Rudolf Grosschedl

Research.com Recognitions

• 2024 - Research.com Genetics and Molecular Biology in Germany Leader Award
• 2013 - Member of Academia Europaea

Overview

Best Publications

• Functional interaction of beta-catenin with the transcription factor LEF-1.

  Behrens J;von Kries Jp;Kühl M;Bruhn L;Bruhn L

  3859
  Citations

• Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice.

  C van Genderen;R M Okamura;I Fariñas;R G Quo

  1188
  Citations

• HMG domain proteins: architectural elements in the assembly of nucleoprotein structures

  Rudolf Grosschedl;Klaus Giese;John Pagel

  1066
  Citations

• Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice.

  Ann S. Tsukamoto;Rudolf Grosschedl;Raphael C. Guzman;Tristram Parslow

  930
  Citations

• The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

  Klaus Giese;Jeffery Cox;Rudolf Grosschedl

  879
  Citations

• Failure of B-cell differentiation in mice lacking the transcription factor EBF

  Haishan Lin;Rudolf Grosschedl

  831
  Citations

• LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

  A Travis;A Amsterdam;C Belanger;R Grosschedl

  791
  Citations

• Satb2 regulates callosal projection neuron identity in the developing cerebral cortex.

  Elizabeth A. Alcamo;Laura Chirivella;Marcel Dautzenberg;Gergana Dobreva

  745
  Citations

• Structural basis for DNA bending by the architectural transcription factor LEF-1

  John J. Love;Xiang Li;David A. Case;Klaus Giese

  745
  Citations

• Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma

  Jessica Okosun;Csaba Bödör;Jun Wang;Shamzah Araf

  738
  Citations

• Regulation of LEF-1/TCF transcription factors by Wnt and other signals

  Quinn Eastman;Rudolf Grosschedl

  730
  Citations

• Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions.

  K Giese;C Kingsley;J R Kirshner;R Grosschedl

  713
  Citations

• PIASy, a nuclear matrix–associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

  Shrikesh Sachdev;Laurakay Bruhn;Heidemarie Sieber;Andrea Pichler

  664
  Citations

• Cell-type specificity of iminunoglobulin gene expression is regulated by at least three DNA sequence elements

  Rudolf Grosschedl;David Baltimore Whitehead

  643
  Citations

• Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo

  R Grosschedl;M L Birnstiel

  608
  Citations

• Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways.

  Anton Novak;Shu-Chi Hsu;Chungyee Leung-Hagesteijn;Galina Radeva

  594
  Citations

• SATB2 Is a Multifunctional Determinant of Craniofacial Patterning and Osteoblast Differentiation

  Gergana Dobreva;Maria Chahrour;Marcel Dautzenberg;Laura Chirivella

  592
  Citations

• Wnt Signaling Regulates B Lymphocyte Proliferation through a LEF-1 Dependent Mechanism

  Tannishtha Reya;Mary O'Riordan;Ross Okamura;Erik Devaney

  574
  Citations

• Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice.

  Juan Galceran;Isabel Fariñas;Michael J. Depew;Hans Clevers

  570
  Citations

• Lef1 expression is activated by BMP-4 and regulates inductive tissue interactions in tooth and hair development.

  K Kratochwil;M Dull;I Farinas;J Galceran

  535
  Citations