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Brian D. Lichty

Brian D. Lichty

D-Index & Metrics

Microbiology

D-Index
57
Citations
12165
World Ranking
3568
National Ranking
102

Overview

Brian D. Lichty is affiliated with McMaster University in Canada. Their research primarily spans multiple disciplines within the life sciences, including Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology.

Their work extensively covers subfields such as Immunology, Molecular Biology, Genetics, Oncology, and Infectious Diseases. The main research topics they engage with include virus-based gene therapy research, CAR-T cell therapy research, immunotherapy and immune responses, SARS-CoV-2 and COVID-19 research, immune responses and vaccinations, immune cell function and interaction, and vaccine coverage and hesitancy.

Brian D. Lichty has published in several academic venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal for ImmunoTherapy of Cancer
  • Nature Communications
  • Scientific Reports
  • Nature reviews. Immunology

The scientist's recent notable papers include:

  • "Immunological considerations for COVID-19 vaccine strategies," 2020, published in Nature reviews. Immunology
  • "Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2," 2022, published in Cell
  • "Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination," 2021, published in Nature Communications
  • "RNA editing enzyme APOBEC3A promotes pro-inflammatory M1 macrophage polarization," 2021, published in Communications Biology
  • "CXCR6 by increasing retention of memory CD8+ T cells in the ovarian tumor microenvironment promotes immunosurveillance and control of ovarian cancer," 2021, published in Journal for ImmunoTherapy of Cancer

Their frequent collaborators include Maria Fe C. Medina, Sam Afkhami, Zhou Xing, AJ Robert McGray, and Mangalakumari Jeyanathan.

Best Publications

  • Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus.

    David F. Stojdl;Brian Lichty;Shane Knowles;Ricardo Marius

  • Immunological considerations for COVID-19 vaccine strategies.

    Mangalakumari Jeyanathan;Sam Afkhami;Fiona Smaill;Matthew S. Miller

  • VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents

    David F Stojdl;Brian D Lichty;Benjamin R tenOever;Jennifer M Paterson

  • Going viral with cancer immunotherapy

    Brian D. Lichty;Caroline J. Breitbach;David F. Stojdl;John C. Bell

  • Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2

    Unknown

  • Vesicular stomatitis virus: re-inventing the bullet

    Brian D Lichty;Anthony T Power;David F Stojdl;John C Bell

  • Neoadjuvant oncolytic virotherapy before surgery sensitizes triple-negative breast cancer to immune checkpoint therapy

    Marie-Claude Bourgeois-Daigneault;Marie-Claude Bourgeois-Daigneault;Dominic Guy Roy;Dominic Guy Roy;Amelia Sadie Aitken;Amelia Sadie Aitken;Nader El Sayes;Nader El Sayes

  • Intelligent Design: Combination Therapy With Oncolytic Viruses

    Kathryn Ottolino-Perry;Jean-Simon Diallo;Brian D Lichty;John C Bell

  • The Murine Double-Stranded RNA-Dependent Protein Kinase PKR Is Required for Resistance to Vesicular Stomatitis Virus

    David F. Stojdl;Ninan Abraham;Shane Knowles;Ricardo Marius

  • Carrier cell-based delivery of an oncolytic virus circumvents antiviral immunity.

    Anthony T Power;Jiahu Wang;Theresa J Falls;Jennifer M Paterson

  • Targeting Tumor Vasculature With an Oncolytic Virus

    Caroline J Breitbach;Naomi S De Silva;Theresa J Falls;Usaf Aladl

  • Potentiating Cancer Immunotherapy Using an Oncolytic Virus

    Byram W Bridle;Kyle B Stephenson;Jeanette E Boudreau;Sandeep Koshy

  • Maraba virus as a potent oncolytic vaccine vector.

    Jonathan G Pol;Liang Zhang;Byram W Bridle;Kyle B Stephenson

  • A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication.

    Robert E Edge;Theresa J Falls;Christopher W Brown;Brian D Lichty

  • Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity

    Carolina S Ilkow;Monique Marguerie;Cory Batenchuk;Justin Mayer

  • Synergistic interaction between oncolytic viruses augments tumor killing.

    Fabrice Le Boeuf;Fabrice Le Boeuf;Jean-Simon Diallo;Jean-Simon Diallo;J Andrea McCart;Steve Thorne

  • Getting oncolytic virus therapies off the ground

    John C Bell;Brian Lichty;David Stojdl

  • Cutting edge: FimH adhesin of type 1 fimbriae is a novel TLR4 ligand.

    Karen L. Mossman;M. Firoz Mian;Nicole M. Lauzon;Carlton L. Gyles

  • Induction of Innate Immunity against Herpes Simplex Virus Type 2 Infection via Local Delivery of Toll-Like Receptor Ligands Correlates with Beta Interferon Production

    Navkiran Gill;Philip M. Deacon;Brian Lichty;Karen L. Mossman

  • Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity.

    K B Stephenson;N G Barra;E Davies;A A Ashkar

  • Cigarette smoke impacts immune inflammatory responses to influenza in mice.

    Clinton S. Robbins;Carla M. T. Bauer;Neda Vujicic;Gordon J. Gaschler

  • Vesicular Stomatitis Virus as a Novel Cancer Vaccine Vector to Prime Antitumor Immunity Amenable to Rapid Boosting With Adenovirus

    Byram W Bridle;Jeanette E Boudreau;Brian D Lichty;Jérôme Brunellière

Frequent Co-Authors

John C. Bell
John C. Bell University of Ottawa
Yonghong Wan
Yonghong Wan McMaster University
Jonathan L. Bramson
Jonathan L. Bramson McMaster University
Ali A. Ashkar
Ali A. Ashkar McMaster University
Karen L. Mossman
Karen L. Mossman McMaster University
Zhou Xing
Zhou Xing McMaster University
Emily D. Cranston
Emily D. Cranston University of British Columbia
Nahum Sonenberg
Nahum Sonenberg McGill University
Suzanne Kamel-Reid
Suzanne Kamel-Reid University Health Network
Earl G. Brown
Earl G. Brown University of Ottawa

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