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Biology and Biochemistry

D-Index
98
Citations
38278
World Ranking
1653
National Ranking
924

Overview

Bruce Furie is affiliated with Beth Israel Deaconess Medical Center in the United States and focuses primarily on medical research with an emphasis on hematology.

Their work spans several subfields within medicine, including hematology, epidemiology, and surgery. The main topics addressed in their research consist of blood coagulation and thrombosis mechanisms, hemophilia treatment and research, platelet disorders and treatments, adipokines, inflammation and metabolic diseases, as well as lipoproteins and cardiovascular health.

Their recent publications include:

  • A coagulation defect arising from heterozygous premature termination of tissue factor, 2020, Journal of Clinical Investigation
  • Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin, 2020, UNC Libraries

Frequent coauthors collaborating with Bruce Furie include:

  • Sol Schulman
  • Emale El-Darzi
  • Mary H.C. Florido
  • Max Friesen
  • Glenn Merrill-Skoloff

Their research has appeared in venues such as:

  • Journal of Clinical Investigation
  • UNC Libraries

Bruce Furie's contributions to the field of medicine are marked by a focus on complex mechanisms underlying blood coagulation and related disorders. Their investigations into tissue factor, platelet function, and inflammation intersect with cardiovascular health and metabolic disease pathways, forming a multidisciplinary approach within clinical and translational research.

Best Publications

  • Mechanisms of Thrombus Formation

    Bruce Furie;Barbara C. Furie

  • The molecular basis of blood coagulation

    Bruce Furie;Barbara C. Furie

  • PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytes.

    Eric Larsen;Alessandro Celi;Gary E. Gilbert;Barbara C. Furie

  • Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets.

    Theresa Palabrica;Roy Lobb;Barbara C. Furie;Mark Aronovitz

  • Accumulation of Tissue Factor into Developing Thrombi In Vivo Is Dependent upon Microparticle P-Selectin Glycoprotein Ligand 1 and Platelet P-Selectin

    Shahrokh Falati;Qingde Liu;Peter Gross;Glenn Merrill-Skoloff

  • Des-gamma-carboxy (abnormal) prothrombin as a serum marker of primary hepatocellular carcinoma.

    Howard A. Liebman;Barbara C. Furie;Myron J. Tong;Rita A. Blanchard

  • Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse.

    Shahrokh Falati;Peter Gross;Glenn Merrill-Skoloff;Barbara C. Furie

  • Molecular and cellular biology of blood coagulation.

    Bruce Furie;Barbara C. Furie

  • Polyspecific monoclonal lupus autoantibodies reactive with both polynucleotides and phospholipids

    Eileen M Lafer;J. Rauch;C. Andrzejewski;D. Mudd

  • Thrombus formation in vivo.

    Bruce Furie;Barbara C. Furie

  • Tumor-derived tissue factor-bearing microparticles are associated with venous thromboembolic events in malignancy.

    Jeffrey I. Zwicker;Howard A. Liebman;Donna Neuberg;Romaric Lacroix

  • A platelet membrane protein expressed during platelet activation and secretion. Studies using a monoclonal antibody specific for thrombin-activated platelets.

    S Hsu-Lin;C L Berman;B C Furie;D August

  • Vitamin K-Dependent Biosynthesis of γ-Carboxyglutamic Acid

    Bruce Furie;Beth A. Bouchard;Barbara C. Furie

  • PADGEM-dependent adhesion of platelets to monocytes and neutrophils is mediated by a lineage-specific carbohydrate, LNF III (CD15)

    Eric Larsen;Theresa Palabrica;Susan Sajer;Gary E. Gllbert

  • A platelet alpha granule membrane protein that is associated with the plasma membrane after activation. Characterization and subcellular localization of platelet activation-dependent granule-external membrane protein.

    C. L. Berman;E. L. Yeo;June D. Wencel-Drake;B. C. Furie

  • Selectins: A family of adhesion receptors

    M. Bevilacqua;E. Butcher;Barbara Furie;Bruce Furie

  • Localization of labile posttranslational modifications by electron capture dissociation: The case of γ-carboxyglutamic acid

    Neil L. Kelleher;Roman A. Zubarev;Kristine Bush;Bruce Furie

  • Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation.

    Janet Chou;Nigel Mackman;Glenn Merrill-Skoloff;Brian Pedersen

  • A critical role for extracellular protein disulfide isomerase during thrombus formation in mice

    Jaehyung Cho;Barbara C. Furie;Shaun R. Coughlin;Bruce Furie

  • Role of platelet P-selectin and microparticle PSGL-1 in thrombus formation.

    Bruce Furie;Barbara C. Furie

Frequent Co-Authors

Barbara C. Furie
Barbara C. Furie Tufts University
Robert Flaumenhaft
Robert Flaumenhaft Beth Israel Deaconess Medical Center
Mingdong Huang
Mingdong Huang Fuzhou University
Johan Stenflo
Johan Stenflo Lund University
Christopher T. Walsh
Christopher T. Walsh Stanford University
Nigel Mackman
Nigel Mackman University of North Carolina at Chapel Hill
Kenneth A. Bauer
Kenneth A. Bauer Beth Israel Deaconess Medical Center
Donna Neuberg
Donna Neuberg Harvard University
Athan Kuliopulos
Athan Kuliopulos Tufts University
Willem H. Ouwehand
Willem H. Ouwehand University of Cambridge

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