What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Cytokine
Winfried Barchet mainly investigates Interferon, Cell biology, Virology, Molecular biology and RNA.
His work in the fields of Interferon, such as Alpha interferon, intersects with other areas such as Toll-Like Receptor 9 and TLR9.
His Cell biology research is multidisciplinary, incorporating elements of NK-92, Interleukin 21 and Granzyme B, Granzyme A.
His work in Virology is not limited to one particular discipline; it also encompasses Innate immune system.
Winfried Barchet combines subjects such as Virus and Herpes simplex virus with his study of Innate immune system.
His studies in Molecular biology integrate themes in fields like Non-coding RNA, 2'-O-methylation, Gene expression, Five-prime cap and RNA-binding protein.
His most cited work include:
- Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus (977 citations)
- Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3 (910 citations)
- Human T Regulatory Cells Can Use the Perforin Pathway to Cause Autologous Target Cell Death (796 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Immunology, Cell biology, Innate immune system, Interferon and Immune system.
The study incorporates disciplines such as Cytokine, Antigen-presenting cell, Interleukin 21, Dendritic cell and Endothelium in addition to Cell biology.
His research in Innate immune system focuses on subjects like RNA, which are connected to Molecular biology.
Interferon is the subject of his research, which falls under Virology.
His Virology research integrates issues from RIG-I and Microbiology.
His work deals with themes such as Respiratory burst, Receptor, Nucleic acid and DNA, which intersect with Immune system.
He most often published in these fields:
- Immunology (34.88%)
- Cell biology (34.88%)
- Innate immune system (32.56%)
What were the highlights of his more recent work (between 2014-2020)?
- Cell biology (34.88%)
- Innate immune system (32.56%)
- Interferon (29.07%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Cell biology, Innate immune system, Interferon, Immune system and Molecular biology.
His research in Cell biology intersects with topics in Cytokine, TLR7, Dendritic cell, Chemokine and Endogeny.
His Innate immune system study combines topics from a wide range of disciplines, such as RNA and Immunity.
His Interferon study contributes to a more complete understanding of Virology.
His study in Virology is interdisciplinary in nature, drawing from both RIG-I and Nucleotide.
His Immune system study is associated with Immunology.
Between 2014 and 2020, his most popular works were:
- CD8+ T Cells Orchestrate pDC-XCR1+ Dendritic Cell Spatial and Functional Cooperativity to Optimize Priming. (132 citations)
- Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA (124 citations)
- A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2′O-Methylated Self RNA (122 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Immune system
- Cytokine
Winfried Barchet spends much of his time researching Immunology, Interferon, Nucleic acid, Immune system and Cytotoxic T cell.
He works in the field of Interferon, focusing on Alpha interferon in particular.
Within one scientific family, Winfried Barchet focuses on topics pertaining to Pattern recognition receptor under Nucleic acid, and may sometimes address concerns connected to Cancer.
His work carried out in the field of Immune system brings together such families of science as Receptor and Drug discovery.
His Cytotoxic T cell research includes themes of Cancer cell, CD8, Immunogenicity, Immunotherapy and Effector.
Cellular immunity and Cell biology are frequently intertwined in his study.
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