World's Best Scientists 2026 revealed!
Winfried Barchet

Winfried Barchet

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
18961
World Ranking
15907
National Ranking
1118

Overview

Winfried Barchet is a researcher affiliated with the University of Bonn in Germany. Their work primarily focuses on immunology and microbiology, with an emphasis on immune response mechanisms and interactions at the molecular level.

The scientist's main fields of study include:

  • Immunology and Microbiology

Within these fields, their research spans several subfields:

  • Immunology
  • Microbiology
  • Molecular Biology
  • Public Health, Environmental and Occupational Health
  • Parasitology

Barchet's research topics cover a range of immunological processes and responses, including:

  • Immune Response and Inflammation
  • Interferon and Immune Responses
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • Antimicrobial Peptides and Activities
  • Malaria Research and Control
  • Vaccines and Immunoinformatics Approaches

The researcher has contributed to several peer-reviewed papers, notable among which are:

  • "Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2" (2020, Immunity)
  • "A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice" (2020, Cell Host & Microbe)
  • "Absence of cGAS-mediated type I IFN responses in HIV-1-infected T cells" (2020, Proceedings of the National Academy of Sciences)
  • "Complexing CpG adjuvants with cationic liposomes enhances vaccine-induced formation of liver TRM cells" (2023, Vaccine)
  • "Immune Profiling of Vulvar Squamous Cell Cancer Discovers a Macrophage-rich Subtype Associated with Poor Prognosis" (2024, Cancer Research Communications)

These publications reflect engagement with both fundamental and applied aspects of immunology, including host-pathogen interactions and vaccine development strategies.

Barchet frequently collaborates with several researchers, including:

  • Thomas Zillinger
  • Gunther Hartmann
  • Thomas Ostendorf
  • Saskia Schmitz
  • Samira Marx

Their work appears in multiple scientific venues, indicating a cross-disciplinary approach to immunological research. Frequent publication venues include:

  • Immunity
  • Cell Host & Microbe
  • Proceedings of the National Academy of Sciences
  • Vaccine
  • Cancer Research Communications

Best Publications

  • Human T Regulatory Cells Can Use the Perforin Pathway to Cause Autologous Target Cell Death

    William J. Grossman;James W. Verbsky;Winfried Barchet;Marco Colonna

  • Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

    Leonid Gitlin;Winfried Barchet;Susan Gilfillan;Marina Cella

  • Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

    Thirumala Devi Kanneganti;Nesrin Özören;Mathilde Body-Malapel;Amal Amer

  • Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

    Pu Gao;Manuel Ascano;Yang Wu;Winfried Barchet

  • TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function.

    Anne Krug;Anthony R French;Winfried Barchet;Jens A.A Fischer

  • Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

    Martin Schlee;Andreas Roth;Veit Hornung;Christina Amparo Hagmann

  • Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.

    Anne Krug;Gary D. Luker;Gary D. Luker;Winfried Barchet;Winfried Barchet;David A. Leib;David A. Leib

  • Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5

    Roland Züst;Roland Züst;Luisa Cervantes-Barragan;Matthias Habjan;Reinhard Maier

  • Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1|[beta]| production

    Hendrik Poeck;Michael Bscheider;Olaf Gross;Olaf Gross;Katrin Finger

  • Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates

    Delphine Goubau;Martin Schlee;Safia Deddouche;Andrea J. Pruijssers

  • Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA.

    Pu Gao;Manuel Ascano;Thomas Zillinger;Weiyi Wang

  • Oxidative Damage of DNA Confers Resistance to Cytosolic Nuclease TREX1 Degradation and Potentiates STING-Dependent Immune Sensing

    Nadine Gehrke;Christina Mertens;Thomas Zillinger;Jörg Wenzel

  • Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

    Peter Liehl;Vanessa Zuzarte-Luís;Jennie Chan;Thomas Zillinger

  • Virus-induced Interferon α Production by a Dendritic Cell Subset in the Absence of Feedback Signaling In Vivo

    Winfried Barchet;Marina Cella;Bernhard Odermatt;Carine Asselin-Paturel

  • CD8+ T Cells Orchestrate pDC-XCR1+ Dendritic Cell Spatial and Functional Cooperativity to Optimize Priming.

    Anna Brewitz;Sarah Eickhoff;Sabrina Dähling;Thomas Quast

  • Targeted Disruption of LIGHT Causes Defects in Costimulatory T Cell Activation and Reveals Cooperation with Lymphotoxin β in Mesenteric Lymph Node Genesis

    Stefanie Scheu;Judith Alferink;Tobias Pötzel;Winfried Barchet

  • A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2′O-Methylated Self RNA

    Christine Schuberth-Wagner;Janos Ludwig;Ann Kristin Bruder;Anna-Maria Herzner

  • PKR and RNase L contribute to protection against lethal West Nile Virus infection by controlling early viral spread in the periphery and replication in neurons.

    Melanie A Samuel;Kevin Whitby;Kevin Whitby;Brian C Keller;Anantha Marri

  • Plasmacytoid dendritic cells--virus experts of innate immunity.

    Winfried Barchet;Marina Cella;Marco Colonna

  • Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA

    Anna Maria Herzner;Cristina Amparo Hagmann;Cristina Amparo Hagmann;Marion Goldeck;Steven Wolter

Frequent Co-Authors

Gunther Hartmann
Gunther Hartmann University Hospital Bonn
Marco Colonna
Marco Colonna Washington University in St. Louis
Veit Hornung
Veit Hornung Ludwig-Maximilians-Universität München
Dinshaw J. Patel
Dinshaw J. Patel Memorial Sloan Kettering Cancer Center
Marina Cella
Marina Cella Washington University in St. Louis
Roger A. Jones
Roger A. Jones Rutgers, The State University of New Jersey
Shizuo Akira
Shizuo Akira Osaka University
Thomas Tuschl
Thomas Tuschl Rockefeller University
Thomas Tüting
Thomas Tüting Otto-von-Guericke University Magdeburg
Ulrich Kalinke
Ulrich Kalinke Hannover Medical School

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Winfried Barchet

Trending Scientists

Recently Published Articles