World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
96
Citations
29228
World Ranking
1850
National Ranking
1018

Overview

Stuart K. Calderwood is affiliated with Beth Israel Deaconess Medical Center in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant number of publications in related subfields such as molecular biology, cancer research, oncology, cell biology, and immunology.

The scientist's work extensively covers topics including heat shock proteins research, extracellular vesicles in disease, endoplasmic reticulum stress and disease, thermodynamics and calorimetric analyses, RNA research and splicing, microRNA in disease regulation, and cancer cells and metastasis.

Among recent notable publications are:

  • The functions and regulation of heat shock proteins; key orchestrators of proteostasis and the heat shock response, 2021, Archives of Toxicology
  • Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer, 2020, Journal of Extracellular Vesicles
  • Cell Stress Induced Stressome Release Including Damaged Membrane Vesicles and Extracellular HSP90 by Prostate Cancer Cells, 2020, Cells
  • HSF1: Primary Factor in Molecular Chaperone Expression and a Major Contributor to Cancer Morbidity, 2020, Cells
  • Extracellular Vesicles Enriched with Moonlighting Metalloproteinase Are Highly Transmissive, Pro-Tumorigenic, and Trans-Activates Cellular Communication Network Factor (CCN2/CTGF): CRISPR against Cancer, 2020, Cancers

Frequent co-authors collaborating with Stuart K. Calderwood include Benjamin Lang, Yuka Okusha, Takanori Eguchi, Ayesha Murshid, and Thiago J. Borges.

Common venues for publication comprise Preprints.org, Cell Stress and Chaperones, Methods in Molecular Biology, bioRxiv (Cold Spring Harbor Laboratory), and Cells.

Best Publications

  • HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine.

    Alexzander Asea;Stine-Kathrein Kraeft;Evelyn A. Kurt-Jones;Evelyn A. Kurt-Jones;Mary Ann Stevenson

  • Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.

    Alexzander Asea;Michael Rehli;Edith Kabingu;Jason A. Boch

  • Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications

    Daniel R. Ciocca;Stuart K. Calderwood;Stuart K. Calderwood

  • Heat shock proteins in cancer: chaperones of tumorigenesis.

    Stuart K. Calderwood;Stuart K. Calderwood;Abdul Khaleque;Douglas B. Sawyer;Daniel R. Ciocca

  • Sequential Phosphorylation by Mitogen-activated Protein Kinase and Glycogen Synthase Kinase 3 Represses Transcriptional Activation by Heat Shock Factor-1

    Boyang Chu;Fabrice Soncin;Brendan D. Price;Mary Ann Stevenson

  • Extracellular heat shock proteins in cell signaling.

    Stuart K. Calderwood;Salamatu S. Mambula;Philip J. Gray;Jimmy R. Theriault

  • Constitutive activation of IκB kinase α and NF-κB in prostate cancer cells is inhibited by ibuprofen

    S T Palayoor;M Y Youmell;S K Calderwood;C N Coleman

  • Heat Shock Protein 70 Is Secreted from Tumor Cells by a Nonclassical Pathway Involving Lysosomal Endosomes

    Salamatu S. Mambula;Stuart K. Calderwood

  • The Shock of Aging: Molecular Chaperones and the Heat Shock Response in Longevity and Aging – A Mini-Review

    Stuart K. Calderwood;Ayesha Murshid;Thomas Prince

  • Heat Shock Proteins Promote Cancer: It's a Protection Racket

    Stuart K. Calderwood;Jianlin Gong

  • Tumor-Derived Heat Shock Protein 70 Peptide Complexes Are Cross-Presented by Human Dendritic Cells

    Elfriede Noessner;Robert Gastpar;Valeria Milani;Anna Brandl

  • The dual immunoregulatory roles of stress proteins.

    Alan Graham Pockley;Munitta Muthana;Stuart K. Calderwood

  • X-Irradiation, Phorbol Esters, and H2O2 Stimulate Mitogen-activated Protein Kinase Activity in NIH-3T3 Cells through the Formation of Reactive Oxygen Intermediates

    Stevenson Ma;Pollock Ss;Coleman Cn;Calderwood Sk

  • TEMPERATURE RANGE AND SELECTIVE SENSITIVITY OF TUMORS TO HYPERTHERMIA: A CRITICAL REVIEW

    J. A. Dickson;S. K. Calderwood

  • Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update

    Daniel Ramon Ciocca;Andre Patrick Arrigo;Stuart K. Calderwood

  • Extracellular heat shock proteins in cell signaling and immunity

    Stuart K. Calderwood;Salamatu S. Mambula;Phillip J. Gray

  • Increases in Sequence Specific DNA Binding by p53 following Treatment with Chemotherapeutic and DNA Damaging Agents

    R B Tishler;S K Calderwood;C N Coleman;B D Price

  • Characterization and sequence of a mouse hsp70 gene and its expression in mouse cell lines.

    Clayton Hunt;Stuart Calderwood

  • Transcriptional Repression of the Prointerleukin 1β Gene by Heat Shock Factor 1

    Catherine M. Cahill;Wayne R. Waterman;Yue Xie;Philip E. Auron

  • Expression of heat shock proteins and heat shock protein messenger ribonucleic acid in human prostate carcinoma in vitro and in tumors in vivo

    Dan Tang;Abdul Khaleque;Ellen L. Jones;Jimmy R. Theriault

Frequent Co-Authors

Jianlin Gong
Jianlin Gong Boston University
Brendan D. Price
Brendan D. Price Harvard University
George M. Hahn
George M. Hahn Stanford University
Masaharu Takigawa
Masaharu Takigawa Okayama University
Philip E. Auron
Philip E. Auron Duquesne University
Michael Y. Sherman
Michael Y. Sherman Ariel University
Douglas B. Sawyer
Douglas B. Sawyer Maine Medical Center
Catherine M. Cahill
Catherine M. Cahill University of California, Los Angeles
Richard G. Vile
Richard G. Vile Mayo Clinic
Robert E. Kingston
Robert E. Kingston Harvard University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Stuart K. Calderwood

Trending Scientists