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Molecular Biology

D-Index
58
Citations
17434
World Ranking
2060
National Ranking
1026

Overview

Philip E. Auron is affiliated with Duquesne University in the United States. Their research spans several fields including Immunology and Microbiology, Biochemistry, Genetics and Molecular Biology, and Medicine. Key subfields of study in their work comprise Immunology, Molecular Biology, Hematology, and Oncology.

Their published work focuses on topics such as interferon and immune responses, Multiple Myeloma research and treatments, sphingolipid metabolism and signaling, ubiquitin and proteasome pathways, immune response and inflammation, immune cell function and interaction, and melanoma and MAPK pathways.

Frequent coauthors in their publications include David A. Macar, Deborah L. Galson, Daniela N. Petrusca, Patrick L. Mulcrone, and Ryan T. Bishop. Their collaborative research has appeared in journals such as Cancers, The Journal of Immunology, and Journal of Clinical Investigation.

Notable papers authored or co-authored by Philip E. Auron include:

  • GFI1-Dependent Repression of SGPP1 Increases Multiple Myeloma Cell Survival, 2022, Cancers
  • Distinct hypoxic molecular mechanisms differentially regulate human vs. mouse Interleukin 1β gene expression in monocytes/macrophages, 2023, The Journal of Immunology
  • EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis, 2025, Journal of Clinical Investigation

Best Publications

  • Succinate is an inflammatory signal that induces IL-1β through HIF-1α

    G. M. Tannahill;A. M. Curtis;J. Adamik;E. M. Palsson-McDermott

  • Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.

    Alexzander Asea;Michael Rehli;Edith Kabingu;Jason A. Boch

  • Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.

    Philip E. Auron;Andrew C. Webb;Lanny J. Rosenwasser;Steven F. Mucci

  • Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFκB

    Jinbo Yang;Xudong Liao;Mukesh K. Agarwal;Laura Barnes

  • Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1.

    Pu Zhang;Gerhard Behre;Jing Pan;Atsushi Iwama

  • Multiple biological activities of human recombinant interleukin 1.

    C A Dinarello;J G Cannon;J W Mier;H A Bernheim

  • The CCAAT/enhancer (C/EBP) family of basic-leucine zipper (bZIP) transcription factors is a multifaceted highly-regulated system for gene regulation

    Junichi Tsukada;Yasuhiro Yoshida;Yoshihiko Kominato;Philip E. Auron

  • Translational control during the acute phase response. Ferritin synthesis in response to interleukin-1.

    J T Rogers;K R Bridges;G P Durmowicz;J Glass

  • Genomic sequence for human prointerleukin 1 beta: possible evolution from a reverse transcribed prointerleukin 1 alpha gene

    Burton D. Clark;Kathieen L. Collins;Melinda S. Gandy;Andrew C. Webb

  • THE INTERLEUKIN 1 RECEPTOR : LIGAND INTERACTIONS AND SIGNAL TRANSDUCTION

    Philip E. Auron

  • Human pro-IL-1 beta gene expression in monocytic cells is regulated by two distinct pathways.

    M J Fenton;M W Vermeulen;B D Clark;A C Webb

  • Transcriptional Repression of the Prointerleukin 1β Gene by Heat Shock Factor 1

    Catherine M. Cahill;Wayne R. Waterman;Yue Xie;Philip E. Auron

  • Studies on the molecular nature of human interleukin 1.

    P E Auron;S J Warner;A C Webb;J G Cannon

  • Cloning, characterization, and expression of a human calcitonin receptor from an ovarian carcinoma cell line.

    Alan H. Gorn;Herbert Y. Lin;Moshe Yamin;Philip E. Auron

  • The human prointerleukin 1 beta gene requires DNA sequences both proximal and distal to the transcription start site for tissue-specific induction.

    F Shirakawa;K Saito;C A Bonagura;D L Galson

  • Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/PU.1, and is restricted in expression to hematopoietic cells and the testis.

    D L Galson;J O Hensold;T R Bishop;M Schalling

  • Transcriptional regulation of the human prointerleukin 1 beta gene.

    M J Fenton;B D Clark;K L Collins;A C Webb

  • Transcription factors NF-IL6 and CREB recognize a common essential site in the human prointerleukin 1 beta gene.

    J Tsukada;K Saito;W R Waterman;A C Webb

  • Heat Shock Factor 1 Represses Transcription of the IL-1β Gene through Physical Interaction with the Nuclear Factor of Interleukin 6 *

    Yue Xie;Changmin Chen;Mary Ann Stevenson;Philip E. Auron

  • Monocyte expression of the human prointerleukin 1 beta gene (IL1B) is dependent on promoter sequences which bind the hematopoietic transcription factor Spi-1/PU.1.

    Y. Kominato;D. L. Galson;W. R. Waterman;A. C. Webb

Frequent Co-Authors

Lanny J. Rosenwasser
Lanny J. Rosenwasser University of Colorado Anschutz Medical Campus
Charles A. Dinarello
Charles A. Dinarello University of Colorado Anschutz Medical Campus
Lee Gehrke
Lee Gehrke Harvard University
Sheldon M. Wolff
Sheldon M. Wolff Tufts Medical Center
Stuart K. Calderwood
Stuart K. Calderwood Beth Israel Deaconess Medical Center
Luke A. J. O'Neill
Luke A. J. O'Neill Trinity College Dublin
Thomas B. Shows
Thomas B. Shows Roswell Park Cancer Institute
Mary B. Goldring
Mary B. Goldring Hospital for Special Surgery
Mark F. Stinski
Mark F. Stinski University of Iowa

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