World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
92
Citations
46900
World Ranking
988
National Ranking
539

Molecular Biology

D-Index
93
Citations
47589
World Ranking
663
National Ranking
365

Overview

Cornelis Murre is a researcher affiliated with the University of California, San Diego in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology as well as Immunology and Microbiology.

Their work covers multiple subfields including Molecular Biology, Immunology, Plant Science, Genetics, and Cancer Research. The main research topics addressed in their publications focus on T-cell and B-cell Immunology, Genomics and Chromatin Dynamics, Immune Cell Function and Interaction, RNA Research and Splicing, RNA and protein synthesis mechanisms, Single-cell and spatial transcriptomics, and Immunotherapy and Immune Responses.

The scientist has contributed to several notable papers, such as:

  • Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses, 2020, Science Immunology
  • Early precursors and molecular determinants of tissue-resident memory CD8 + T lymphocytes revealed by single-cell RNA sequencing, 2020, Science Immunology
  • Calcium signaling instructs NIPBL recruitment at active enhancers and promoters via distinct mechanisms to reconstruct genome compartmentalization, 2020, Genes & Development
  • FOXO1 constrains activation and regulates senescence in CD8 T cells, 2021, Cell Reports
  • Upon microbial challenge, human neutrophils undergo rapid changes in nuclear architecture and chromatin folding to orchestrate an immediate inflammatory gene program, 2020, Genes & Development

Frequent coauthors with whom they have collaborated include:

  • Zhaoren He
  • John W. Sedat
  • Angus McDonald
  • Ananda W. Goldrath
  • Hanbin Lu

Publication venues where Cornelis Murre has often appeared are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Proceedings of the National Academy of Sciences
  • Science Immunology
  • Genes & Development

Best Publications

  • Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

    Sven Heinz;Christopher Benner;Nathanael Spann;Eric Bertolino

  • A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

    Cornelis Murre;Patrick Schonleber McCaw;David Baltimore

  • Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms.

    Mark Eben Massari;Cornelis Murre

  • Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence.

    Cornelis Murre;Patrick Schonleber McCaw;H. Vaessin;M. Caudy

  • Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo

    Andrew B. Lassar;Robert L. Davis;Woodring E. Wright;Tom Kadesch

  • E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

    Gretchen Bain;Els C.Robanus Maandag;David J. Izon;Derk Amsen

  • A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL.

    Mark P. Kamps;Cornelis Murre;Xiao hong Sun;David Baltimore

  • Structure and function of helix-loop-helix proteins.

    Cornelis Murre;Gretchen Bain;Marc A. van Dijk;Isaac Engel

  • A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

    Yin C Lin;Suchit Jhunjhunwala;Christopher Benner;Sven Heinz

  • E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas.

    G. Bain;I. Engel;E. C. Robanus Maandag;H. P. J. Te Riele

  • The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets.

    Cliff Y Yang;J Adam Best;Jamie Knell;Edward Yang

  • Helix-loop-helix proteins and lymphocyte development

    Cornelis Murre

  • Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12.

    Barbara L. Kee;Cornelis Murre

  • extradenticle Raises the DNA binding specificity of homeotic selector gene products

    Marc A. van Dijk;Cornelis Murre

  • E-proteins directly regulate expression of activation-induced deaminase in mature B cells

    Camil Elie Sayegh;Melanie W Quong;Yasutoshi Agata;Cornelis Murre

  • Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade

    Gretchen Bain;Celia B. Cravatt;Cindy Loomans;Jose Alberola-Ila

  • The 3D Structure of the Immunoglobulin Heavy-Chain Locus: Implications for Long-Range Genomic Interactions

    Suchit Jhunjhunwala;Menno C. van Zelm;Mandy M. Peak;Steve Cutchin

  • E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells.

    William J Romanow;Anton W Langerak;Peter Goebel;Ingrid L.M Wolvers-Tettero

  • Non-coding transcription instructs chromatin folding and compartmentalization to dictate enhancer-promoter communication and t cell fate

    Takeshi Isoda;Amanda J. Moore;Zhaoren He;Vivek Chandra

  • CTCF-binding elements mediate control of V(D)J recombination

    Chunguang Guo;Hye Suk Yoon;Hye Suk Yoon;Andrew Franklin;Andrew Franklin;Suvi Jain;Suvi Jain

  • Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate

    Yin C Lin;Christopher Benner;Christopher Benner;Robert Mansson;Sven Heinz

Frequent Co-Authors

Jonathan G. Seidman
Jonathan G. Seidman Harvard University
Christopher Benner
Christopher Benner University of California, San Diego
Ann J. Feeney
Ann J. Feeney Scripps Research Institute
David Baltimore
David Baltimore California Institute of Technology
Christopher K. Glass
Christopher K. Glass University of California, San Diego
Hiroshi Kawamoto
Hiroshi Kawamoto Kyoto University
John T. Chang
John T. Chang University of California, San Diego
Thomas Quertermous
Thomas Quertermous Stanford University
Menno C. van Zelm
Menno C. van Zelm Monash University
Ananda W. Goldrath
Ananda W. Goldrath University of California, San Diego

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