Crozat;Jean Luc Imler

  • A Harvey-ras responsive transcription element is also responsive to a tumour-promoter and to serum.

    J L Imler;C Schatz;C Wasylyk;B Chatton

  • Antiviral immunity in drosophila

    Cordula Kemp;Jean-Luc Imler;Jean-Luc Imler

  • Biology of Toll receptors: lessons from insects and mammals

    Jean-Luc Imler;Liangbiao Zheng

  • Lung Gene Therapy: In Vivo Adenovirus-Mediated Gene Transfer to Rhesus Monkey Airway Epithelium

    Abraham Bout;Michel Perricaudet;Gary Baskin;Jean-Luc Imler

Frequent Co-Authors

Jules A. Hoffmann
Jules A. Hoffmann University of Strasbourg
Charles Hetru
Charles Hetru Institute for Molecular and Cellular Biology
Bohdan Wasylyk
Bohdan Wasylyk Institute of Genetics and Molecular and Cellular Biology
Emmanuelle Jouanguy
Emmanuelle Jouanguy Necker-Enfants Malades Hospital
Jean-Marc Reichhart
Jean-Marc Reichhart University of Strasbourg
Lauriane Kuhn
Lauriane Kuhn Centre national de la recherche scientifique, CNRS
Bruce Beutler
Bruce Beutler The University of Texas Southwestern Medical Center
Erna Geessien Kroon
Erna Geessien Kroon Universidade Federal de Minas Gerais
Philippe Bulet
Philippe Bulet Grenoble Alpes University
Michael B. Eisen
Michael B. Eisen University of California, Berkeley

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