World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
19269
World Ranking
16439
National Ranking
6801

Overview

Kasper Hoebe is affiliated with Johnson & Johnson in the United States. Their research spans several fields, primarily focusing on Immunology and Microbiology, Medicine, and Biochemistry, Genetics, and Molecular Biology. The subfields of study related to their work include Immunology, Molecular Biology, Epidemiology, Cancer Research, and Oncology.

Their scientific output includes publications in notable venues such as:

  • Journal for ImmunoTherapy of Cancer
  • Proceedings of the National Academy of Sciences
  • The Journal of Experimental Medicine
  • PLoS Pathogens
  • ImmunoHorizons

Key research topics addressed by Hoebe cover a range of areas including:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Cancer-related molecular mechanisms research
  • RNA Research and Splicing
  • Immune Response and Inflammation
  • Reproductive System and Pregnancy
  • Immune cells in cancer

Among their recent scientific papers are:

  • "CD244 represents a new therapeutic target in head and neck squamous cell carcinoma," published in 2020 in the Journal for ImmunoTherapy of Cancer
  • "The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2," 2022, Proceedings of the National Academy of Sciences
  • "GIMAP5 maintains liver endothelial cell homeostasis and prevents portal hypertension," 2021, The Journal of Experimental Medicine
  • "Resolution of herpes simplex virus reactivation in vivo results in neuronal destruction," 2020, PLoS Pathogens
  • "Type I IFN Drives Experimental Systemic Lupus Erythematosus by Distinct Mechanisms in CD4 T Cells and B Cells," 2020, ImmunoHorizons

Frequent collaborators in their research include Kristin Lampe, Tim Vierbuchen, Katherine A. Fitzgerald, Jazib Uddin, and Simone Vanoni, each with multiple coauthored works reflecting ongoing collaborative efforts in the field.

Best Publications

  • Identification of Lps2 as a key transducer of MyD88-independent TIR signalling.

    K. Hoebe;X. Du;P. Georgel;E. Janssen

  • Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections

    Jochen Mattner;Kristin L. DeBord;Nahed Ismail;Randal D. Goff

  • Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection

    Koichi Tabeta;Philippe Georgel;Edith Janssen;Xin Du

  • The interface between innate and adaptive immunity.

    Kasper Hoebe;Edith Janssen;Bruce Beutler

  • CD36 is a sensor of diacylglycerides

    Kasper Hoebe;Philippe Georgel;Sophie Rutschmann;Xin Du

  • Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

    Bruce Beutler;Zhengfan Jiang;Philippe Georgel;Karine Crozat

  • Herpes simplex virus encephalitis in human UNC-93B deficiency.

    Armanda Casrouge;Shen Ying Zhang;Shen Ying Zhang;Céline Eidenschenk;Emmanuelle Jouanguy;Emmanuelle Jouanguy

  • How we detect microbes and respond to them: the Toll-like receptors and their transducers.

    B. Beutler;K. Hoebe;X. Du;R. J. Ulevitch

  • The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.

    Koichi Tabeta;Kasper Hoebe;Edith M. Janssen;Xin Du

  • Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria.

    Yuki Kinjo;Emmanuel Tupin;Douglass Wu;Masakazu Fujio

  • Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy

    Bernice Lo;Kejian Zhang;Wei Lu;Lixin Zheng

  • Adjuvant-Enhanced Antibody Responses in the Absence of Toll-Like Receptor Signaling

    Amanda L. Gavin;Kasper Hoebe;Bao Duong;Takayuki Ota

  • TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity

    Roberto Baccala;Kasper Hoebe;Dwight H. Kono;Bruce A Beutler

  • Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways

    Kasper Hoebe;Edith M. Janssen;Sung O. Kim;Lena Alexopoulou

  • The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

    Melanie M. Brinkmann;Eric Spooner;Kasper Hoebe;Bruce Beutler

  • Cutting Edge: Priming of NK Cells by IL-18

    Julie Chaix;Marlowe S. Tessmer;Kasper Hoebe;Nicolas Fuséri

  • Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway.

    Philippe Georgel;Zhengfan Jiang;Stefan Kunz;Edith Janssen

  • A Toll-Like Receptor 2-Responsive Lipid Effector Pathway Protects Mammals against Skin Infections with Gram-Positive Bacteria

    Philippe Georgel;Karine Crozat;Xavier Lauth;Evgenia Makrantonaki

  • The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung.

    Catharina W. Wieland;Sandrine Florquin;Nico A. Maris;Kasper Hoebe

  • Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis

    Karine Crozat;Kasper Hoebe;Sophie Ugolini;Sophie Ugolini;Nancy A. Hong

Frequent Co-Authors

Bruce Beutler
Bruce Beutler The University of Texas Southwestern Medical Center
Philippe Georgel
Philippe Georgel University of Strasbourg
Karine Crozat
Karine Crozat Aix-Marseille University
David A. Hildeman
David A. Hildeman Cincinnati Children's Hospital Medical Center
Zhengfan Jiang
Zhengfan Jiang Peking University
Jörg Köhl
Jörg Köhl University of Lübeck
Eric Vivier
Eric Vivier Aix-Marseille University
Simon P. Hogan
Simon P. Hogan Cincinnati Children's Hospital Medical Center
Argyrios N. Theofilopoulos
Argyrios N. Theofilopoulos Scripps Research Institute
H. Leighton Grimes
H. Leighton Grimes Cincinnati Children's Hospital Medical Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Kasper Hoebe

Trending Scientists

Recently Published Articles