World's Best Scientists 2026 revealed!
Timothy Kottke

Timothy Kottke

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
10183
World Ranking
11054
National Ranking
4777

Timothy Kottke publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Timothy Kottke sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 145 publications — 24th percentile

24% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Timothy Kottke D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Timothy Kottke sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 62 D-Index — 46th percentile

46% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Timothy Kottke is affiliated with the Mayo Clinic in the United States and has contributed to research primarily in the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Their work encompasses several subfields including Genetics, Immunology, Oncology, Molecular Biology, and Infectious Diseases.

The scientist's research topics are centered around immunotherapy and immune responses, CAR-T cell therapy research, virus-based gene therapy, ocular oncology and treatments, vaccines and immunoinformatics approaches, glioma diagnosis and treatment, and viral infectious diseases with gene expression in insects.

Timothy Kottke has published in a variety of scientific journals. Frequent publication venues include:

  • Nature Communications
  • Frontiers in Immunology
  • Neuro-Oncology
  • Molecular Therapy - Oncolytics
  • International Journal of Environmental Research and Public Health

Their most recent papers include:

  • Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy, 2021, Nature Communications
  • APOBEC3B-mediated corruption of the tumor cell immunopeptidome induces heteroclitic neoepitopes for cancer immunotherapy, 2020, Nature Communications
  • A phase I oncolytic virus trial with vesicular stomatitis virus expressing human interferon beta and tyrosinase related protein 1 administered intratumorally and intravenously in uveal melanoma: safety, efficacy, and T cell responses, 2023, Frontiers in Immunology
  • Ad-CD40L mobilizes CD4 T cells for the treatment of brainstem tumors, 2020, Neuro-Oncology
  • Trap and ambush therapy using sequential primary and tumor escape-selective oncolytic viruses, 2023, Molecular Therapy - Oncolytics

Frequent collaborators in their research include Richard G. Vile, Jason M. Tonne, Jill Thompson, José S. Pulido, and Christopher B. Driscoll. These collaborators have coauthored multiple papers with Kottke, contributing to the development of research projects and publications.

Best Publications

  • Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory correlative trial.

    Judith E. Karp;Jeffrey E. Lancet;Scott H. Kaufmann;David W. End

  • Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade

    Adel Samson;Karen J. Scott;David Taggart;Emma J. West

  • Oncolytic immunovirotherapy for melanoma using vesicular stomatitis virus.

    Rosa Maria Diaz;Feorillo Galivo;Timothy Kottke;Phonphimon Wongthida

  • Caspase‐6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation

    Sandrine Ruchaud;Nadia Korfali;Pascal Villa;Timothy J. Kottke

  • Comparison of Apoptosis in Wild-Type and Fas-Resistant Cells: Chemotherapy-Induced Apoptosis Is Not Dependent on Fas/Fas Ligand Interactions

    Christine M. Eischen;Timothy J. Kottke;Timothy J. Kottke;Luis M. Martins;Luis M. Martins;Guriqbal S. Basi;Guriqbal S. Basi

  • G1 and G2 cell-cycle arrest following microtubule depolymerization in human breast cancer cells

    April L. Blajeski;Vy A. Phan;Timothy J. Kottke;Scott H. Kaufmann

  • Immune-Mediated Antitumor Activity of Reovirus Is Required for Therapy and Is Independent of Direct Viral Oncolysis and Replication

    Robin J. Prestwich;Elizabeth J. Ilett;Fiona Errington;Rosa M. Diaz

  • Activation of Multiple Interleukin-1β Converting Enzyme Homologues in Cytosol and Nuclei of HL-60 Cells during Etoposide-induced Apoptosis

    Luis M. Martins;Timothy Kottke;Peter W. Mesner;Guriqbal S. Basi

  • Tumor Infection by Oncolytic Reovirus Primes Adaptive Antitumor Immunity

    Robin J. Prestwich;Fiona Errington;Elizabeth J. Ilett;Ruth S.M. Morgan

  • Cell Carriers for Oncolytic Viruses: Fed Ex for Cancer Therapy

    Candice Willmon;Kevin Harrington;Timothy Kottke;Robin Prestwich

  • Cyclophosphamide Facilitates Antitumor Efficacy against Subcutaneous Tumors following Intravenous Delivery of Reovirus

    Jian Qiao;Hongxun Wang;Timothy Kottke;Christine White

  • Tumor-targeted, systemic delivery of therapeutic viral vectors using hitchhiking on antigen-specific T cells

    Caroline Cole;Jian Qiao;Timothy Kottke;Rosa Maria Diaz

  • Phase II Trial of Intravenous Administration of Reolysin(®) (Reovirus Serotype-3-dearing Strain) in Patients with Metastatic Melanoma.

    Evanthia Galanis;Svetomir N Markovic;Vera J Suman;Gerard J Nuovo

  • Purging metastases in lymphoid organs using a combination of antigen-nonspecific adoptive T cell therapy, oncolytic virotherapy and immunotherapy

    Jian Qiao;Timothy Kottke;Candice Willmon;Feorillo Galivo

  • Combination Therapy With Reovirus and Anti-PD-1 Blockade Controls Tumor Growth Through Innate and Adaptive Immune Responses

    Karishma Rajani;Christopher Parrish;Timothy Kottke;Jill Thompson

  • Comparison of caspase activation and subcellular localization in HL-60 and K562 cells undergoing etoposide-induced apoptosis.

    Luis M. Martins;Peter W. Mesner;Peter W. Mesner;Timothy J. Kottke;Timothy J. Kottke;Guriqbal S. Basi;Guriqbal S. Basi

  • Dendritic cells and T cells deliver oncolytic reovirus for tumour killing despite pre-existing anti-viral immunity.

    E J Ilett;R J Prestwich;T Kottke;F Errington

  • Flavopiridol Binds to Duplex DNA

    Keith C. Bible;Roy H. Bible;Timothy J. Kottke;Phyllis A. Svingen

  • Effects of the Bcr/abl kinase inhibitors STI571 and adaphostin (NSC 680410) on chronic myelogenous leukemia cells in vitro.

    Benjamin M. F. Mow;Benjamin M. F. Mow;Benjamin M. F. Mow;Joya Chandra;Joya Chandra;Joya Chandra;Phyllis A. Svingen;Phyllis A. Svingen;Phyllis A. Svingen;Christopher G. Hallgren;Christopher G. Hallgren;Christopher G. Hallgren

  • Transition from caspase-dependent to caspase-independent mechanisms at the onset of apoptotic execution.

    Kumiko Samejima;Shigenobu Toné;Timothy J. Kottke;Masato Enari

Frequent Co-Authors

Richard G. Vile
Richard G. Vile Mayo Clinic
Alan Melcher
Alan Melcher Institute of Cancer Research
Peter Selby
Peter Selby University of Leeds
Kevin J. Harrington
Kevin J. Harrington Royal Marsden NHS Foundation Trust
Matthew C. Coffey
Matthew C. Coffey Oncolytics Biotech (Canada)
William C. Earnshaw
William C. Earnshaw University of Edinburgh
Glen N. Barber
Glen N. Barber University of Miami
Atique U. Ahmed
Atique U. Ahmed Northwestern University
Reuben S. Harris
Reuben S. Harris The University of Texas Health Science Center at San Antonio

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