Signal transduction, Innate immune system, Receptor, Immunology and Molecular biology are his primary areas of study. His study looks at the intersection of Signal transduction and topics like Toll-like receptor with Nonsense mutation and TLR2. His Innate immune system research integrates issues from Lipopolysaccharide, Cellular immunity, Antigen, Natural killer cell and Immunity.
The study incorporates disciplines such as Zymosan and Interferon in addition to Receptor. His Immune system, Autoimmunity, Immune receptor and Immunodeficiency study, which is part of a larger body of work in Immunology, is frequently linked to Abatacept, bridging the gap between disciplines. His studies deal with areas such as Signal transducing adaptor protein, TRIF, Endoplasmic reticulum, TLR3 and UNC93B1 as well as Molecular biology.
Kasper Hoebe focuses on Immunology, Cell biology, Immune system, Innate immune system and Receptor. His Immunology research incorporates themes from Cytotoxic T cell and Cellular differentiation. Kasper Hoebe has included themes like T cell, Interleukin 21, IL-2 receptor, Interferon and Antigen in his Cell biology study.
His Innate immune system research is multidisciplinary, incorporating perspectives in Positional cloning, Signal transduction, CD14 and Microbiology. His Signal transduction study combines topics from a wide range of disciplines, such as Toll-like receptor and TRIF. His research integrates issues of Cell, Downregulation and upregulation and Effector in his study of Receptor.
His primary scientific interests are in Immune system, T cell, Inflammation, Mutation and Cancer research. His Immune system study is associated with Immunology. His research in T cell intersects with topics in Acquired immune system, Molecular biology, Dendritic cell and Programmed cell death.
His Inflammation research includes themes of Cellular differentiation, Innate lymphoid cell, FOXP3 and Lymphocyte homeostasis. His Mutation study integrates concerns from other disciplines, such as Lymphocyte proliferation, Lymphocyte, Autoimmunity and Cell biology. His studies in Cell integrate themes in fields like Tumor microenvironment, Cancer, Function, Receptor and Effector.
His primary areas of study are Cancer research, SIGNALING LYMPHOCYTE ACTIVATION MOLECULE, Effector, Receptor and Function. Kasper Hoebe integrates Cancer research and Steatohepatitis in his research. Steatohepatitis is connected with Nonalcoholic fatty liver disease, Cirrhosis, Beta oxidation, Inflammation and ACOX1 in his research.
His Nonalcoholic fatty liver disease investigation overlaps with other disciplines such as Pathogenesis and Steatosis. His work in SIGNALING LYMPHOCYTE ACTIVATION MOLECULE incorporates the disciplines of Immune system, Tumor microenvironment, Cancer and Cell.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling.
K. Hoebe;X. Du;P. Georgel;E. Janssen.
Nature (2003)
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
Koichi Tabeta;Philippe Georgel;Edith Janssen;Xin Du.
Proceedings of the National Academy of Sciences of the United States of America (2004)
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
Jochen Mattner;Kristin L. DeBord;Nahed Ismail;Randal D. Goff.
Nature (2005)
The interface between innate and adaptive immunity.
Kasper Hoebe;Edith Janssen;Bruce Beutler.
Nature Immunology (2004)
CD36 is a sensor of diacylglycerides
Kasper Hoebe;Philippe Georgel;Sophie Rutschmann;Xin Du.
Nature (2005)
Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large
Bruce Beutler;Zhengfan Jiang;Philippe Georgel;Karine Crozat.
Annual Review of Immunology (2006)
How we detect microbes and respond to them: the Toll-like receptors and their transducers.
B. Beutler;K. Hoebe;X. Du;R. J. Ulevitch.
Journal of Leukocyte Biology (2003)
Herpes simplex virus encephalitis in human UNC-93B deficiency.
Armanda Casrouge;Shen Ying Zhang;Shen Ying Zhang;Céline Eidenschenk;Emmanuelle Jouanguy;Emmanuelle Jouanguy.
Science (2006)
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.
Koichi Tabeta;Kasper Hoebe;Edith M. Janssen;Xin Du.
Nature Immunology (2006)
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria.
Yuki Kinjo;Emmanuel Tupin;Douglass Wu;Masakazu Fujio.
Nature Immunology (2006)
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