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Biology and Biochemistry

D-Index
50
Citations
11048
World Ranking
17520
National Ranking
1211

Overview

Beate E. Kehrel is affiliated with the University of Münster in Germany and has contributed significantly to the field of medicine, with a concentration on hematology, surgery, cardiology and cardiovascular medicine, pulmonary and respiratory medicine, and genetics. Their research focuses on platelet disorders and treatments, mechanisms of blood coagulation and thrombosis, antiplatelet therapy and cardiovascular diseases, blood properties and coagulation, pharmacological effects and toxicity studies, hemophilia treatment and research, and cell adhesion molecules research.

Recent publications demonstrate a range of topics centered around platelet physiology, thrombosis, and interactions at the molecular level. Selected recent papers include:

  • Platelets: Physiology and Biochemistry, 2023, Seminars in Thrombosis and Hemostasis
  • CD36-fibrin interaction propagates FXI-dependent thrombin generation of human platelets, 2020, The FASEB Journal
  • Age-Dependent Control of Collagen-Dependent Platelet Responses by Thrombospondin-1-Comparative Analysis of Platelets from Neonates, Children, Adolescents, and Adults, 2021, International Journal of Molecular Sciences
  • Thrombogenicity of the p48 and anti-thrombogenic p48 hydrophilic polymer coating low-profile flow diverters in an in vitro human thrombin generation model, 2020, Interventional Neuroradiology
  • Antagonistic Roles of Human Platelet Integrin αIIbβ3 and Chemokines in Regulating Neutrophil Activation and Fate on Arterial Thrombi Under Flow, 2023, Arteriosclerosis Thrombosis and Vascular Biology

Their frequent coauthors include Kerstin Jurk, Barbara Zieger, Martin F. Brodde, Anke C. Fender, and Karina Althaus, suggesting collaborative research mainly in hematology and related fields.

Beate E. Kehrel publishes regularly in several academic journals. The most frequent venues are:

  • International Journal of Molecular Sciences (4 publications)
  • Hämostaseologie (3 publications)
  • Seminars in Thrombosis and Hemostasis
  • The FASEB Journal
  • Arteriosclerosis Thrombosis and Vascular Biology

The breadth of their work primarily spans medicine, with an emphasis on hematology. Within this domain, their exploration includes platelet biology, coagulation pathways, and cardiovascular implications, reflecting a multidisciplinary approach to understanding blood-related disorders and treatments.

Best Publications

  • HDL and arteriosclerosis: beyond reverse cholesterol transport.

    Jerzy-Roch Nofer;Beate Kehrel;Manfred Fobker;Bodo Levkau

  • Platelets: physiology and biochemistry.

    Kerstin Jurk;Beate E. Kehrel

  • P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is Expressed on Platelets and Can Mediate Platelet–Endothelial Interactions in Vivo

    Paul S. Frenette;Cécile V. Denis;Linnea Weiss;Kerstin Jurk

  • Platelet Activation and Signal Transduction by Convulxin, a C-type Lectin from Crotalus durissus terrificus (Tropical Rattlesnake) Venom via the p62/GPVI Collagen Receptor

    János Polgár;Jeannine M. Clemetson;Beate E. Kehrel;Markus Wiedemann

  • Glycoprotein VI Is a Major Collagen Receptor for Platelet Activation: It Recognizes the Platelet-Activating Quaternary Structure of Collagen, Whereas CD36, Glycoprotein IIb/IIIa, and von Willebrand Factor Do Not

    B Kehrel;S Wierwille;K J Clemetson;O Anders

  • Thrombosis and platelets: an update

    Milka Koupenova;Beate E. Kehrel;Heather A. Corkrey;Jane E. Freedman

  • Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells.

    Dorothee Viemann;Anke Strey;Annette Janning;Kerstin Jurk

  • Large platelets circulate in an activated state in diabetes mellitus

    D. Tschoepe;P. Roesen;J. Esser;B. Schwippert

  • The vasodilator-stimulated phosphoprotein (VASP) is involved in cGMP- and cAMP-mediated inhibition of agonist-induced platelet aggregation, but is dispensable for smooth muscle function.

    Attila Aszódi;Alexander Pfeifer;Alexander Pfeifer;Marianne Ahmad;Martin Glauner

  • Protein A is the von Willebrand factor binding protein onStaphylococcus aureus

    Jörg Hartleib;Nicola Köhler;Richard B. Dickinson;Gursharan S. Chhatwal

  • Evidence for abnormal platelet glycoprotein expression in diabetes mellitus.

    D. Tschoepe;P. Roesen;L. Kaufmann;S. Schauseil

  • NBEAL2 is mutated in Gray Platelet Syndrome and is required for biogenesis of platelet alpha-granules

    Meral Gunay-Aygun;Tzipora C Falik-Zaccai;Thierry Vilboux;Yifat Zivony-Elboum

  • Platelet membrane activation markers are predictive for increased risk of acute ischemic events after PTCA.

    D Tschoepe;H P Schultheiss;P Kolarov;B Schwippert

  • Sustained integrin ligation involves extracellular free sulfhydryls and enzymatically catalyzed disulfide exchange

    Judith Lahav;Kerstin Jurk;Oded Hess;Michael J. Barnes

  • Deficiency of intact thrombospondin and membrane glycoprotein Ia in platelets with defective collagen-induced aggregation and spontaneous loss of disorder

    B Kehrel;L Balleisen;R Kokott;R Mesters

  • The GPIb thrombin-binding site is essential for thrombin-induced platelet procoagulant activity.

    Dagmar Dörmann;Kenneth J. Clemetson;Kenneth J. Clemetson;Beate E. Kehrel;Beate E. Kehrel

  • Thrombospondin-1 mediates platelet adhesion at high shear via glycoprotein Ib (GPIb): an alternative/backup mechanism to von Willebrand factor.

    Kerstin Jurk;Kenneth J. Clemetson;Philip G. de Groot;Martin F. Brodde

  • HDL3-Mediated Inhibition of Thrombin-Induced Platelet Aggregation and Fibrinogen Binding Occurs via Decreased Production of Phosphoinositide-Derived Second Messengers 1,2-Diacylglycerol and Inositol 1,4,5-tris-Phosphate

    Jerzy-Roch Nofer;Michael Walter;Beate Kehrel;Sonja Wierwille

  • Molecular characterization of a novel Staphylococcus aureus surface protein (SasC) involved in cell aggregation and biofilm accumulation.

    Katrin Schroeder;Mario Jularic;Samantha M. Horsburgh;Nina Hirschhausen

  • The platelet glycoprotein IIb/IIIa complex is involved in the adhesion of activated platelets to leukocytes.

    Peter Spangenberg;Helge Redlich;Iris Bergmann;Wolfgang Lösche

Frequent Co-Authors

Kenneth J. Clemetson
Kenneth J. Clemetson University of Bern
Georg Peters
Georg Peters University of Münster
Hugo Van Aken
Hugo Van Aken University of Münster
Gerd Assmann
Gerd Assmann University of Münster
Udo Seedorf
Udo Seedorf Universität Hamburg
Mathias Herrmann
Mathias Herrmann Saarland University
Sven G. Meuth
Sven G. Meuth University of Münster
Richard W. Farndale
Richard W. Farndale University of Cambridge
Heinz Wiendl
Heinz Wiendl University of Münster
Christoph Kleinschnitz
Christoph Kleinschnitz University of Duisburg-Essen

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