World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
97
Citations
45418
World Ranking
806
National Ranking
20

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Bruno Lemaitre is affiliated with the École Polytechnique Fédérale de Lausanne in Switzerland. Their research primarily spans Agricultural and Biological Sciences and Immunology and Microbiology, with specific focus on areas such as Insect Science, Immunology, Cellular and Molecular Neuroscience, Microbiology, and Molecular Biology.

The scientist's work centers on the study of insect symbiosis and bacterial influences, invertebrate immune response mechanisms, and insect utilization and effects. Other notable research topics include neurobiology and insect physiology, insect-plant interactions and control, antimicrobial peptides and activities, and insect behavior and control techniques.

Lemaitre's publication record includes papers in several established venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Immunity
  • Cell Reports
  • Journal of Clinical Investigation

Recent research contributions cover diverse aspects of immunity and insect biology. Selected recent papers are:

  • Drosophila Antimicrobial Peptides and Lysozymes Regulate Gut Microbiota Composition and Abundance, 2021, mBio
  • Iron sequestration by transferrin 1 mediates nutritional immunity in Drosophila melanogaster, 2020, Proceedings of the National Academy of Sciences
  • The conceptual foundations of innate immunity: Taking stock 30 years later, 2024, Immunity
  • Ecology-relevant bacteria drive the evolution of host antimicrobial peptides in Drosophila, 2023, Science
  • Renal Purge of Hemolymphatic Lipids Prevents the Accumulation of ROS-Induced Inflammatory Oxidized Lipids and Protects Drosophila from Tissue Damage, 2020, Immunity

Frequent collaborators include Mark A. Hanson, Florent Masson, Samuel Rommelaere, Fanny Schüpfer, and Shu Kondo. These partnerships reflect recurring coauthorship across numerous publications.

In addition to journal articles, Bruno Lemaitre has contributed to book publications, including "The Drosophila immunity handbook," published by EPFL Press eBooks in 2024.

The scientist is recognized as a member of the European Molecular Biology Organization (EMBO), indicating membership in a major scientific society.

Best Publications

  • The Host Defense of Drosophila melanogaster

    Bruno Lemaitre;Jules Hoffmann

  • Drosophila host defense: Differential induction of antimicrobial peptide genes after infection by various classes of microorganisms

    Bruno Lemaitre;Jean-Marc Reichhart;Jules A. Hoffmann

  • The Toll and Imd pathways are the major regulators of the immune response in Drosophila

    Ennio De Gregorio;Paul T. Spellman;Phoebe Tzou;Gerald M. Rubin

  • Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation

    Nicolas Buchon;Nichole A. Broderick;Mickael Poidevin;Sylvain Pradervand

  • Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays.

    Ennio De Gregorio;Paul T. Spellman;Gerald M. Rubin;Bruno Lemaitre

  • Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

    Nicolas Buchon;Nichole A. Broderick;Sveta Chakrabarti;Bruno Lemaitre

  • A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense

    Bruno Lemaitre;Elisabeth Kromer-Metzger;Lydia Michaut;Emmanuelle Nicolas

  • The Drosophila immune system detects bacteria through specific peptidoglycan recognition.

    François Leulier;Claudine Parquet;Sebastien Pili-Floury;Ji-Hwan Ryu

  • Tissue-Specific Inducible Expression of Antimicrobial Peptide Genes in Drosophila Surface Epithelia

    Phoebe Tzou;Serge Ohresser;Dominique Ferrandon;Maria Capovilla

  • Toll-like receptors — taking an evolutionary approach

    François Leulier;Bruno Lemaitre

  • The Digestive Tract of Drosophila melanogaster

    Bruno Lemaitre;Irene Miguel-Aliaga

  • The Drosophila Amidase PGRP-LB Modulates the Immune Response to Bacterial Infection

    Anna Zaidman-Rémy;Mireille Hervé;Mickael Poidevin;Sébastien Pili-Floury

  • Gut homeostasis in a microbial world: insights from Drosophila melanogaster

    Nicolas Buchon;Nichole A. Broderick;Bruno Lemaitre

  • Drosophila host defense after oral infection by an entomopathogenic Pseudomonas species.

    Nicolas Vodovar;Marisa Vinals;Peter Liehl;Alan Basset

  • The Drosophila caspase Dredd is required to resist Gram-negative bacterial infection

    François Leulier;Antony Rodriguez;Ranjiv S Khush;John M Abrams

  • How Drosophila combats microbial infection: a model to study innate immunity and host-pathogen interactions.

    Phoebe Tzou;Ennio De Gregorio;Bruno Lemaitre

  • A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway

    D. Ferrandon;A.C. Jung;M.‐C. Criqui;B. Lemaitre

  • Microbiota-Induced Changes in Drosophila melanogaster Host Gene Expression and Gut Morphology

    Nichole A. Broderick;Nicolas Buchon;Bruno Lemaitre

  • Gram-negative Bacteria-binding Protein, a Pattern Recognition Receptor for Lipopolysaccharide and β-1,3-Glucan That Mediates the Signaling for the Induction of Innate Immune Genes in Drosophila melanogaster Cells

    Yong-Sik Kim;Ji-Hwan Ryu;Sung-Jun Han;Kun-Ho Choi

  • Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection

    Nicolas Buchon;Nichole A Broderick;Takayuki Kuraishi;Bruno Lemaitre

  • The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response

    Alan Basset;Ranjiv S. Khush;Anne Braun;Louis Gardan

Frequent Co-Authors

Jules A. Hoffmann
Jules A. Hoffmann University of Strasbourg
Jean-Marc Reichhart
Jean-Marc Reichhart University of Strasbourg
Ryu Ueda
Ryu Ueda National Institute of Genetics
Dominique Mengin-Lecreulx
Dominique Mengin-Lecreulx University of Paris-Saclay
Ennio De Gregorio
Ennio De Gregorio Novartis (Switzerland)
Philippe Bulet
Philippe Bulet Grenoble Alpes University
Pascal Meier
Pascal Meier Institute of Cancer Research
Paul T. Spellman
Paul T. Spellman Oregon Health & Science University
Philippe Georgel
Philippe Georgel University of Strasbourg
Bart Deplancke
Bart Deplancke École Polytechnique Fédérale de Lausanne

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