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Biology and Biochemistry

D-Index
59
Citations
10510
World Ranking
12737
National Ranking
992

Overview

Jonathan M. Gibbins is affiliated with the University of Reading in the United Kingdom. Their research focuses primarily on medicine, with significant work in biochemistry, genetics, and molecular biology. Subfields of particular interest include hematology, molecular biology, cardiology and cardiovascular medicine, pulmonary and respiratory medicine, and immunology.

The scientist's main topics of study involve platelet disorders and treatments, blood properties and coagulation, antiplatelet therapy and cardiovascular diseases, COVID-19 clinical research studies, the complement system in diseases, adipokines related to inflammation and metabolic diseases, and receptor mechanisms and signaling.

Jonathan M. Gibbins has published extensively in several scientific venues. The frequent publication venues include Blood, Scientific Reports, Platelets, bioRxiv (Cold Spring Harbor Laboratory), and Free Radical Biology and Medicine.

  • Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets, 2021, Blood
  • Immobility-associated thromboprotection is conserved across mammalian species from bear to human, 2023, Science
  • Myricetin, the Main Flavonoid in Syzygium cumini Leaf, Is a Novel Inhibitor of Platelet Thiol Isomerases PDI and ERp5, 2020, Frontiers in Pharmacology
  • Mode of induction of platelet-derived extracellular vesicles is a critical determinant of their phenotype and function, 2020, Scientific Reports
  • Platelet-derived extracellular vesicles express NADPH oxidase-1 (Nox-1), generate superoxide and modulate platelet function, 2021, Free Radical Biology and Medicine

Collaborations feature a number of frequent co-authors, including Alexander P. Bye, Neline Kriek, Tanya Sage, Joanne L. Dunster, and Joanne Mitchell.

Best Publications

  • The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen

    A. Poole;J.M. Gibbins;M. Turner;M.J. van Vugt

  • Platelet adhesion signalling and the regulation of thrombus formation

    Jonathan M. Gibbins

  • Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor γ-chain

    Jonathan M Gibbins;Minoru Okuma;Richard Farndale;Michael Barnes

  • Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in humans.

    G. P. Hubbard;S. Wolffram;J. A. Lovegrove;J. M. Gibbins

  • Tyrosine phosphorylation of the Fc receptor gamma-chain in collagen-stimulated platelets.

    Jonathan Gibbins;Judith Asselin;Richard Farndale;Michael Barnes

  • A Collagen-Like Peptide Stimulates Tyrosine Phosphorylation of syk and Phospholipase Cγ2 in Platelets Independent of the Integrin α2β1

    Judith Asselin;Jonathan M. Gibbins;Marcus Achison;Young Han Lee

  • Platelet PECAM-1 inhibits thrombus formation in vivo

    Shahrokh Falati;Sonali Patil;Peter L. Gross;Michelle Stapleton

  • Collagen receptor signalling in platelets: extending the role of the ITAM

    Steve P Watson;Jonathan Gibbins

  • Platelet endothelial cell adhesion molecule-1 signaling inhibits the activation of human platelets

    Milenko Cicmil;Joanne M. Thomas;Joanne M. Thomas;Mireille Leduc;Mireille Leduc;Cassian Bon;Cassian Bon

  • Extracellular disulfide exchange and the regulation of cellular function

    Peter A. Jordan;Jonathan M. Gibbins

  • Future innovations in anti-platelet therapies

    N E Barrett;L Holbrook;S Jones;W J Kaiser

  • Platelet protein disulfide isomerase is required for thrombus formation but not for hemostasis in mice

    Kyungho Kim;Eunsil Hahm;Jing Li;Lisa-Marie Holbrook

  • Ingestion of onion soup high in quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in man : a pilot study

    Gary P. Hubbard;Siegfried Wolffram;Ric de Vos;Arnaud Bovy

  • A role for the thiol isomerase protein ERP5 in platelet function

    Peter A. Jordan;Joanne M. Stevens;Gary P. Hubbard;Gary P. Hubbard;Natasha E. Barrett;Natasha E. Barrett

  • The p85 Subunit of Phosphatidylinositol 3-Kinase Associates with the Fc Receptor γ-Chain and Linker for Activitor of T Cells (LAT) in Platelets Stimulated by Collagen and Convulxin

    Jonathan M. Gibbins;Stephen Briddon;Adam Shutes;Martine J. van Vugt

  • Quercetin inhibits collagen-stimulated platelet activation through inhibition of multiple components of the glycoprotein VI signaling pathway

    G P Hubbard;J M Stevens;M Cicmil;T Sage

  • Snakebite and Its Socio-Economic Impact on the Rural Population of Tamil Nadu, India

    Sakthivel Vaiyapuri;Rajendran Vaiyapuri;Rajesh Ashokan;Karthikeyan Ramasamy

  • A structural basis for the inhibition of collagen-stimulated platelet function by quercetin and structurally related flavonoids.

    Bernice Wright;Leonardo A Moraes;Charles F Kemp;William Mullen

  • Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib

    Alexander P. Bye;Amanda J. Unsworth;Michael J. Desborough;Michael J. Desborough;Catherine A. T. Hildyard

  • Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation.

    Lisa-Marie Holbrook;Nicholas A. Watkins;Alan D. Simmonds;Chris I. Jones

Frequent Co-Authors

Katherine L. Tucker
Katherine L. Tucker University of Massachusetts Lowell
Steve P. Watson
Steve P. Watson University of Birmingham
Willem H. Ouwehand
Willem H. Ouwehand University of Cambridge
Richard W. Farndale
Richard W. Farndale University of Cambridge
Cassian Bon
Cassian Bon Institut Pasteur
Mike Barnes
Mike Barnes University of Manchester
Jeremy P. E. Spencer
Jeremy P. E. Spencer University of Reading
Alison H. Goodall
Alison H. Goodall University of Leicester
Ian M. Jones
Ian M. Jones University of Reading
Roger D. Cox
Roger D. Cox Medical Research Council

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