Philippe Georgel

Overview

Best Publications

• Identification of Lps2 as a key transducer of MyD88-independent TIR signalling.

  K. Hoebe;X. Du;P. Georgel;E. Janssen

  1558
  Citations

• Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection

  Koichi Tabeta;Philippe Georgel;Edith Janssen;Xin Du

  1272
  Citations

• CD36 is a sensor of diacylglycerides

  Kasper Hoebe;Philippe Georgel;Sophie Rutschmann;Xin Du

  1068
  Citations

• Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

  Bruce Beutler;Zhengfan Jiang;Philippe Georgel;Karine Crozat

  970
  Citations

• CD14 is required for MyD88-independent LPS signaling

  Zhengfan Jiang;Philippe Georgel;Xin Du;Louis Shamel

  862
  Citations

• The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.

  Koichi Tabeta;Kasper Hoebe;Edith M. Janssen;Xin Du

  795
  Citations

• A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense

  Bruno Lemaitre;Elisabeth Kromer-Metzger;Lydia Michaut;Emmanuelle Nicolas

  753
  Citations

• Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis.

  Philippe Georgel;Silvia Naitza;Christine Kappler;Dominique Ferrandon

  519
  Citations

• Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression

  Motoyuki Otsuka;Qing Jing;Philippe Georgel;Liguo New

  454
  Citations

• Chromatin Compaction by Human MeCP2 ASSEMBLY OF NOVEL SECONDARY CHROMATIN STRUCTURES IN THE ABSENCE OF DNA METHYLATION

  Philippe T. Georgel;Philippe T. Georgel;Rachel A. Horowitz-Scherer;Nick Adkins;Christopher L. Woodcock

  388
  Citations

• Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila.

  B. Lemaitre;M. Meister;S. Govind;P. Georgel

  331
  Citations

• Protein kinase D at the Golgi controls NLRP3 inflammasome activation.

  Zhirong Zhang;Gergö Meszaros;Wan-ting He;Yanfang Xu

  292
  Citations

• Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway.

  Philippe Georgel;Zhengfan Jiang;Stefan Kunz;Edith Janssen

  267
  Citations

• The non-conventional MHC class I MR1 molecule controls infection by Klebsiella pneumoniae in mice.

  Philippe Georgel;Mirjana Radosavljevic;Cécile Macquin;Seiamak Bahram

  226
  Citations

• A Toll-Like Receptor 2-Responsive Lipid Effector Pathway Protects Mammals against Skin Infections with Gram-Positive Bacteria

  Philippe Georgel;Karine Crozat;Xavier Lauth;Evgenia Makrantonaki

  226
  Citations

• R-form LPS, the master key to the activation of TLR4/MD-2-positive cells

  Michael Huber;Christoph Kalis;Simone Keck;Zhengfan Jiang

  218
  Citations

• HDAC1 Acetylation Is Linked to Progressive Modulation of Steroid Receptor-Induced Gene Transcription

  Yi Qiu;Yingming Zhao;Matthias Becker;Sam John

  215
  Citations

• Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells

  Amanda L. Blasius;Carrie N. Arnold;Philippe Georgel;Philippe Georgel;Sophie Rutschmann;Sophie Rutschmann

  209
  Citations

• TLR2 Expression Is Regulated by MicroRNA miR-19 in Rheumatoid Fibroblast-like Synoviocytes

  Lucas Philippe;Ghada Alsaleh;Guillaume Suffert;Alain Meyer

  200
  Citations

• The Drosophila Immune Defense against Gram-Negative Infection Requires the Death Protein dFADD

  Silvia Naitza;Carine Rossé;Christine Kappler;Philippe Georgel

  198
  Citations